scholarly journals OPTIMIZATION OF VV DELAY OF CRT IS MORE REPRODUCIBLE USING PEAK VELOCITIES THAN USING VELOCITY TIME INTEGRAL, AS WELL AS BEING QUICKER

2011 ◽  
Vol 57 (14) ◽  
pp. E802
Author(s):  
Punam A. Pabari ◽  
Andreas Kyriacou ◽  
Michela Moraldo ◽  
Alun D. Hughes ◽  
Jamil Mayet ◽  
...  
2020 ◽  
Vol 48 (5) ◽  
pp. 504-508
Author(s):  
Ya Tan ◽  
Shi Zeng ◽  
YuShan Liu ◽  
HuaYu Tang ◽  
BaiHua Zhao

AbstractObjectiveTo observe Doppler ultrasound changes in the two segments of the posterior cerebral artery (PCA) in fetuses with transposition of the great arteries (TGA).MethodsThe peak systolic velocity (PSV), end-diastolic velocity (EDV), pulsatility index (PI), and velocity-time integral (VTI) of the two segments of PCA (the first segment: PCAS1, the second segment: PCAS2) and of the middle cerebral artery (MCA) were compared in TGA fetuses and normal fetuses. The abnormality rate between the PCAS1-PI and MCA-PI was compared in TGA fetuses.ResultsThe PCAS1-PI and MCA-PI were smaller in the TGA fetuses than in the controls (all P < 0.05), but the PCAS2-PI was unchanged (P > 0.05). The MCA-VTI, PCAS1-VTI, and PCAS2-VTI were larger in the TGA fetuses (all P < 0.05). In the TGA fetuses, the abnormality rate of the PCAS1-PI was significantly higher than that of the MCA-PI (P < 0.05).ConclusionIn fetuses with TGA, there were hemodynamic differences between the two segments of the posterior cerebral arteries. Moreover, PCAS1 exhibited signs of vasodilatation more obviously than did the MCA in fetuses with TGA.


2019 ◽  
Vol 55 (5) ◽  
pp. 823-828
Author(s):  
Shuichi Shiraishi ◽  
Keiko Bamba ◽  
Ai Sugimoto ◽  
Masashi Takahashi ◽  
Masanori Tsuchida

Heart ◽  
2017 ◽  
Vol 103 (Suppl 5) ◽  
pp. A93-A93
Author(s):  
Graham Cole ◽  
Stefania Sacchi ◽  
Niti Dhutia ◽  
Matthew Shun-Shin ◽  
Massoud Zolgharni ◽  
...  

2021 ◽  
Vol 2 (Supplement_1) ◽  
pp. A3-A4
Author(s):  
P Vokolos ◽  
D Kennedy ◽  
K Lushington ◽  
J Martin ◽  
D Wabnitz ◽  
...  

Abstract Children with sleep disordered breathing (SDB) have evidence of increased blood flow velocity and sympathetic overactivity. Sympathetic overactivity leads to peripheral vasoconstriction, increased vascular resistance and consequently, increases blood flow velocity. Early vascular ageing involves premature arterial thickening and stiffening that leads to changes in vascular function. Both increased blood flow velocity and sympathetic overactivity are promoters of arterial remodelling and hence, early vascular ageing. No studies have directly histologically investigated arterial wall structure in children with SDB and how it relates to vascular function. Thirty-six children scheduled for tonsillectomy underwent polysomnography to determine SDB severity and resting brachial artery blood flow velocity (velocity time integral and peak systolic velocity) using Doppler ultrasound. The dorsal lingual artery (tonsil) was stained using hematoxylin and eosin techniques to examine arterial wall structures. Increased velocity time integral correlated with increased arterial medial thickness (r = 0.50, P&lt;0.01), arterial smooth muscle cells (r =0.43, P&lt;0.05) and arterial smooth muscle layers (r=0.45, P&lt;0.01). These relationships remained significant after controlling for body-mass index (BMI). Increased BMI was associated with increased velocity time integral (r=0.61, P&lt;0.01), arterial medial thickness (r=0.37, P&lt;0.05) and arterial medial area (r=0.36, P&lt;0.05). SpO2nadir (TST/REM) was inversely associated with arterial medial area (r=-0.35; r=-0.38, P&lt;0.05). These results demonstrate that increased blood flow velocity is associated with changes in arterial wall composition in children with SDB. This suggests that paediatric SDB, a treatable disorder, is potentially a modifiable risk factor for early vascular ageing and resultant cardiovascular disease in adulthood.


Author(s):  
Deepti Bodh ◽  
Mozammel Hoque ◽  
Abhishek Chandra Saxena

Background: Pulsed-wave Doppler measures blood flow at specific point and provides information on velocity, direction and uniformity of blood flow throughout cardiac cycle. Till date, there is no published data on study of cardiac parameters using pulsed-wave Doppler echocardiography in Indian Spitz dogs.Methods: Twenty-four clinically normal Indian Spitz dogs were subjected to pulsed-wave Doppler echocardiography to determine the reference intervals for Doppler parameters of blood flow through mitral, tricuspid and aortic valves. Mitral peak E and A-wave velocities, E/A ratio, deceleration time, isovolumic relaxation time, E and A-wave velocity time integral, E duration and A duration were 0.69±0.09 m/s, 0.43±0.12 m/s, 1.69±0.45, 111.25±35.94 ms, 48.50±24.77 ms, 0.07±0.01 m and 0.04±0.02 m, 196.88±44.38 ms and 181.25±64.89 ms, respectively. Tricuspid peak E and A-wave velocities, E/A ratio and E and A-wave velocity time integral were 0.57±0.11 m/s, 0.38±0.08 m/s, 1.56±0.32 and 0.07±0.02 m and 0.05±0.01 m, respectively. Aortic peak velocity, velocity time integral and ejection time were 0.87±0.07 m/s, 0.11±0.02 m and 0.25±0.04 s, respectively. Conclusion: The reference values of flow parameters across mitral, tricuspid and aortic valves using pulsed-wave Doppler echocardiography were determined. Mitral, tricuspid and aortic valve flow variables were unaffected by gender whereas isovolumic relaxation correlated positively with body weight.


2019 ◽  
pp. 102490791987092 ◽  
Author(s):  
Semih Korkut ◽  
Erden Erol Ünlüer ◽  
Arif Karagöz ◽  
Karama Bouchaala Mnif ◽  
Emine Kadioğlu

Purpose: In this study, we aimed to compare cardiac output, echocardiographic pulmonary velocity-time integral, and end-tidal carbon dioxide values before and after the passive leg raising maneuver in healthy volunteers. Methods: The Ethical Commission approved the study. A total of 36 volunteers were included after signed informed consent in our study. After 12 h of fasting, vital signs, cardiac output, pulmonary velocity-time integral, and end-tidal carbon dioxide were measured when the participants were lying supine. Then, participants’ legs were elevated to 45° passively, and all measurements were repeated. Pulmonary velocity-time integral was obtained in parasternal short-axis view with the aid of pulse Doppler. Pulmonary root measurements were recorded. Echocardiographic stroke volume and cardiac output were calculated. The differences between values of cardiac output, pulmonary velocity-time integral, and end-tidal carbon dioxide before and after passive leg raising were statistically compared. The level of significance was accepted as p < 0.05. Results: Significant differences were found between pre- and post-passive leg raising values of these three measurements. The effect of passive leg raising on pulmonary velocity-time integral measurements was greater. The change in end-tidal carbon dioxide was not correlated with either cardiac output or pulmonary velocity-time integral alteration. Conclusion: Our results showed that measurement of pulmonary velocity-time integral changes after passive leg raising is a more useful bedside method to predict fluid responsiveness than measurement of end-tidal carbon dioxide and cardiac output alteration.


2018 ◽  
Vol 23 (suppl_1) ◽  
pp. e16-e17
Author(s):  
Amit Mukerji ◽  
Abdul Gani Muzafar Wahab ◽  
Souvik Mitra ◽  
Tapas Mondal ◽  
Debie Paterson ◽  
...  

Abstract BACKGROUND Many NICUs employ high (>8 cmH2O) positive end-expiratory pressures (PEEP) on nasal continuous positive airway pressure (NCPAP) to prevent intubation and associated ventilator-induced lung injury, despite limited safety/efficacy data. OBJECTIVES This study sought to evaluate the physiological impact of high NCPAP PEEP. DESIGN/METHODS Fifteen preterm neonates at postmenstrual age ≥32 weeks (without congenital anomalies or acute intercurrent illness) on NCPAP PEEP of 5 cmH2O were enrolled. PEEP was increased by 2 cmH2O increments until 13 cmH2O. At each increment, following 5 minutes washout, cardiac output (aortic velocity-time integral x heart rate) and cardiorespiratory parameters including blood pressure, heart rate, respiratory rate were measured over 10 minutes. Predefined cut-off values for changes in cardiorespiratory parameters were used as termination criteria. Data are presented as mean (SD), and were compared using one-way ANOVA. RESULTS The mean GA, age at study, and weight of subjects were 27.4 (2.6) weeks, 58.5 (35.5) days, and 2.3 (0.6) kg, respectively. Cardiac output (mL/kg/min) at PEEPs of 5, 7, 9, 11, and 13 cmH2O were not different at 295 (75), 290 (66), 281 (69), 286 (73), and 292 (58), respectively (P=0.986), as shown in Figure 1a. Importantly there were also no differences in either aortic velocity-time integral or heart rate over these PEEP ranges (Figures 1b and 1c). There were no significant differences in cardiorespiratory parameters; no subjects met cut-off criteria. Data collection was terminated in 2 subjects after PEEP 9 cmH2O due to lung over-distension subjectively noted on echocardiogram. CONCLUSION High levels of NCPAP PEEP were well tolerated for short durations. Further physiological and clinical research is required on safety/efficacy in neonates with more severe lung disease, as well as its impact over longer durations.


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