Von Willebrand Factor, Type 2 Diabetes Mellitus, and Risk of Cardiovascular Disease: The Framingham Offspring Study

2009 ◽  
Vol 2009 ◽  
pp. 41-43
Author(s):  
G.L. Moneta
Circulation ◽  
2008 ◽  
Vol 118 (24) ◽  
pp. 2533-2539 ◽  
Author(s):  
David S. Frankel ◽  
James B. Meigs ◽  
Joseph M. Massaro ◽  
Peter W.F. Wilson ◽  
Christopher J. O'Donnell ◽  
...  

2016 ◽  
Vol 5 (81) ◽  
pp. 6075-6079 ◽  
Author(s):  
Umadevi B ◽  
Roopakala M S ◽  
Wilma Delphine Silvia C R ◽  
Prasanna Kumar K M

2020 ◽  
Vol 15 (6) ◽  
pp. 892-899 ◽  
Author(s):  
A. V. Zhito ◽  
A. O. Iusupova ◽  
E. V. Privalova ◽  
N. V. Khabarova ◽  
Yu. N. Belenkov

The prevalence of coronary heart disease (CHD) and type 2 diabetes mellitus (type 2 diabetes) in Russia and in the world continues to increase. Despite the prevention and optimization of therapy, CHD retains its leadership among all causes of death, and the mortality rate from type 2 diabetes and its complications gradually increases too. To improve the treatment of the above mentioned diseases, it is necessary to clarify the pathogenetic mechanisms of their development. The formation of endothelial dysfunction, characterized by an increase in the level of cell adhesion molecules and vasoconstriction, is a common link characteristic for the course and progression of CHD and type 2 diabetes. This article presents an analysis of preand clinical studies on the role of endothelial dysfunction markers: cell adhesion molecules (E-selectin), vasoconstriction (endothelin-1) and von Willebrand factor in patients with CHD, including those with type 2 diabetes mellitus.


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