Glutathione peroxidase-1 expression enhances recovery of human breast carcinoma cells from hyperoxic cell cycle arrest

2002 ◽  
Vol 33 (9) ◽  
pp. 1279-1289 ◽  
Author(s):  
Jean-François Bilodeau ◽  
Alexandre Patenaude ◽  
Bruno Piedboeuf ◽  
Caroline Carrier ◽  
Peter Petrov ◽  
...  
2002 ◽  
Vol 42 (1) ◽  
pp. 55-64 ◽  
Author(s):  
Chingwen Ying ◽  
Jih-Tay Hsu ◽  
Hsiao-Chiao Hung ◽  
Don-Hei Lin ◽  
Long-Fang Oliver Chen ◽  
...  

2016 ◽  
Vol 62 (3) ◽  
pp. 272-278 ◽  
Author(s):  
N.I. Kozlova ◽  
G.E. Morozevich ◽  
N.A. Ushakova ◽  
N.M. Gevorkian ◽  
A.E. Berman

In MCF-7/Dox human breast carcinoma cells, down-regulation of integrin alpha5beta1 and inhibition of epidermal growth factor receptor (EGFR) markedly reduced rates of cell proliferation. Mitotic cycle analysis showed that alpha5beta1 down-regulation resulted in cell cycle arrest at the S phase, followed by a significant increase in the population of apoptotic cells (subG1 population). Inhibition of EGFR activity also caused cell cycle arrest at the S-phase but without any increase in the subG1 population. Down-regulation of alpha5beta1 and EGFR inhibition resulted in a significant decrease of cell content of the active (phosphorylated) forms of FAK and Erk protein kinases. The data obtained suggest that alpha5beta1 integrin is implicated in cell growth control via inhibition of apoptotic cell death and through EGFR activation.


Oncogene ◽  
2001 ◽  
Vol 20 (36) ◽  
pp. 5043-5053 ◽  
Author(s):  
Reiner U Jänicke ◽  
Ingo H Engels ◽  
Torsten Dunkern ◽  
Bernd Kaina ◽  
Klaus Schulze-Osthoff ◽  
...  

2011 ◽  
Vol 35 (10) ◽  
pp. 1025-1029 ◽  
Author(s):  
Reelma Velho‑Pereira ◽  
Amit Kumar ◽  
Badri N. Pandey ◽  
Aarti G. Jagtap ◽  
Kaushala P. Mishra

2020 ◽  
Vol 47 (8) ◽  
pp. 6043-6051
Author(s):  
Fahd A. Nasr ◽  
Abdelaaty A. Shahat ◽  
Ali S. Alqahtani ◽  
Mohammad Z. Ahmed ◽  
Wajhul Qamar ◽  
...  

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