Effectiveness of bacillus calmette guerin (BCG) vaccination in the prevention of leprosy: A case control study in Nagpur, India

1998 ◽  
Vol 51 ◽  
pp. S18
Author(s):  
Sanjay P. Zodpey ◽  
S.N. Shrikhande ◽  
A.D. Salodkar ◽  
B.R. Maldhure ◽  
S.W. Kulkarni
2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Joaquim C. V. D. Van-Dunem ◽  
Laura C. Rodrigues ◽  
Luiz Claudio Arraes Alencar ◽  
Maria de Fátima Pessoa Militão-Albuquerque ◽  
Ricardo Arraes de Alencar Ximenes

The objective of this study was to estimate the protective effect of Bacille Calmette-Guérin (BCG) vaccine against tuberculosis among (predominantly immunodeficient) HIV-infected children in Angola. A hospital-based case-control study was conducted with 230 cases, children coinfected with tuberculosis, and 672 controls, HIV-infected children from the same hospital, aged 18 months to 13 years. The presence of a vaccination scar was taken as a proxy marker for BCG vaccination. The crude effectiveness was 8% (95% CI: −26 to 32) and the adjusted effectiveness was 30% (95% CI: −75 to 72). The present study suggests that BCG does not have a protective effect against tuberculosis among immunodeficient HIV-infected children. Since BCG is no longer given to HIV-infected children, the study may not be replicated. Accepting that these findings should be considered with caution, they are nonetheless likely to be the last estimate of BCG efficacy in a sufficiently powered study.


2018 ◽  
Vol 68 ◽  
pp. 01013
Author(s):  
Ayu Febri Wulanda ◽  
Rico Januar Sitorus ◽  
Zulkarnain

Bacillus Calmette Guerin (BCG) vaccine is still the only licensed vaccine against Tuberculosis (TB), with an estimated global coverage of 85%. However, although the vaccine has been established, discussions about its benefits and shortcomings continue.The coverage of immunization is appropriate with the target, but still the occurrence of child TB cases raises a problem of its own. This studywas a non-experimental study with study design was Case Control Study by retrospective. The effectiveness of BCG immunization in this study is 85%, meaning that children are given BCG 85% immunization will be protected from Tuberculocis (TB) disease. If the child does not get BCG immunization will increase the chances for the child, with OR = 6.87 (95% CI; 2.2 – 21.1) with p value = 0.000. It is suggested to Banyuasin regency Health Office to conduct the contact examination of house of children who are around TB positive patients periodically (monthly / at posyandu).


Tubercle ◽  
1986 ◽  
Vol 67 (4) ◽  
pp. 283-288 ◽  
Author(s):  
P. Blin ◽  
H.G. Delolme ◽  
J.D. Heyraud ◽  
Y. Charpak ◽  
L. Sentilhes

2015 ◽  
Vol 9 (1) ◽  
pp. e3457 ◽  
Author(s):  
Richard Odame Phillips ◽  
Delphin Mavinga Phanzu ◽  
Marcus Beissner ◽  
Kossi Badziklou ◽  
Elysée Kalundieko Luzolo ◽  
...  

2000 ◽  
Vol 17 (7) ◽  
pp. 541-550 ◽  
Author(s):  
Rüdiger Von Kries ◽  
Veit Peter Grunert ◽  
Uwe Kaletsch ◽  
Jörg Michaelis ◽  
Ulrich Göbel

Sign in / Sign up

Export Citation Format

Share Document