scholarly journals Blood pressure response to exercise in normotensive young men with or without family history of hypertension

2001 ◽  
Vol 14 (11) ◽  
pp. A201
Author(s):  
M Biagini
Keyword(s):  
Blood Pressure ◽  
Family History ◽  
Blood Pressure Response ◽  
Young Men ◽  
Pressure Response ◽  
History Of ◽  
Family History Of Hypertension ◽  
Response To Exercise

Abstract 2552: Hypertrophic Cardiomyopathy in Children: Do Adult Risk Factors for Cardiac Death Apply

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Jamie A Decker ◽  
Joseph W Rossano ◽  
E. O’Brian Smith ◽  
Bryan C Cannon ◽  
Sarah K Clunie ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Hypertrophic Cardiomyopathy ◽  
Family History ◽  
Blood Pressure Response ◽  
Left Ventricular ◽  
Pressure Response ◽  
Systemic Hypertension ◽  
Response To Exercise

Introduction : Annual mortality in children with hypertrophic cardiomyopathy (HCM) has been reported to be 1– 6%. Risk factors for death in adult HCM patients have been characterized; their application to pediatric HCM is unknown. The purpose of this study was to correlate adult risk factors with outcomes in our pediatric population using a standard management strategy. Methods : A retrospective cohort study of children with HCM was performed. Death and cardiac transplant were the primary outcomes. Diagnosis was based on asymmetric septal or concentric hypertrophy as determined by echocardiography. Exclusion criteria included: genetic syndrome, mitochondrial or metabolic disorder, infants of diabetic mothers, congenital heart disease, systemic hypertension, diagnosis >18 years of age, or follow-up <1 year. Results : From 1/1/85 to 10/1/06, 96 patients met inclusion criteria. Mean age at diagnosis was 10.6 ± 5.4 years. Mean follow-up was 6.5 ± 5.2 years. 11 patients had an adverse outcome (7 deaths, 4 transplants). Kaplan-Meier analysis predicts an 82% survival over 20 years. Evidence of left ventricular outflow tract obstruction (LVOTO) occurred in =6% of patients, syncope in 23% and a family history for malignant HCM in 17%. Aborted sudden death occurred in 6%. 10% had non-sustained ventricular tachycardia. 58% of patients underwent at least one exercise treadmill test. All patients were restricted from strenuous activity. 95% of patients were on a β-blocker or calcium channel blocker, with 10% on both. Additional intervention depended on symptoms, family history, and degree of LVOTO. 17% had an implantable defibrillator (ICD). 10% were given a pacemaker due to LVOTO, and 5% underwent left ventricular myectomy. Only extreme LVH (>6 z-scores for BSA) and a blunted blood pressure response to exercise were statistically significant for worse outcomes (both p<0.02). Conclusions : A low mortality/transplantation rate occurred in children with isolated HCM whose management consisted of exercise restriction and medication, with or without an ICD. Management that included myectomy was uncommon. Patients with extreme LVH and a blunted blood pressure response to exercise are high-risk individuals.

Different Haemodynamic Reaction Patterns during Noise Exposure in Normotensive Subjects with and without Heredity for Essential Hypertension

1982 ◽  
Vol 63 (s8) ◽  
pp. 371s-374s ◽  
Author(s):  
L. Andrén ◽  
S. Piros ◽  
L. Hansson ◽  
H. Herlitz ◽  
O. Jonsson
Keyword(s):  
Blood Pressure ◽  
Family History ◽  
Noise Exposure ◽  
Blood Pressure Response ◽  
Positive Family History ◽  
Peripheral Resistance ◽  
Sodium Concentration ◽  
History Of ◽  
Family History Of Hypertension ◽  
Normotensive Subjects

1. Stimulation with noise (100 dBA) for 10 min caused a significant increase in diastolic and mean arterial pressure in normotensive subjects with and without a positive family history of hypertension. 2. The blood pressure response in the group with a positive family history of hypertension was due to a significant increase in total peripheral resistance (9%, P < 0.05); no such change was seen in the group without heredity for hypertension. 3. Systolic blood pressure, heart rate, stroke volume and cardiac output did not change significantly during exposure to noise. 4. There was no difference between the groups in mean intracellular sodium concentration measured in erythrocytes.

FEATURES OF ARTERIAL PRESSURE RESPONSE TO EXERCISE TESTS IN ATHLETES OF VARIOUS SPORTS

2020 ◽  
Vol 8 (1) ◽  
pp. 62-68
Author(s):  
Fanis Mavliev ◽  
Andrey Nazarenko ◽  
Rustam Asmanov ◽  
Ajdar Sirazetdinov ◽  
Artem Mastrov
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Exercise Test ◽  
Blood Pressure Response ◽  
Young Men ◽  
Pressure Response ◽  
Exercise Tests ◽  
Load Increase ◽  
Pressure Indicators ◽  
Response To Exercise

The aim – analysis of short and long-term blood pressure responses to exercise test in young people involved in various sports. Materials and methods. The study involved athletes ranked from Third-Class athletes to the Master of Sports of the Russian Federation. During exercise tests, we used the following ergometers and load protocols to simulate various physical activity: Cosmos quasar treadmill – speed increase by 1 km/h per minute; e-Bike Bicycle Ergometer – load increase by 15 watts/min; Concept 2 rowing ergometer – 30W load increase every two minutes. Results. The research revealed that the blood pressure response to exercise tests in the studied groups of young men depended little on weight and height indicators because there were practically no overweight persons among active athletes. Pulse pressure (PP) is a genetic factor. In this regard, blood pressure indicators of young men are higher at rest and after exercise tests than blood pressure indicators of girls. When considering indicators without gender differentiation, rowing was the most distinctive sport in terms of indicators of blood pressure response to exercises tests. We recorded the lowest values of diastolic pressure after rowing activity. In our opinion, this follows from the fact that the «global vasodilation» effect leads to a short-term blood pressure drop (on average by 6 mm Hg) after exercise test. This is expressed in statistically significant DP differences (p<0,05) before and after exercise test in rowers compared to athletes involved in other sports. Conclusion. Indices of blood pressure at rest and after physical activity depend on gender factors and kinds of sport. At the same time, rowers demonstrated the most distinctive data. We can explain it both by the number of muscles involved in motor activity and by the specifics of execution (body position).

Blood Pressure and Intra-Erythrocyte Sodium during Normal and High Salt Intake in Middle-Aged Men: Relationship to Family History of Hypertension, and Neurogenic and Hormonal Variables

1984 ◽  
Vol 66 (4) ◽  
pp. 427-433 ◽  
Author(s):  
Ottar Gudmundsson ◽  
Hans Herlitz ◽  
Olof Jonsson ◽  
Thomas Hedner ◽  
Ove Andersson ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Family History ◽  
Salt Intake ◽  
Sodium Intake ◽  
Positive Family History ◽  
Sodium Content ◽  
High Salt Intake ◽  
History Of ◽  
Family History Of Hypertension ◽  
Erythrocyte Sodium

1. During 4 weeks 37 normotensive 50-year-old men identified by screening in a random population sample were given 12 g of NaCl daily, in addition to their usual dietary sodium intake. Blood pressure, heart rate, weight, urinary excretion of sodium, potassium and catecholamines, plasma aldosterone and noradrenaline and intra-erythrocyte sodium content were determined on normal and increased salt intake. The subjects were divided into those with a positive family history of hypertension (n = 11) and those without such a history (n = 26). 2. Systolic blood pressure and weight increased significantly irrespective of a positive family history of hypertension. 3. On normal salt intake intra-erythrocyte sodium content was significantly higher in those with a positive family history of hypertension. During high salt intake intra-erythrocyte sodium content decreased significantly in that group and the difference between the hereditary subgroups was no longer significant. 4. In the whole group urinary excretion of noradrenaline, adrenaline and dopamine increased whereas plasma aldosterone decreased during the increased salt intake. 5. Thus, in contrast to some earlier studies performed in young subjects, our results indicate that moderately increased sodium intake acts as a pressor agent in normotensive middle-aged men whether there was a positive family history of hypertension or not. We confirm that men with positive family history of hypertension have an increased intra-erythrocyte sodium content, and that an increase in salt intake seems to increase overall sympathetic activity.

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