O254 Mediterranean spotted fever: a reemerging rickettsiosis? New trends in epidemiology, ecology and clinical presentation

2007 ◽  
Vol 29 ◽  
pp. S50
Author(s):  
C. Rovery ◽  
N. Mouffok ◽  
P.-E. Fournier ◽  
P. Brouqui ◽  
D. Raoult
Keyword(s):  
Clinical Presentation ◽  
Spotted Fever ◽  
Mediterranean Spotted Fever

scholarly journals Unusual Maculopapular Rash on the Scalp of a Patient with Mediterranean Spotted Fever

2018 ◽  
Vol 28 (3) ◽  
pp. 291-293
Author(s):  
Ivan Baltadzhiev ◽  
Nedialka Popivanova
Keyword(s):  
Breast Cancer ◽  
Clinical Features ◽  
Rare Case ◽  
Clinical Characteristics ◽  
Clinical Presentation ◽  
Spotted Fever ◽  
Good Condition ◽  
Maculopapular Rash ◽  
Mediterranean Spotted Fever ◽  
Immunofluorescent Assay

Objective: To report a rare case of maculopapular rash on the scalp in a patient with Mediterranean spotted fever (MSF). Clinical Presentation and Intervention: A 58-year-old woman with breast cancer and chemotherapy-induced alopecia contracted MSF. Her clinical features were typical, except for a maculopapular rash covering the scalp. The diagnosis of MSF was confirmed by immunofluorescent assay. The disease had a favorable course and the patient was discharged in good condition. Conclusion: The rash on the scalp described in this report enriches our knowledge on the clinical characteristics of MSF.

Persistent Fever and Exanthema in a Family: A Case Report of Mediterranean Spotted Fever

2005 ◽  
Vol 12 (2) ◽  
pp. 91-94
Author(s):  
CP Ng ◽  
CH Chung
Keyword(s):  
Clinical Presentation ◽  
Early Recognition ◽  
Spotted Fever ◽  
Common Disease ◽  
Mediterranean Spotted Fever ◽  
Notifiable Disease ◽  
Persistent Fever ◽  
Boutonneuse Fever ◽  
Disease Vector ◽  
History Of

Mediterranean spotted fever (also called Boutonneuse fever) is a notifiable disease in Hong Kong, but its diagnosis can be difficult. We report a case of Mediterranean spotted fever in a middle-aged man who presented with persistent fever, headache, and skin rash. Three weeks ago, his daughter had similar presentations. With a history of similar clinical presentation within family members, the possibility of potential exposure to a common disease vector should be suspected. Establishing an early diagnosis may be possible if this important history is obtained. Early recognition of this disease may lead to early therapeutic intervention, resulting in decreased morbidity and shortened duration of hospital stay.

scholarly journals Tache Noire in a Patient with Acute Q Fever

2018 ◽  
Vol 27 (1) ◽  
pp. 92-94
Author(s):  
Vito Fiore ◽  
Fabiola Mancini ◽  
Alessandra Ciervo ◽  
Paola Bagella ◽  
Francesca Peruzzu ◽  
...  
Keyword(s):  
Rare Case ◽  
Clinical Presentation ◽  
Q Fever ◽  
Spotted Fever ◽  
Mediterranean Area ◽  
Clinical Feature ◽  
Mediterranean Spotted Fever ◽  
Acute Q Fever ◽  
Pathognomonic Sign ◽  
Rule Out

Objective: To describe a rare case of acute Q fever with tache noire. Clinical Presentation and Intervention: A 51-year-old man experienced acute Q fever showing tache noire, generally considered a pathognomonic sign of Mediterranean spotted fever (MSF) and MSF-like illness, but not a clinical feature of Q fever. The patient was treated with doxycycline 100 mg every 12 h. Conclusion: In the Mediterranean area, tache noire should be considered pathognomonic of MSF but it should not rule out Q fever. Clinical diagnosis should be supported by accurate laboratory diagnostic tests to guide proper management.

scholarly journals Mediterranean Spotted Fever in Central Tunisia

1994 ◽  
Vol 1 (2) ◽  
pp. 106-108 ◽  
Author(s):  
Letaïef Jemni ◽  
Houssem Hmouda ◽  
Mohamed Chakroun ◽  
Moez Ernez ◽  
Mezri May
Keyword(s):  
Spotted Fever ◽  
Mediterranean Spotted Fever ◽  
Central Tunisia

IMMUNOLOGICAL STUDIES IN MEDITERRANEAN SPOTTED FEVER

The Lancet ◽  
1982 ◽  
Vol 319 (8283) ◽  
pp. 1249 ◽  
Author(s):  
M.A. Piras ◽  
C. Gakis ◽  
M. Budroni ◽  
G. Andreoni
Keyword(s):  
Spotted Fever ◽  
Mediterranean Spotted Fever

scholarly journals Assessment of the Percentages of T-lymphocyte Subsets in the Peripheral Blood of Mediterranean Spotted Fever Patients

2020 ◽  
Vol 18 (2) ◽  
pp. 111-119
Author(s):  
Iv. Baltadzhiev ◽  
P. Pavlov
Keyword(s):  
T Cells ◽  
Disease Severity ◽  
T Lymphocyte ◽  
Lymphocyte Subsets ◽  
Spotted Fever ◽  
Healing Process ◽  
Cell Subset ◽  
Rickettsia Conorii ◽  
Mediterranean Spotted Fever ◽  
T Lymphocyte Subsets

Purpose: Mediterranean spotted fever (MSF) is a rickettsial disease. The aim was to evaluate the host immunе response to Rickettsia conorii. Material and methods: 62 patients were assigned into three groups: with mild, moderate or severe clinical forms of MSF. Controls were 32 healthy individuals. The diagnosis of MSF was confirmed by the indirect immunofluorescence assay. Immunophenotyping was performed using Epics XL-MCL Coulter. Results: The percentage of immune competent (CD3+) cells decreased, whereas that of helper/inducer (CD3+CD4+) and suppressor/cytotoxic (CD3+CD8+) did not change compared to controls. All three T-cell subset percentages did not parallel the disease severity. Naïve T-cells (CD4+CD45RA+) showed reduced levels, whereas activated memory (CD4+CD45RO+) T-cells did not change significantly. The percentage of activated (CD3+HLA-DR+) T-cells increased regardless of the disease severity, till the rise of stimulatory molecules (CD38+total) matched the disease severity forms. The percentage of costimulatory CD28-molecules corresponded to the disease severity as their levels increased significantly in mild forms and showed an evident downward trend towards the severe ones. Conclusion: Reduced T-lymphocyte subsets are likely related to trans-migration into perivascular inflammatory foci. The increased percentage of T-lymphocytes armed with stimulatory molecules probably reflects the mobilization of cell-mediated immune response in the healing process.

Mediterranean spotted fever in Salamanca, Spain. Epidemiological study in patients and serosurvey in animals and healthy human population

Acta Tropica ◽  
1989 ◽  
Vol 46 (5-6) ◽  
pp. 335-350 ◽  
Author(s):  
JoséIgnacio Herrero-Herrero ◽  
Ricardo Ruiz-Beltrán ◽  
A.Manuel Martín-Sánchez ◽  
Enrique J. García
Keyword(s):  
Epidemiological Study ◽  
Human Population ◽  
Spotted Fever ◽  
Mediterranean Spotted Fever ◽  
Healthy Human
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