Comparison of Clinical Characteristics of Generalized Anxiety Disorder Between Turkish Immigrants, Native Turkish and German Patients

BackgroundThe nosological status of generalized anxiety disorder (GAD) versus dysthymic disorder (DD) has been questioned. The aim of this study was to examine qualitative differences within (co-morbid) GAD and DD symptomatology.MethodLatent class analysis was applied to anxious and depressive symptomatology of respondents from three population-based studies (2007 Australian National Survey of Mental Health and Wellbeing; National Comorbidity Survey Replication; and Netherlands Mental Health Survey and Incidence Study-2; together known as the Triple study) and respondents from a multi-site naturalistic cohort [Netherlands Study of Depression and Anxiety (NESDA)]. Sociodemographics and clinical characteristics of each class were examined.ResultsA three-class (Triple study) and two-class (NESDA) model best fitted the data, reflecting mainly different levels of severity of symptoms. In the Triple study, no division into a predominantly GAD or DD co-morbidity subtype emerged. Likewise, in spite of the presence of pure GAD and DD cases in the NESDA sample, latent class analysis did not identify specific anxiety or depressive profiles in the NESDA study. Next, sociodemographics and clinical characteristics of each class were examined. Classes only differed in levels of severity.ConclusionsThe absence of qualitative differences in anxious or depressive symptomatology in empirically derived classes questions the differentiation between GAD and DD.

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Dose the Clinical Characteristics of Patients with Anxiety due to Hyperthyroidism Differ from Patients with Generalized Anxiety Disorder? A Comparative Study

Iranian Journal of Psychiatry and Behavioral Sciences ◽

10.5812/ijpbs.4812 ◽

2016 ◽

Vol 11 (1) ◽

Author(s):

Arash Mowla ◽

Mohammad Reza Kalantarhormozi ◽

Samane Khazraee

Keyword(s):

Anxiety Disorder ◽

Comparative Study ◽

Generalized Anxiety Disorder ◽

Clinical Characteristics ◽

Generalized Anxiety

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Screening of Generalized Anxiety Disorder in Patients with Epilepsy: Using a Valid and Reliable Indonesian Version of Generalized Anxiety Disorder-7 (GAD-7)

Neurology Research International ◽

10.1155/2019/5902610 ◽

2019 ◽

Vol 2019 ◽

pp. 1-10 ◽

Cited By ~ 2

Author(s):

Astri Budikayanti ◽

Andira Larasari ◽

Khamelia Malik ◽

Zakiah Syeban ◽

Luh Ari Indrawati ◽

...

Keyword(s):

Anxiety Disorder ◽

Generalized Anxiety Disorder ◽

Predictive Value ◽

Clinical Characteristics ◽

Screening Tool ◽

World Health ◽

Generalized Anxiety ◽

Validity And Reliability ◽

Cross Sectional ◽

Patients With Epilepsy

Introduction. Generalized anxiety disorder (GAD) is one of the most common types of anxiety disorder in epilepsy population, comprising 21.9%, that would further impair patients’ quality of life. Generalized Anxiety Disorder-7 (GAD-7) is the only screening tool for GAD that has been validated in patients with epilepsy (PWE). It is a self-reporting instrument that can be completed in less than three minutes; hence, its usage is appropriate in primary healthcare and neurology outpatient clinic. This study aimed to obtain a valid and reliable Indonesian version of GAD-7, assess its accuracy, and finally evaluate the prevalence of GAD in Indonesian PWE along with its contributing factors. Methods. A cross-sectional study was conducted in Cipto Mangunkusumo General Hospital, Jakarta. The GAD-7 was translated and adapted using World Health Organization (WHO) steps. Validity, reliability, test-retest reliability, and diagnostic accuracy were evaluated. Then, epilepsy outpatients were screened for GAD using the Indonesian version of GAD-7. Results. Internal validity and reliability for Indonesian version of GAD-7 were satisfactory with validity coefficient of 0.648 to 0.800 (p<0.01) and Cronbach’s alpha value of 0.867. The best cutoff value to detect GAD in Indonesian PWE was >6 with the sensitivity, specificity, negative predictive value, and positive predictive value of 100%, 84.4%, 100%, and 55.8%, respectively. ROC analysis showed the area under the curve of 0.98 (95% CI: 0.96–0.99). The total subjects screened with the validated Indonesian version of GAD-7 were 146, and 49% were screened as having GAD. Sociodemographic and clinical characteristics had no statistically significant association with the presence of GAD. Conclusion. The Indonesian version of GAD-7 was a valuable screening tool to detect GAD in PWE. GAD was screened in a quite high proportion of PWE. Sociodemographic and clinical characteristics were not proven to play role in its development.

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Generalized anxiety disorder in type 2 diabetes mellitus: prevalence and clinical characteristics

Brazilian Journal of Psychiatry ◽

10.1590/1516-4446-2019-0605 ◽

2020 ◽

Vol 42 (6) ◽

pp. 621-629 ◽

Cited By ~ 2

Author(s):

Chun-Jen Huang ◽

Hui-Min Hsieh ◽

Hung-Pin Tu ◽

He-Jiun Jiang ◽

Peng-Wei Wang ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Anxiety Disorder ◽

Generalized Anxiety Disorder ◽

Clinical Characteristics ◽

Generalized Anxiety

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Threshold and subthreshold generalized anxiety disorder among US adolescents: prevalence, sociodemographic, and clinical characteristics

Psychological Medicine ◽

10.1017/s0033291713002997 ◽

2014 ◽

Vol 44 (11) ◽

pp. 2351-2362 ◽

Cited By ~ 18

Author(s):

M. Burstein ◽

K. Beesdo-Baum ◽

J.-P. He ◽

K. R. Merikangas

Keyword(s):

Anxiety Disorder ◽

Generalized Anxiety Disorder ◽

Clinical Characteristics ◽

Clinical Course ◽

Generalized Anxiety ◽

Face To Face ◽

Age Related ◽

Co Morbidity ◽

Associated Symptoms ◽

Nationally Representative

BackgroundThreshold and subthreshold forms of generalized anxiety disorder (GAD) are highly prevalent and impairing conditions among adults. However, there are few general population studies that have examined these conditions during the early life course. The primary objectives of this study were to: (1) examine the prevalence, and sociodemographic and clinical characteristics of threshold and subthreshold forms of GAD in a nationally representative sample of US youth; and (2) test differences in sociodemographic and clinical characteristics between threshold and subthreshold forms of the disorder.MethodThe National Comorbidity Survey-Adolescent Supplement is a nationally representative face-to-face survey of 10 123 adolescents 13 to 18 years of age in the continental USA.ResultsApproximately 3% of adolescents met criteria for threshold GAD. Reducing the required duration from 6 months to 3 months resulted in a 65.7% increase in prevalence (5.0%); further relaxing the uncontrollability criterion led to an additional 20.7% increase in prevalence (6.1%). Adolescents with all forms of GAD displayed a recurrent clinical course marked by substantial impairment and co-morbidity with other psychiatric disorders. There were few significant differences in sociodemographic and clinical characteristics between threshold and subthreshold cases of GAD. Results also revealed age-related differences in the associated symptoms and clinical course of GAD.ConclusionsFindings demonstrate the clinical significance of subthreshold forms of GAD among adolescent youth, highlighting the continuous nature of the GAD construct. Age-related differences in the associated symptoms and clinical course of GAD provide further support for criteria that capture variation in clinical features across development.

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