Lamotrigine demonstrates long-term mood stabilization in bipolar patients with recent episode of mania or hypomania

2001 ◽  
Vol 11 ◽  
pp. S206 ◽  
Author(s):  
J. Calabrese ◽  
S. Montgomery ◽  
S. Akhtar ◽  
M. Hompland ◽  
M. Olajossy ◽  
...  
Keyword(s):  
Mood Stabilization ◽  
Bipolar Patients

Self-esteem in Recovered Bipolar and Unipolar Out-patients

1993 ◽  
Vol 163 (6) ◽  
pp. 755-762 ◽  
Author(s):  
D. Pardoen ◽  
F. Bauwens ◽  
A. Tracy ◽  
F. Martin ◽  
J. Mendlewicz
Keyword(s):  
Social Adjustment ◽  
Clinical Characteristics ◽  
Self Esteem ◽  
Normal Control Group ◽  
Basic Component ◽  
Control Group ◽  
Bipolar Patients ◽  
The Relationship ◽  
Depressive Patients

The hypothesis of a low self-esteem in depressive patients was tested using the Rosenberg Self-Esteem Scale in 24 recovered unipolar and 27 recovered bipolar patients, compared with a normal control group of 26 subjects matched for age and sex. The hypothesis was confirmed only for unipolars; bipolar patients presented a self-esteem score not significantly different from normal scores. Self-esteem was not related to clinical characteristics of the affective disorder, suggesting that low self-esteem may be a basic component of a depression-prone personality. The investigation of the relationship between self-esteem and social adjustment confirmed the presence of social conformism in bipolar patients and rigidly set low self-esteem in unipolar patients. These results should stimulate the evaluation of different psychotherapeutic treatments in the long-term psychosocial management of affectively ill patients.

Treatment of Rapid-Cycling Bipolar Disorder

CNS Spectrums ◽  
2004 ◽  
Vol 9 (S2) ◽  
pp. 1-4
Author(s):  
Robert M. Post ◽  
Kiki D. Chang ◽  
Trisha Suppes ◽  
David L. Ginsberg
Keyword(s):  
Bipolar Disorder ◽  
Treatment Guidelines ◽  
Antidepressant Treatment ◽  
Rapid Cycling ◽  
Controlled Clinical Trials ◽  
Safety Considerations ◽  
Bipolar Patients ◽  
Patients Experience ◽  
Patient Use

AbstractApproximately 40% of bipolar patients experience rapid cycling, and half of these suffer from ultra-rapid or ultradian cycling. These patterns are also common in children. Rapid-cycling bipolar disorder is difficult to bring to remission and often requires treatment with four or more classes of psychotropic medications. Lithium, even in combination with anticonvulsants or antidepressants, is often associated with residual episodic depressions. Concerns with adjunctive antidepressant treatment include their low response and remission rates and their tendency to cause switch into mania. Atypical antipsychotics and selected agents within the anticonvulsant class are becoming increasingly important in the treatment of rapid cycling. In the absence of clear treatment guidelines, the use and sequencing of drugs in complex combination treatment remains exploratory, but should be individualized based on careful prospective mood charting by the patient. Use of several drugs below their side-effect thresholds may prevent certain side effects. In children, long-term safety considerations are particularly important in the absence of a strong controlled clinical trials database.

P.2.g.005 A long term prospective study of mixed bipolar patients

2009 ◽  
Vol 19 ◽  
pp. S474
Author(s):  
A. González-Pinto ◽  
M.A. Jimeno ◽  
M. Gutiérrez ◽  
K. Haidar ◽  
M. Sainz
Keyword(s):  
Prospective Study ◽  
Bipolar Patients

Thyroid structure and function in long‐term lithium‐treated and lithium‐naïve bipolar patients

2019 ◽  
Author(s):  
Agnieszka Kraszewska ◽  
Katarzyna Ziemnicka ◽  
Katarzyna Jończyk‐Potoczna ◽  
Jerzy Sowiński ◽  
Janusz K. Rybakowski
Keyword(s):  
Structure And Function ◽  
Bipolar Patients ◽  
And Function

Poor Long-Term Prognosis in Mixed Bipolar Patients

2010 ◽  
Vol 72 (05) ◽  
pp. 671-676 ◽  
Author(s):  
Ana González-Pinto ◽  
Sara Barbeito ◽  
Marta Alonso ◽  
Susana Alberich ◽  
Mahmoud Karim Haidar ◽  
...  
Keyword(s):  
Long Term Prognosis ◽  
Bipolar Patients

Decreased leukocyte telomere length in male patients with chronic bipolar disorder: lack of effect of long-term lithium-treatment

2021 ◽  
pp. 1-25
Author(s):  
Ewa Ferensztajn-Rochowiak ◽  
Ewa Kurczewska ◽  
Błażej Rubiś ◽  
Michalina Lulkiewicz ◽  
Hanna Hołysz ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Telomere Length ◽  
Lithium Treatment ◽  
Quantitative Polymerase Chain Reaction ◽  
Accelerated Aging ◽  
Control Group ◽  
Duration Of Treatment ◽  
Control Male ◽  
Bipolar Patients

Abstract Objectives: Bipolar disorder (BD) may be connected with accelerated aging, the marker of this can be shorter telomere length (TL). Some data suggest that lithium may exert a protective effect against telomere shortening. The study aimed to compare the telomere length between patients with bipolar disorder and control subjects. The effect of long-term lithium treatment was also assessed. Methods: The study group comprised 41 patients with BD, including 29 patients treated longitudinally with lithium (mean 16.5 years) and 20 healthy people. Telomere length was assessed by the quantitative polymerase chain reaction (qPCR). Results: In the control group, the TL was significantly longer in males than in females. Male bipolar patients had significantly shorter TL compared with the control male group. In bipolar patients, there was no correlation between TL and duration of treatment. The TL was negatively correlated with age in male bipolar patients. Conclusion: The study did not confirm the lithium effect on TL in bipolar patients. TL showed gender differences, being shorter in BD males, compared to control males, and longer in healthy males, compared to control females.

Recurrent Unipolar Manic Disorder in the Yoruba Nigerian: Further Evidence

1985 ◽  
Vol 147 (4) ◽  
pp. 434-437 ◽  
Author(s):  
Roger O. A. Makanjuola
Keyword(s):  
Bipolar Disorder ◽  
Clinical Presentation ◽  
Social Data ◽  
Manic Disorder ◽  
Western Countries ◽  
Bipolar Group ◽  
Female Sex ◽  
Depot Neuroleptics ◽  
Bipolar Patients

One hundred and four Yoruba Nigerian patients are described who presented with manic disorder over a five-year period; 55 could be classified as suffering from recurrent unipolar manic disorder, while 36 had suffered only one attack of mania. Only 13 patients suffered from bipolar disorder, in contrast to studies from Western societies, in which bipolar disorder is much more common than unipolar. The unipolar manic and bipolar patients could not be differentiated on the basis of clinical and social data, apart from a possible preponderance of the female sex in the bipolar group. The clinical presentation of mania was similar to that described from Western Countries. Long-term prophylaxis with depot neuroleptics may be advisable in such cases.

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