P.2.005 Successful use of risperidone in an adult with the pervasive developmental disorder, Asperger's syndrome: a case report

2003 ◽  
Vol 13 ◽  
pp. S281
Author(s):  
S. Raheja ◽  
S. Libretto ◽  
I. Singh
1990 ◽  
Vol 157 (2) ◽  
pp. 284-287 ◽  
Author(s):  
Ian Paul Everall ◽  
Ann Lecouteur

Firesetting in children and adolescents is commonly associated with other antisocial acts that comprise conduct disorders. Asperger's syndrome is a rare pervasive developmental disorder. In the case presented we argue that the firesetting arose from the disabilities inherent in Asperger's syndrome. This also indicates that antisocial acts may be symptoms in other psychiatric syndromes as well as a specific conduct disorder.


2011 ◽  
Vol 6 ◽  
pp. BMI.S7286 ◽  
Author(s):  
A.J. Russo ◽  
Robert deVito

Aim To assess plasma zinc and copper concentration in individuals with Asperger's Syndrome, Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS) and autistic disorder, and to analyze the efficacy of zinc therapy on the normalization of zinc and copper levels and symptom severity in these disorders. Subjects and methods Plasma from 79 autistic individuals, 52 individuals with PDD-NOS, 21 individuals with Asperger's Syndrome (all meeting DSM-IV diagnostic criteria), and 18 age and gender similar neurotypical controls, were tested for plasma zinc and copper using inductively-coupled plasma-mass spectrometry. Results Autistic and PDD-NOS individuals had significantly elevated plasma levels of copper. None of the groups (autism, Asperger's or PDD-NOS) had significantly lower plasma zinc concentrations. Post zinc and B-6 therapy, individuals with autism and PDD-NOS had significantly lower levels of copper, but individuals with Asperger's did not have significantly lower copper. Individuals with autism, PDD-NOS and Asperger's all had significantly higher zinc levels. Severity of symptoms decreased in autistic individuals following zinc and B-6 therapy with respect to awareness, receptive language, focus and attention, hyperactivity, tip toeing, eye contact, sound sensitivity, tactile sensitivity and seizures. None of the measured symptoms worsened after therapy. None of the symptoms in the Asperger's patients improved after therapy. Discussion These results suggest an association between copper and zinc plasma levels and individuals with autism, PDD-NOS and Asperger's Syndrome. The data also indicates that copper levels normalize (decrease to levels of controls) in individuals with autism and PDD-NOS, but not in individuals with Asperger's. These same Asperger's patients do not improve with respect to symptoms after therapy, whereas many symptoms improved in the autism group. This may indicate an association between copper levels and symptom severity.


1986 ◽  
Vol 148 (6) ◽  
pp. 731-736 ◽  
Author(s):  
Jacob Kerbeshian ◽  
Larry Burd

We review the English-language literature on Asperger's syndrome (AS), with particular reference to diagnostic criteria and differentiation from infantile autism and personality disorders, and describe six cases seen in practice; all met DSM-III criteria for ‘atypical pervasive developmental disorder’. Three also developed Tourette syndrome: the co-occurrence of the two disorders, and methods of intervention, are discussed.


1995 ◽  
Vol 77 (1) ◽  
pp. 207-210 ◽  
Author(s):  
Jeffrey A. Atlas ◽  
Ginny Gerbino-Rosen

A study of a l6.8-yr.-old female is presented to highlight aspects of Asperger's Syndrome as distinguished from cognate developmental and mood disorders. Brief therapy and pharmacological implications are mentioned.


1993 ◽  
Vol 4 (3) ◽  
pp. 555-562 ◽  
Author(s):  
Paul Chesterman ◽  
Susan C. Rutter

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