P.2.092 Quality of life and cognitive functions in schizophrenia

Gliomas make up about 8 cases per 100,000 population and the number of patients with this disease is only increasing. There can be not only various types of neurological deficits among the symptoms, but also personal and emotional changes, that seriously affects the quality of life. The modern model of health care includes not only recovery of the patient’s physical functions, but also his or her psychosocial well-being. In particular, the assessment and study of the characteristics of health-related quality of life, as well as cognitive functions in patients with gliomas, is increasingly recognized as an important criterion when considering the effectiveness of treatment. To date, the features of health related quality of life and cognitive functions of patients with epilepsy and acute cerebral circulation disorders have been studied sufficiently, and, as a result, techniques have been developed that accurately assess the QOL and CF in patients with these diseases. These are QOLIE-31 and QOLIE-AD-48 questionnaires for patients with epilepsy. This is the National Institutes of Health Stroke Scale (NIHSS), Orgogozo stroke scale (OSS), World Federation of Neurological Surgeons (WFNS) scale for the clinical assessment of subarachnoid hemorrhage (SAH) for patients with acute cerebrovascular accident. At the same time, there are no generally accepted methods for assessing quality of life and neurocognitive functions that are sensitive to changes in the condition of patients with gliomas in the early postoperative period by the time of discharge from the hospital. As a result, there is no systematic information on the dynamics of the quality of life of such patients, their neurocognitive functioning. The purpose of this article was to study the literature on QOL and CF in patients affected by neurological and neurosurgical disorders for the further selection of optimal methods for assessing dynamics of the condition of patients with glial brain tumors before and after surgery. At the moment, such requirements are only partially met by the EORTC QLQ-C30 questionnaire and its application EORTC QLQ-BN20.

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QUALITY-OF-LIFE STUDY IN PATIENTS WITH METABOLIC SYNDROME AND COGNITIVE DISORDERS

Bulletin Biomedicine and sociology ◽

10.26787/nydha-2618-8783-2021-6-1-13-22 ◽

2021 ◽

pp. 13-22

Author(s):

Zueva I.B. ◽

Yushkova I.D. ◽

Makarenko S.V. ◽

Kim Y.V.

Keyword(s):

Quality Of Life ◽

Metabolic Syndrome ◽

Physical Functioning ◽

Cognitive Functions ◽

Test Score ◽

Neuropsychological Testing ◽

Strong Association ◽

Cognitive Disorders ◽

Aged Patients

Nowadays, there is a tendency for an increasing prevalence of metabolic syndrome (MS) among middle-aged patients. It seems relevant to determine the quality of life in patients with MS and cognitive impairment (CI) in this age group. Aim of the study. Studying the quality of life in patients with MS and CI. Material and methods. In total, 208 people were examined. Out of a total number, 178 patients were divided into 2 groups: some were diagnosed with MS and CI, and some patients had MS but no cognitive deficit. The comparison group consisted of 30 healthy individuals of comparable age. All patients underwent neuropsychological testing. The method of cognitive evoked potential (P300) with the use of EMG/VP Nicolet Viking Select was chosen to quantitatively assess cognitive functions of the patients. Quality of life was assessed by the use of SF 36. Results and discussion. In the group with MS and CI, compared with patients who have MS but no cognitive disorders, the indicators of general health were lower (52.30±13.90 and 58.22±10.96 points, respectively, p<0.05), physical functioning (69.23±19.79 and 77.13±15.46 points, respectively, p<0.05), emotional role functioning (42.17±21.79 and 56.93±19.84 points, respectively, p<0.05), self-assessment of mental state (53.68±11.84 and 58.39±12.4 points, respectively, p<0.05). In patients with MS and cognitive disorders, a strong association was found between the results of the MMSE test (r=0.39; p=0.015), the Wechsler memory test score (r=0.29; p=0.014), the FAB test score (r=0.43; p=0.018), and physical functioning scores. Mental health scores were associated with the results of the Wexler test (r=0.27; p=0.014). In the group with MS and CI, there was a positive correlation between the amplitude of P300 and indicators of physical functioning (r=0.40; p=0.016). Findings. In the group of patients with MS and CI, compared with patients without cognitive disorders, there is a decrease in the quality of life, especially in indicators of physical functioning. The quality-of-life parameters of patients with MS are associated with cognitive functions determined both by neuropsychological testing and by P300.

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Effects of Occupation-Based Intervention for Older People with Mild Dementia in the Institution

Environment-Behaviour Proceedings Journal ◽

10.21834/ebpj.v6i16.2727 ◽

2021 ◽

Vol 6 (16) ◽

pp. 119-125

Author(s):

Syamsul Anwar Sultan Ibrahim ◽

Akehsan Dahlan ◽

Ahmad Zamir Che Daud

Keyword(s):

Quality Of Life ◽

Older People ◽

Cognitive Functions ◽

Social Relationship ◽

Publishing House ◽

Control Group ◽

Mild Dementia ◽

People With Dementia ◽

Significant Difference

Older people with dementia always experience the cognitive difficulties that are believed to impact their daily life significantly. However, information regarding occupation-based intervention toward older people with mild dementia in the institution is inconclusive. The results of this randomized controlled trial indicate a significant difference in cognitive functions, social relationship, and the quality of life. Participants in the experimental group improved significantly compared to the participants in the control group. Engagement in occupational activities should be encouraged to older people with mild dementia in institution to facilitate the cognitive functions, social relationship, and quality of life. Keywords: older people; mild dementia; occupation-based; quality of life eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v6i16.2727

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Evaluation of cognitive functions and quality of life

Handbook of Clinical Neurology - Neuro-Oncology. Vol 104 HCN Series ◽

10.1016/b978-0-444-52138-5.00014-1 ◽

2012 ◽

pp. 173-183 ◽

Cited By ~ 1

Author(s):

Martin J.B. Taphoorn ◽

Martin Klein

Keyword(s):

Quality Of Life ◽

Cognitive Functions

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Efficacy and impact on cognitive functions and quality of life of perampanel as first add-on therapy in patients with epilepsy: A retrospective study

Epilepsy & Behavior ◽

10.1016/j.yebeh.2019.07.005 ◽

2019 ◽

Vol 98 ◽

pp. 139-144 ◽

Cited By ~ 3

Author(s):

Raffaele Rea ◽

Enea Traini ◽

Rosaria Renna ◽

Francesco Pagliuca ◽

Marianna Pezzella ◽

...

Keyword(s):

Quality Of Life ◽

Retrospective Study ◽

Cognitive Functions ◽

Patients With Epilepsy

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Does pharmacological castration as adjuvant therapy for prostate cancer after radiotherapy affect anxiety and depression levels, cognitive functions and quality of life?

Psycho-Oncology ◽

10.1002/pon.2095 ◽

2011 ◽

Vol 22 (2) ◽

pp. 346-351 ◽

Cited By ~ 23

Author(s):

Paweł J. Wiechno ◽

Małgorzata Sadowska ◽

Tomasz Kalinowski ◽

Wojciech Michalski ◽

Tomasz Demkow

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Adjuvant Therapy ◽

Cognitive Functions ◽

Anxiety And Depression

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The effect of reminiscence therapy on cognitive functions, depression, and quality of life in Alzheimer patients: Randomized controlled trial

International Journal of Geriatric Psychiatry ◽

10.1002/gps.4980 ◽

2018 ◽

Vol 34 (1) ◽

pp. 47-53 ◽

Cited By ~ 12

Author(s):

Neslihan Lök ◽

Kerime Bademli ◽

Alime Selçuk‐Tosun

Keyword(s):

Quality Of Life ◽

Randomized Controlled Trial ◽

Cognitive Functions ◽

Controlled Trial ◽

Reminiscence Therapy ◽

Randomized Controlled

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Physical, cognitive and psychosocial effects of telerehabilitation-based motor imagery training in people with multiple sclerosis: A randomized controlled pilot trial

Journal of Telemedicine and Telecare ◽

10.1177/1357633x18822355 ◽

2019 ◽

Vol 26 (5) ◽

pp. 251-260 ◽

Cited By ~ 2

Author(s):

Turhan Kahraman ◽

Sema Savci ◽

Asiye Tuba Ozdogar ◽

Zumrut Gedik ◽

Egemen Idiman

Keyword(s):

Quality Of Life ◽

Motor Imagery ◽

Cognitive Functions ◽

Walking Speed ◽

Dynamic Balance ◽

Pilot Trial ◽

Control Group ◽

Walking Ability ◽

Balance Confidence

Introduction Motor imagery training delivered at home via telerehabilitation is a novel rehabilitation concept. The aim was to investigate the effects of telerehabilitation-based motor imaging training (Tele-MIT) on gait, balance and cognitive and psychosocial outcomes in people with multiple sclerosis (pwMS). Methods This randomized, controlled pilot trial included pwMS and healthy individuals. pwMS were randomly divided into two groups, intervention and control. The intervention group received Tele-MIT twice a week for 8 weeks. The control group was a wait-list group without any additional specific treatment. Healthy participants served as a baseline comparison. The Dynamic Gait Index, used to assess dynamic balance during walking, was the primary outcome. Secondary outcomes included assessments of walking speed, endurance and perceived ability, balance performance assessed by a computerized posturography device, balance confidence, cognitive functions, fatigue, anxiety, depression and quality of life. Results Baseline comparisons with healthy individuals revealed that motor imagery abilities were preserved in pwMS ( p > 0.05). The intervention group exhibited significant improvements in dynamic balance during walking ( p = 0.002), walking speed ( p = 0.007), perceived walking ability ( p = 0.008), balance confidence ( p = 0.002), most cognitive functions ( p = 0.001–0.008), fatigue ( p = 0.001), anxiety ( p = 0.001), depression ( p = 0.005) and quality of life ( p = 0.002). No significant changes were observed in the control group in any of the outcome measures ( p > 0.05). Discussion Tele-MIT is a novel method that proved feasible and effective in improving dynamic balance during walking, walking speed and perceived walking ability, balance confidence, cognitive functions, fatigue, anxiety, depression and quality of life in pwMS.

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