Patterns of lymphatic spread in rectal cancer. A topographical analysis on lymph node metastases

2002 ◽  
Vol 38 (7) ◽  
pp. 911-918 ◽  
Author(s):  
W.H. Steup ◽  
Y. Moriya ◽  
C.J.H. van de Velde
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Lymphatic Spread ◽  
Node Metastases ◽  
Topographical Analysis

scholarly journals Lateral Pelvic Lymph Node Metastases in Rectal Cancer: A Systematic Review

2019 ◽  
Vol 43 (12) ◽  
pp. 3198-3206 ◽  
Author(s):  
Y. Atef ◽  
T. W. Koedam ◽  
S. E. van Oostendorp ◽  
H. J. Bonjer ◽  
A. R. Wijsmuller ◽  
...  
Keyword(s):  
Systematic Review ◽  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Pelvic Lymph Node ◽  
Lateral Pelvic Lymph Node ◽  
Node Metastases

Postoperative chemoradiotherapy in patients with rectal cancer, prognostic factors for disease control and survival

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 13575-13575 ◽  
Author(s):  
M. Hetnal ◽  
K. Malecki ◽  
S. Korzeniowski ◽  
T. Zemelka
Keyword(s):  
Rectal Cancer ◽  
Prognostic Factors ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Lymph Node Metastases ◽  
Lymph Node Involvement ◽  
Fatty Tissue ◽  
Free Survival ◽  
Node Involvement ◽  
Node Metastases

13575 Background: The aim of this paper is an assessment of results of adjuvant chemoradiotherapy in patients with rectal cancer with respect to prognostic factors, causes of treatment failures and treatment tolerance. Methods: 178 pts with Dukes’ stage B or C rectal cancer received postoperative chemoradiotherapy between 1993 and 2002. Median age was 62; 110 patients were males, 68 were females. Median follow-up time was 45 months. Main endpoints of the analysis were locoregional recurrence-free survival (LRRFS), distant relapse free survival (DRFS), disease free survival (DFS) and overall survival (OS). Kaplan-Meier method was used to calculate survival rates. Univariate and multivariate analyses of prognostic factors were performed using log rank and Cox’s proportional hazard method. Results: The 5-year LRRFS was 73%, DRFS was 80%, DFS was 61% and OS was 65%. Lymph node involvement and method of resection (AR favoured) were the only independent prognostic factors for LRRFS. Lymph node involvement, in particular when four or more are involved, was independent prognostic factors for DFS. For DRFS are histological grade, lymph node involvement and extracapsular extension of the lymph node metastases. For OS, the independent prognostic factors were infiltration of the pararectal fatty tissue, lymph node involvement in particular when four or more are involved, total number of chemotherapy cycles (at least six favoured). The 5-year LRRFS was 73%, DRFS was 80%, DFS was 61% and OS was 65%. Radiation therapy was well tolerated in 45% of patients. Most common early reactions were diarrhoea, nausea/vomiting and leucopoenia. Conclusions: Involvement of lymph nodes and method of resection were the only independent prognostic factors for LRRFS. Prognostic factors for OS were infiltration of the pararectal fatty tissue, lymph node metastases, four or more involved lymph nodes, total number of chemotherapy cycles. No significant financial relationships to disclose.

Predicting lymph node metastases in rectal cancer

1994 ◽  
Vol 37 (1) ◽  
pp. 52-57 ◽  
Author(s):  
T. J. Saclarides ◽  
A. K. Bhattacharyya ◽  
C. Britton-Kuzel ◽  
D. Szeluga ◽  
S. G. Economou
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Node Metastases

scholarly journals Study of Para-aortic Lymph Node Metastases of Left Side Colon and Rectal Cancer.

1996 ◽  
Vol 29 (11) ◽  
pp. 2122-2126 ◽  
Author(s):  
Hidewaki Nakagawa ◽  
Nobuteru Kikkawa ◽  
Toshio Yagyu ◽  
Hideyuki Mishima ◽  
Kazuhiro Fukuda ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Colon And Rectal Cancer ◽  
Aortic Lymph Node ◽  
Node Metastases

Risk factors related to lymph node metastases after neoadjuvant therapy for locally advanced rectal cancer

2009 ◽  
Vol 28 (9) ◽  
pp. 923-927
Author(s):  
Zhi-Fan Zeng ◽  
Pei-Rong Ding ◽  
Zhi-Zhong Pan ◽  
Jun-Zhong Lin ◽  
Li-Ren Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rectal Cancer ◽  
Lymph Node ◽  
Neoadjuvant Therapy ◽  
Lymph Node Metastases ◽  
Locally Advanced ◽  
Advanced Rectal Cancer ◽  
Locally Advanced Rectal Cancer ◽  
Node Metastases

Predicting lymph node metastases in early rectal cancer

2013 ◽  
Vol 49 (5) ◽  
pp. 1104-1108 ◽  
Author(s):  
Deborah Saraste ◽  
Ulf Gunnarsson ◽  
Martin Janson
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Early Rectal Cancer ◽  
Node Metastases

scholarly journals Cost comparisons of endoscopic and surgical resection of stage T1 rectal cancer

2021 ◽  
Vol 09 (10) ◽  
pp. E1512-E1519
Author(s):  
Victoria Arthursson ◽  
Roberto Rosén ◽  
Jenny M. Norlin ◽  
Katarina Gralén ◽  
Ervin Toth ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
High Risk ◽  
Surgical Resection ◽  
Lymph Node Metastases ◽  
T1 Rectal Cancer ◽  
Hypothetical Scenario ◽  
National Cohort ◽  
Node Metastases ◽  
Robotic Resection

Abstract Background and study aims Management of T1 rectal cancer is complex and includes several resection methods, making cost comparisons challenging. The aim of this study was to compare costs of endoscopic and surgical resection and to investigate hypothetical cost scenarios for the treatment of T1 rectal cancer. Patients and methods Retrospective population-based cost minimization study on prospectively collected data on T1 rectal cancer patients treated using endoscopic submucosal dissection (ESD), transanal endoscopic microsurgery (TEM), open, laparoscopic, or robotic resection, in Skåne County, Sweden (2011–2017). The hypothetical cost scenarios were based on the distribution of high-risk features of lymph node metastases in a national cohort (2009–2017). Results Eighty-five patients with T1 RC undergoing ESD (n = 16), TEM (n = 17), open (n = 35), laparoscopic (n = 9), and robotic (n = 8) resection were included. ESD had a total 1-year cost of 5165 € and was significantly (P < 0.05) less expensive compared to TEM (14871€), open (21 453 €), laparoscopic (22 488 €) and robotic resection (26 562 €). Risk factors for lymph node metastases were seen in 68 % of 779 cases of T1 rectal cancers included in the national cohort. The hypothetical scenario of performing ESD on all T1 RC had the lowest total 1-year per patient cost compared to all other alternatives. Conclusions This is the first study analyzing total 1-year costs of endoscopic and surgical methods to resect T1 rectal cancer, which showed that the cost of ESD was significantly lower compared to TEM and surgical resection. In fact, based on hypothetical cost scenarios, ESD is still justifiable from a cost perspective even when all high-risk cases are followed by surgery in accordance to guidelines.

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