A pivotal study in human prostate cancer tissues and cell lines to measure the expression levels of eukaryotic Elongation Factor 1A proteins and the effect of a nucleic acid-based GT75 aptamer

2020 ◽  
Vol 138 ◽  
pp. S49
Author(s):  
B. Scaggiante ◽  
B. Dapas ◽  
A. Bosutti ◽  
F. Giudici ◽  
R. Bussani ◽  
...  
2011 ◽  
Vol 62 (2) ◽  
pp. 84-92 ◽  
Author(s):  
Shinya Sato ◽  
Satoru Takahashi ◽  
Makoto Asamoto ◽  
Makoto Nakanishi ◽  
Toshiaki Wakita ◽  
...  

2006 ◽  
Vol 175 (4S) ◽  
pp. 258-258
Author(s):  
Ruth Schwaninger ◽  
Cyrill A. Rentsch ◽  
Antoinette Wetterwald ◽  
Irena Klima ◽  
Gabri Van der Pluijm ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3268
Author(s):  
Katja S. Håheim ◽  
Emil Lindbäck ◽  
Kah Ni Tan ◽  
Marte Albrigtsen ◽  
Ida T. Urdal Helgeland ◽  
...  

A series of novel quinoline-based tetracyclic ring-systems were synthesized and evaluated in vitro for their antiplasmodial, antiproliferative and antimicrobial activities. The novel hydroiodide salts 10 and 21 showed the most promising antiplasmodial inhibition, with compound 10 displaying higher selectivity than the employed standards. The antiproliferative assay revealed novel pyridophenanthridine 4b to be significantly more active against human prostate cancer (IC50 = 24 nM) than Puromycin (IC50 = 270 nM) and Doxorubicin (IC50 = 830 nM), which are used for clinical treatment. Pyridocarbazoles 9 was also moderately effective against all the employed cancer cell lines and moreover showed excellent biofilm inhibition (9a: MBIC = 100 µM; 9b: MBIC = 100 µM).


2009 ◽  
Vol 46 (2) ◽  
pp. 123-130
Author(s):  
Camila B. Piantino ◽  
Juliana M. Sousa-Canavez ◽  
Marta Bellodi-Privato ◽  
Miguel Srougi ◽  
Luiz Heraldo Camara-Lopes ◽  
...  

1999 ◽  
Vol 58 (7) ◽  
pp. 1097-1107 ◽  
Author(s):  
Jin T.E Lim ◽  
Gary A Piazza ◽  
Edward Kyu-Ho Han ◽  
Thomas M Delohery ◽  
Han Li ◽  
...  

2005 ◽  
Vol 206 (2) ◽  
pp. 214-219 ◽  
Author(s):  
Tine Van de Sande ◽  
Tania Roskams ◽  
Evelyne Lerut ◽  
Steven Joniau ◽  
Hein Van Poppel ◽  
...  

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