Flotation separation of molybdenite and talc using tragacanth gum as depressant and potassium butyl xanthate as collector

Abstract Electrospun polyvinyl alcohol and Tragacanth Gum were used to develop nanofibrous scaffolds containing poorly water-soluble beta-sitosterol. Different Concentration and Ratio of Polymeric composite: (10%) of β-S concentration in (PVA) 8 %, (TG) 0.5%, and 1% respectively were added, prepared and electrospun. The methods have included four parameters (Solution concentration, feeding rate, voltage, and distance of the collector to the tip of the needle) for designing and compared the nanofibers' average diameters. The nanofibers collected were identified via SEM, FTIR, and XRD measurements. A contact angle measurement described the hydrophilicity of the scaffold. MTT test was assessed for obtained nanofibers by using L929 normal fibroblast cells. The %age of mechanical strength, porosity, and deterioration of the scaffolds was well discussed. The average nanofibre ranged from 63 ± 20 nm to 97 ± 46 nm in diameters. The nanofibers loaded with β-S were freely soluble in water and displayed a short release lag time. The dissolution was related to an immediate dissolution, submicron-level recrystallization of β-S with sufficient conditions for nanofibers for L929 cell culture that could be used in biomedical applications. It concluded that electrospinning is a promising technique for poorly water-soluble β-S formulations that could be used in biomedical applications.

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Production and Characterization of Keratin/Tragacanth Gum Nanohydrogels for Drug Delivery in Medical Textiles

Frontiers in Materials ◽

10.3389/fmats.2021.720385 ◽

2021 ◽

Vol 8 ◽

Author(s):

Nazanin Mansouri Shirazi ◽

Niloofar Eslahi ◽

Adeleh Gholipour-Kanani

Keyword(s):

Disulfide Bonds ◽

Antibacterial Properties ◽

Antimicrobial Properties ◽

Spherical Shape ◽

Herbal Extract ◽

Minimum Size ◽

Mechanical Resistance ◽

Tragacanth Gum ◽

Medical Textiles

Keratin protein has been applied for biomedical applications due to its biocompatibility, biodegradability, mechanical resistance, and bioavailability. Tragacanth gum (TG) as a polysaccharide-based biopolymer has wound healing and antimicrobial properties. In this study, keratin was extracted from protein-based chicken feather by using reduction hydrolysis (sodium sulfide), and nanogels of keratin and TG composites at different ratios were produced by using the chemical cross-linking method. Then, cinnamon (5 and 10%) as an antibacterial herbal extract was added to the nanogels and coated on cotton fabric. The morphology and size of the composite nanogels, chemical structure, biological, and antibacterial properties were evaluated. According to DLS results, TGK2:1 (ratio of TG to keratin = 2:1) had the minimum size (80 nm) and PDI (0.1), and therefore, this sample was chosen as the optimum one. FESEM and TEM images showed the semi-spherical shape of the produced nanogels. FTIR spectra revealed the possible hydrogen bonding between the components, and the formation of disulfide bonds after the addition of hydrogen peroxide was confirmed by XPS. After loading cinnamon into the nanogels, an increase in size was observed from 80 nm for free-nanogel to 85 and 105 nm for 5 and 10% extract-loaded nanogels, respectively. Besides, more cinnamon was released from the treated fabrics by increasing time and cinnamon concentration. The antibacterial test exhibited good antibacterial properties against both Gram-positive and Gram-negative bacteria. Finally, MTT assay approved the biocompatibility of the produced nanogels for potential use in medical textiles.

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