Recurrent lower gingival squamous cell carcinoma spreading along the pathway of the inferior alveolar nerve

1995 ◽  
Vol 80 (3) ◽  
pp. 369-375 ◽  
Author(s):  
Minoru Fujita ◽  
Yutaka Hirokawa ◽  
Kumiko Naito ◽  
Nobuharu Tagashira ◽  
Kouji Yajin ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Inferior Alveolar Nerve ◽  
Gingival Squamous Cell Carcinoma

The Length of Peri-Neural Spreading in Clinically Mandibular Invaded Oral Cavity Squamous Cell Carcinoma

2020 ◽  
pp. 459-464
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lymphovascular Invasion ◽  
Perineural Invasion ◽  
Inferior Alveolar Nerve ◽  
Surgical Margin ◽  
Neural Invasion ◽  
Resected Margin

Background: The objective of surgical management of oral squamous cell carcinoma (OSCC) is adequate resection with a clear margin. However, there is still a debate as to the optimal length for a mandibular resected margin. Objective: To examine the length of peri-neural spreading in T4 mandibular invaded oral cavity squamous cell carcinoma. Materials and Methods: Twenty-eight T4 pathological OSCC specimens that involved mandible and serial slices were studied and the length of tumor spreading along the inferior alveolar nerve (IAN) was determined. Tumor characteristics, risk factors, and survival were analyzed. Results: The incidence of peri-neural invasion was 11.11%, and IAN invasion was found in 14.29% of the tumor-invaded mandibular marrow. The length of tumor spreading along IAN was 3 to 12 mm. Poor prognostic factors of T4 OSCC were it being located on the tongue (HR 14.16), was pathological N2-3 (HR 31.05), and had high-risk features such as peri-neural invasion, lymphovascular invasion, and extra-nodal extension. Conclusion: A mandibular resected margin of at least 18 mm is recommended as a clear surgical margin in cases of T4 mandibular invasion OSCC. Keywords: Oral cancer, Perineural invasion, Inferior alveolar nerve, Squamous cell carcinoma, Mandibulectomy

Gingival Squamous Cell Carcinoma Mimicking a Dentoalveolar Abscess: Report of a Case

2007 ◽  
Vol 33 (2) ◽  
pp. 177-180 ◽  
Author(s):  
J LEE ◽  
S CHENG ◽  
S LIN ◽  
C CHIANG ◽  
C YU ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Gingival Squamous Cell Carcinoma

scholarly journals Bone invasion by gingival squamous cell carcinoma. Focus on role of osteoclast-activated cytokines.

2003 ◽  
Vol 49 (3) ◽  
pp. 171-178
Author(s):  
Takahiko SHIBAHARA ◽  
Hiroyasu NOMA ◽  
Takeshi NOMURA ◽  
Ryo TAKAGI ◽  
Keiko YOKOO ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Bone Invasion ◽  
Gingival Squamous Cell Carcinoma

scholarly journals Tetraspanin gene expression levels as potential biomarkers for malignancy of gingival squamous cell carcinoma

2009 ◽  
Vol 124 (12) ◽  
pp. 2911-2916 ◽  
Author(s):  
Chizuru Hirano ◽  
Masaki Nagata ◽  
Arhab A. Noman ◽  
Nobutaka Kitamura ◽  
Makoto Ohnishi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Expression Levels ◽  
Gingival Squamous Cell Carcinoma ◽  
Gene Expression Levels ◽  
Potential Biomarkers
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