Multicenter study of weekly trastuzumab, paclitaxel and carboplatin followed by a week of rest every 28 days in patients with HER2+ metastatic breast cancer – incidence of central nervous system metastases

2008 ◽  
Vol 6 (7) ◽  
pp. 172-173
Author(s):  
J. Salvador ◽  
M. Ruiz-Borrego ◽  
J. Bayo-Calero ◽  
M. Lomas-Garrido ◽  
A. Moreno-Vega ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Metastatic Breast Cancer ◽  
Cancer Incidence ◽  
Multicenter Study ◽  
Breast Cancer Incidence ◽  
Metastatic Breast ◽  
Central Nervous System Metastases

scholarly journals Glycoprotein M6A (GPM6A) is over-expressed in brain metastatic breast cancer.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Metastatic Breast Cancer ◽  
Microarray Data ◽  
Metastatic Breast ◽  
Breast Cancer Patients ◽  
Significant Differential Expression ◽  
Central Nervous System Metastases ◽  
The Brain

One study reported the incidence of central nervous system metastases in breast cancer patients treated with trastuzumab as 34% (1). We mined published microarray data (2, 3) to discover genes associated with brain metastasis in breast cancer. We identified significant differential expression of glycoprotein M6A, encoded by GPM6A (4, 5), in the brain metastases of patients with metastatic breast cancer. GPM6A may be relevant to the biology underlying colonization of the brain with metastatic breast cancer clones.

scholarly journals The L-type lectin LMAN2 is over-expressed in brain metastatic breast cancer.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Metastatic Breast Cancer ◽  
Microarray Data ◽  
Metastatic Breast ◽  
Breast Cancer Patients ◽  
Significant Differential Expression ◽  
Central Nervous System Metastases ◽  
The Brain

One study reported the incidence of central nervous system metastases in breast cancer patients treated with trastuzumab as 34% (1). We mined published microarray data (2, 3) to discover genes associated with brain metastasis in breast cancer. We identified significant differential expression of the L-type lectin LMAN2 (4-7), also known as VIP36, in patients with breast cancer. LMAN2 may be relevant to the biology underlying colonization of the brain with metastatic breast cancer clones.

scholarly journals Ma1 antigen (PNMA1) is over-expressed in brain metastatic breast cancer.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Metastatic Breast Cancer ◽  
Microarray Data ◽  
Metastatic Breast ◽  
Breast Cancer Patients ◽  
Significant Differential Expression ◽  
Central Nervous System Metastases ◽  
The Brain

One study reported the incidence of central nervous system metastases in breast cancer patients treated with trastuzumab as 34% (1). We mined published microarray data (2, 3) to discover genes associated with brain metastasis in breast cancer. We identified significant differential expression of the paraneoplastic Ma1 antigen, encoded by the PNMA1 gene, in the brain metastases of patients with breast cancer. PNMA1 may be relevant to the biology underlying colonization of the brain with metastatic breast cancer clones.

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