Application of the comet assay for monitoring DNA damage in workers exposed to chronic low-dose irradiation

Author(s):  
Marcin Kruszewski ◽  
Maria Wojewódzka ◽  
Teresa Iwanen̄ko ◽  
Andrew R Collins ◽  
Irena Szumiel
Author(s):  
Maria Wojewódzka ◽  
Marcin Kruszewski ◽  
Teresa Iwaneñko ◽  
Andrew R. Collins ◽  
Irena Szumiel

2019 ◽  
Vol 489 (2) ◽  
pp. 199-204
Author(s):  
A. Ya. Bolsunovsky ◽  
D. V. Dementyev ◽  
T. S. Frolova ◽  
E. A. Trofimova ◽  
E. M. Iniatkina ◽  
...  

The effect of -radiation on the level of nuclear DNA damage in onion seedlings (Allium-test) was studied using the comet assay. DNA breaks were first found in cells of onion seedlings exposed to low-dose radiation ( 0,1 Gy). Dose dependence of DNA damage parameters showed nonlinear behavior: a linear section in the low-dose region (below 0,1 Gy) and a dose-independent plateau in the dose range between 1 and 5 Gy. Thus, the comet assay can be used to estimate the biological effects of low-dose gamma-radiation on Allium cepa seedlings.


1998 ◽  
Vol 149 (4) ◽  
pp. 396 ◽  
Author(s):  
Robert S. Malyapa ◽  
Chen Bi ◽  
Eric W. Ahern ◽  
Joseph L. Roti Roti

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