scholarly journals 339 Myocardial strain analysis in an animal model of doxorubicin induced cardiomyopathy

2006 ◽  
Vol 7 ◽  
pp. S42-S42
Author(s):  
G DISALVO ◽  
E PIEGARI ◽  
G PACILEO ◽  
B CASTALDI ◽  
P GOLINO ◽  
...  
Keyword(s):  
Animal Model ◽  
Myocardial Strain ◽  
Strain Analysis ◽  
Myocardial Strain Analysis

scholarly journals Echocardiographic Myocardial Strain Analysis Describes Subclinical Cardiac Dysfunction after Craniospinal Irradiation in Pediatric and Young Adult Patients with Central Nervous System Tumors

2020 ◽  
Author(s):  
Thomas D Ryan ◽  
Hugo R. Martinez ◽  
Ralph Salloum ◽  
Erin Wright ◽  
Lauren Bueche ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Cardiac Dysfunction ◽  
Myocardial Strain ◽  
Strain Analysis ◽  
Late Time ◽  
Systolic Strain ◽  
Peak Systolic Strain ◽  
Myocardial Strain Analysis ◽  
Late Time Point ◽  
Time Point

Abstract Background: Craniospinal irradiation (CSI) is part of the treatment of central nervous system (CNS) tumors and is associated with cardiovascular disease in adults. Global myocardial strain analysis including longitudinal peak systolic strain (GLS), circumferential peak systolic strain (GCS) and radial peak systolic strain (GRS) can reveal subclinical cardiac dysfunction.Methods: Retrospective, single-center study in patients managed with CSI vs. age-matched controls. Clinical data and echocardiography, including myocardial strain analysis, were collected at early (<12 months) and late ( 12 months) after completion of CSI.Results: Echocardiograms were available in 20 early and 34 late patients. Patients at the late time point were older (21.7±10.4 vs. 13.3 9.6 years), and further out from CSI (13.1±8.8 vs. 0.2±0.3 years). Standard echocardiographic parameters were normal for all subjects. For the early time, CSI vs. control: GLS was -16.8 3.6% vs. -21.3 4.0% (p=0.0002), GCS was -22.5 5.2% vs. -21.3 3.4% (p=0.28), and GRS was 21.8 11.0% vs. 26.9 7.7% (p=0.07). At the late time point, CSI vs. control: GLS was -16.2 5.4% vs. -21.6 3.7% (p<0.0001), GCS was -20.9 6.8% vs. -21.9 3.5% (p=0.42), and GRS was 22.5 10.0% vs. 27.3 8.3% (p=0.03). Radiation type (proton vs. photon), and radiation dose (<30 Gy vs. 30 Gy) did not impact any parameter.Conclusions: Subclinical cardiac systolic dysfunction by GLS is present both early and late after CSI. These results argue for inclusion of baseline cardiovascular assessment and early initiation of longitudinal follow-up post CSI.

Myocardial strain analysis of echocardiographic sequences using non-rigid registration

2005 ◽  
Author(s):  
M.J. Ledesma-Carbayo ◽  
A. Santos ◽  
J. Kybic ◽  
P. Mahia-Casado ◽  
M.A. Garcia-Feernandez ◽  
...  
Keyword(s):  
Myocardial Strain ◽  
Strain Analysis ◽  
Rigid Registration ◽  
Myocardial Strain Analysis

Feature-tracking myocardial strain analysis in acute myocarditis: diagnostic value and association with myocardial oedema

2017 ◽  
Vol 27 (11) ◽  
pp. 4661-4671 ◽  
Author(s):  
Julian A. Luetkens ◽  
Ulrike Schlesinger-Irsch ◽  
Daniel L. Kuetting ◽  
Darius Dabir ◽  
Rami Homsi ◽  
...  
Keyword(s):  
Feature Tracking ◽  
Acute Myocarditis ◽  
Myocardial Strain ◽  
Strain Analysis ◽  
Diagnostic Value ◽  
Myocardial Oedema ◽  
Myocardial Strain Analysis
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