W01.81 Urokinase gene therapy enhances angio-and arteriogenesis in the rat model of acute myocardial infarction and beneficially adds to therapeutic angiogenesis in VEGF gene therapy

2004 ◽  
Vol 5 (1) ◽  
pp. 19
Author(s):  
K. Talitskiy ◽  
Z. Tsokolaeva ◽  
D. Traktouev ◽  
K. March ◽  
V. Tkachuk ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Gene Therapy ◽  
Rat Model ◽  
Therapeutic Angiogenesis ◽  
Vegf Gene

HGF or VEGF gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction

2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
T Deuse ◽  
W Zimmermann ◽  
T Eschenhagen ◽  
H Reichenspurner ◽  
RC Robbins ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Stem Cell ◽  
Gene Transfer ◽  
Mesenchymal Stem Cell ◽  
Myocardial Salvage ◽  
Vegf Gene

Acute Myocardial Infarction in the Rat Model: Esmolol-Based Cardioplegia versus Potassium-Based Cardioplegia

2020 ◽  
Author(s):  
A. Veitinger ◽  
A. Komguem ◽  
M. Heep ◽  
B. Niemann ◽  
P. Grieshaber ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Rat Model

scholarly journals VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond

Gene Therapy ◽  
2012 ◽  
Vol 19 (6) ◽  
pp. 622-629 ◽  
Author(s):  
M Giacca ◽  
S Zacchigna
Keyword(s):  
Gene Therapy ◽  
Therapeutic Angiogenesis ◽  
Vegf Gene

Changes in adiponectin expression in acute myocardial infarction rats and the significance of bisoprolol intervention

2011 ◽  
Vol 89 (2) ◽  
pp. 109-115 ◽  
Author(s):  
Song Zhang ◽  
Ben He ◽  
Steven Goldstein ◽  
Junbo Ge ◽  
Zuyue Wang ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Protein Expression ◽  
Reverse Transcriptase ◽  
Rat Model ◽  
Protective Factor ◽  
Sham Operation ◽  
Rt Pcr ◽  
Sham Operation Group ◽  
Operation Group

The aims of this study were to explore the changes in expression of myocardial adiponectin (APN), changes in serum APN, and the significance of bisoprolol intervention in acute myocardial infarction (AMI) rats. An AMI rat model was established for the purposes of this study and was used for analysis of serum APN as determined by ELISA. Changes in expression of myocardial APN mRNA and APN protein in AMI rats were determined via reverse transcriptase (RT)–PCR and immunohistochemistry. Serum APN concentration and APN protein expression of the myocardium decreased significantly in the AMI groups compared with the sham operation group, with the lowest serum APN and APN protein expression on day 7 after AMI. On days 7 and 10 after AMI, the expression of myocardial APN mRNA in the AMI groups decreased significantly compared with the sham operation group. However, the APN mRNA increased on day 10 compared with that on day 7. Notably, there was an increase in levels of serum APN and myocardial APN expression after bisoprolol intervention. The expression of myocardial APN and serum APN decreased in AMI rats. APN may be an important protective factor against AMI. Bisoprolol can also protect against AMI because it increases APN expression.

Chrysin attenuates interstitial fibrosis and improves cardiac function in a rat model of acute myocardial infarction

2018 ◽  
Vol 49 (6) ◽  
pp. 555-565 ◽  
Author(s):  
Mei Yang ◽  
Jun Xiong ◽  
Qiang Zou ◽  
Dan-Dan Wang ◽  
Cong-Xin Huang
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Cardiac Function ◽  
Rat Model ◽  
Interstitial Fibrosis
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