ROLE OF PROMYELOCYTIC LEUKAEMIA ZINC FINGER (PLZF) AND PRE-B-CELL LEUKAEMIA TRANSCRIPTION FACTOR (PBX1) IN ANDROGEN-INDEPENDENT PROSTATE CANCER CELL GROWTH

2006 ◽  
Vol 5 (2) ◽  
pp. 123
Author(s):  
T. Kikugawa ◽  
S. Higashiyama ◽  
N. Tanji ◽  
M. Yokoyama
Keyword(s):  
Prostate Cancer ◽  
Transcription Factor ◽  
Cell Growth ◽  
B Cell ◽  
Zinc Finger ◽  
Prostate Cancer Cell ◽  
Cell Leukaemia ◽  
Cancer Cell Growth ◽  
Androgen Independent

Phosphoproteome analysis demonstrates the potential role of THRAP3 phosphorylation in androgen-independent prostate cancer cell growth

PROTEOMICS ◽  
2016 ◽  
Vol 16 (7) ◽  
pp. 1069-1078 ◽  
Author(s):  
Yoko Ino ◽  
Noriaki Arakawa ◽  
Hitoshi Ishiguro ◽  
Hiroji Uemura ◽  
Yoshinobu Kubota ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Growth ◽  
Cancer Cell ◽  
Potential Role ◽  
Prostate Cancer Cell ◽  
Cancer Cell Growth ◽  
Androgen Independent

scholarly journals Evidence that androgen-independent stromal growth factor signals promote androgen-insensitive prostate cancer cell growth in vivo

2009 ◽  
Vol 16 (2) ◽  
pp. 415-428 ◽  
Author(s):  
Kenichiro Ishii ◽  
Tetsuya Imamura ◽  
Kazuhiro Iguchi ◽  
Shigeki Arase ◽  
Yuko Yoshio ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Growth Factor ◽  
Cell Growth ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Receptor Expression ◽  
Urogenital Sinus ◽  
Cancer Cell Growth ◽  
Androgen Ablation ◽  
Androgen Independent

Activation of tumor–stromal interactions is considered to play a critical role in the promotion of tumorigenesis. To discover new therapeutic targets for hormone-refractory prostate tumor growth under androgen ablation therapy, androgen-sensitive LNCaP cells and the derived sublines, E9 (androgen-low-sensitive), and AIDL (androgen-insensitive), were recombined with androgen-dependent embryonic rat urogenital sinus mesenchyme (UGM). Tumors of E9+UGM and AIDL+UGM were approximately three times as large as those of LNCaP+UGM. Tumors grown in castrated hosts exhibited reduced growth as compared with those in intact hosts. However, in castrated hosts, E9+UGM and AIDL+UGM tumors were still approximately twice as large as those of LNCaP+UGM. Cell proliferation in tumors of E9+UGM and AIDL+UGM grown in castrated host, was significantly higher than that in tumors of LNCaP+UGM. In vitro, expression of fibroblast growth factor (FGF)-2 and IGF-I, but not FGF-7 mRNA, was significantly reduced in UGM under androgen starvation. In cell culture, E9 cells were responsive to FGF-2 and FGF-7 stimulation, while AIDL responded to FGF-7 and IGF-1. Expression of FGFR1 and FGFR2 was considerably higher in E9 than those in LNCaP, similarly expression of FGFR2 and IGF-IR were elevated in AIDL. These data suggest that activation of prostate cancer cell growth through growth factor receptor expression may result in the activity of otherwise androgen-independent stromal growth factor signals such as FGF-7 under conditions of androgen ablation.

Role of Testosterone, Estradiol, and Insulin in Diet- and Exercise-Induced Reductions in Serum-Stimulated Prostate Cancer Cell Growth In Vitro

2002 ◽  
Vol 42 (1) ◽  
pp. 112-116 ◽  
Author(s):  
Christopher N. Tymchuk ◽  
R. James Barnard ◽  
Tung H. Ngo ◽  
William J. Aronson
Keyword(s):  
Prostate Cancer ◽  
Cell Growth ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Cancer Cell Growth ◽  
Diet And Exercise ◽  
Exercise Induced

Inhibition of prostate cancer cell growth by an avocado extract: role of lipid-soluble bioactive substances

2005 ◽  
Vol 16 (1) ◽  
pp. 23-30 ◽  
Author(s):  
Qing-Yi Lu ◽  
James R. Arteaga ◽  
Qifeng Zhang ◽  
Sergio Huerta ◽  
Vay Liang W. Go ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Growth ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Cancer Cell Growth ◽  
Bioactive Substances

scholarly journals 1α,25-Dihydroxyvitamin D3 Inhibits Prostate Cancer Cell Growth by Androgen-Dependent and Androgen-Independent Mechanisms*

Endocrinology ◽  
2000 ◽  
Vol 141 (7) ◽  
pp. 2548-2556 ◽  
Author(s):  
Xiao-Yan Zhao ◽  
Donna M. Peehl ◽  
Nora M. Navone ◽  
David Feldman
Keyword(s):  
Prostate Cancer ◽  
Cell Growth ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Cancer Cell Growth ◽  
Dihydroxyvitamin D3 ◽  
Androgen Independent

scholarly journals Protocadherin-PC promotes androgen-independent prostate cancer cell growth

The Prostate ◽  
2006 ◽  
Vol 66 (10) ◽  
pp. 1100-1113 ◽  
Author(s):  
Stephane Terry ◽  
Luis Queires ◽  
Sixtina Gil-Diez-de-Medina ◽  
Min-Wei Chen ◽  
Alexandre de la Taille ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Growth ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Cancer Cell Growth ◽  
Androgen Independent

Role of endoplasmic reticulum calcium content in prostate cancer cell growth regulation by IGF and TNFalpha

2004 ◽  
Vol 201 (2) ◽  
pp. 201-213 ◽  
Author(s):  
Sandrine Humez ◽  
Gillaume Legrand ◽  
Fabien Vanden-Abeele ◽  
Micha�l Monet ◽  
Philipe Marchetti ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Endoplasmic Reticulum ◽  
Cell Growth ◽  
Cancer Cell ◽  
Growth Regulation ◽  
Prostate Cancer Cell ◽  
Calcium Content ◽  
Cancer Cell Growth ◽  
Endoplasmic Reticulum Calcium
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