P.03.7 EUS-GUIDED FINE NEEDLE ASPIRATION OF SOLID PANCREATIC TUMORS IN YOUNG PATIENTS: EXPERIENCE IN A TERTIARY REFERRAL CENTER

2016 ◽  
Vol 48 ◽  
pp. e141-e142
Author(s):  
M.C. Petrone ◽  
E. Dabizzi ◽  
S.G.G. Testoni ◽  
A. Mariani ◽  
P.G. Arcidiacono
2009 ◽  
Vol 69 (5) ◽  
pp. AB335
Author(s):  
Uzma D. Siddiqui ◽  
Manmeet S. Padda ◽  
Federico Rossi ◽  
Lawrence S. Rosenthal ◽  
Visvanathan Murali-Dharan ◽  
...  

Author(s):  
Alexandra M. Gibson ◽  
Michael F. Rosser ◽  
Cintia R. de Oliveira ◽  
Rachel Lampe ◽  
Janice M. Pfeiff ◽  
...  

Abstract CASE DESCRIPTION A 3-year-old 31.1-kg castrated male mixed-breed dog was evaluated because of a 1- to 2-week history of paraparesis, knuckling of the hind feet, and difficulty posturing to urinate or defecate. CLINICAL FINDINGS The dog was paraparetic but weakly ambulatory with a kyphotic posture, a mildly decreased patellar reflex in the right pelvic limb, increased tone in both pelvic limbs, and marked hyperesthesia on paraspinal palpation of the lumbar region. The urinary bladder was enlarged and firm on palpation. Neuroanatomic findings were primarily consistent with localization to the T3-L3 spinal cord segments. Magenetic resonance imaging of the thoracolumbar spinal column revealed a discrete intramedullary spinal cord mass from the cranial aspect of L4 to the middle of L5. The mass was sampled by fine-needle aspiration, and on cytologic evaluation, the suspected diagnosis was an ependymoma. TREATMENT AND OUTCOME Owing to poor prognosis and limited treatment options, the owner elected euthanasia. Postmortem examination of the spinal cord and histologic findings for samples of the mass supported a likely diagnosis of ependymoma. CLINICAL RELEVANCE Ependymoma is a rare neoplasm in dogs but should be considered in young patients with evidence of a tumor in the CNS. Fine-needle aspiration of the spinal cord mass was possible in the dog of this report, and the cytologic findings provided useful diagnostic information.


2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Kiyohito Kato ◽  
Hideki Kamada ◽  
Takayuki Fujimori ◽  
Yuuichi Aritomo ◽  
Masahiro Ono ◽  
...  

We review the utility of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA), a rapid, safe, cost-effective, and accurate diagnostic modality for evaluating pancreatic tumors. EUS-FNA is currently used for the diagnosis and staging of pancreatic tumors. The sensitivity of EUS-FNA for pancreatic malignancy ranges from 75% to 94%, and its specificity approaches 100% in most studies. However, EUS-FNA has some limitations in the diagnosis of well-differentiated or early-stage cancers. Recent evidence suggests that molecular biological analysis using specimens obtained by EUS-FNA improves diagnostic sensitivity and specificity, especially in borderline cytological cases. It was also reported that additional information regarding patient response to chemotherapy, surgical resectability, time to metastasis, and overall survival was acquired from the genetic analysis of specimens obtained by EUS-FNA. Other studies have revealed that the analysis of KRAS, MUC, p53, p16, S100P, SMAD4, and microRNAs is helpful in making the diagnosis of pancreatic carcinoma. In this paper, we describe the present state of genetic diagnostic techniques for use with EUS-FNA samples in pancreatic diseases. We also discuss the role of molecular biological analyses for the diagnosis of pancreatic carcinoma.


Sign in / Sign up

Export Citation Format

Share Document