Lack of association between interleukin-1 receptor antagonist protein gene polymorphism and bone mineral density in Hungarian postmenopausal women

Bone ◽  
2000 ◽  
Vol 27 (4) ◽  
pp. 559-562 ◽  
Author(s):  
É Bajnok ◽  
I Takács ◽  
P Vargha ◽  
G Speer ◽  
Z Nagy ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Gene Polymorphism ◽  
Receptor Antagonist ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Protein Gene ◽  
Interleukin 1 ◽  
Mineral Density ◽  
Interleukin 1 Receptor Antagonist

scholarly journals Estrogen Receptor (ER) Gene Polymorphism May Predict the Bone Mineral Density Response to Raloxifene in Postmenopausal Women on Chronic Hemodialysis

Renal Failure ◽  
2005 ◽  
Vol 27 (2) ◽  
pp. 155-161 ◽  
Author(s):  
Ita Pfeferman Heilberg ◽  
Eddy Hernandez ◽  
Evelyn Alonzo ◽  
Raquel Valera ◽  
Larissa Gorayb Ferreira ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Estrogen Receptor ◽  
Gene Polymorphism ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Chronic Hemodialysis ◽  
Mineral Density ◽  
Density Response

scholarly journals GIPR rs10423928 and bone-mineral density in postmenopausal women in Shanghai

2022 ◽  
Author(s):  
Lizhi Zhang ◽  
Jinwei He ◽  
Xiang Sun ◽  
Dongyue Pang ◽  
Jingjing Hu ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Femoral Neck ◽  
Gene Polymorphism ◽  
Bone Metabolism ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Mineral Density ◽  
Bone Protection

Our previous studies have demonstrated that there is a correlation between GLP-1R SNP and the BMD in postmenopausal women. GLP-1 and GIP are both incretins. Whether the mutation of GIPR gene affects bone metabolism. SNP rs10423928 is a GIPR gene polymorphism that has been studied more frequently. The aim of this study was to investigate the association between GIPR SNP rs10423928 and bone-mineral density (BMD) in postmenopausal women in Shanghai. The GIPR SNP rs10423928 was detected in 884 postmenopausal women in Shanghai, the correlation between the GIPR SNP and BMD was further assessed. The dominant T/T genotype of the GIPR SNP rs10423928 was significantly related to BMD of the femoral neck (P = 0.035) and Ward’s triangle area (P = 0.033). Our research found that the dominant T/T genotype of GIPR SNP rs10423928 in postmenopausal women is significantly associated with higher BMD. The T/T genotype seems to have bone protection.

Sign in / Sign up

Export Citation Format

Share Document