Yield and safety of bedside open lung biopsy in mechanically ventilated patients with acute lung injury or acute respiratory distress syndrome

2009 ◽  
Vol 2009 ◽  
pp. 310-312
Author(s):  
J.A. Barker
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Acute Lung Injury ◽  
Lung Injury ◽  
Lung Biopsy ◽  
Distress Syndrome ◽  
Open Lung Biopsy ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
Open Lung ◽  
Ventilated Patients

scholarly journals What Tidal Volumes Should Be Used in Patients without Acute Lung Injury?

2007 ◽  
Vol 106 (6) ◽  
pp. 1226-1231 ◽  
Author(s):  
Marcus J. Schultz ◽  
Jack J. Haitsma ◽  
Arthur S. Slutsky ◽  
Ognjen Gajic ◽  
David C. Warltier
Keyword(s):  
Mechanical Ventilation ◽  
Acute Lung Injury ◽  
Lung Injury ◽  
Distress Syndrome ◽  
Management Strategies ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
The Past ◽  
Ventilator Management ◽  
Ventilated Patients

Mechanical ventilation practice has changed over the past few decades, with tidal volumes (VT) decreasing significantly, especially in patients with acute lung injury (ALI). Patients without acute lung injury are still ventilated with large--and perhaps too large--VT. Studies of ventilator-associated lung injury in subjects without ALI demonstrate inconsistent results. Retrospective clinical studies, however, suggest that the use of large VT favors the development of lung injury in these patients. Side effects associated with the use of lower VT in patients with ALI seem to be minimal. Assuming that this will be the case in patients without ALI/acute respiratory distress syndrome too, the authors suggest that the use of lower VT should be considered in all mechanically ventilated patients whether they have ALI or not. Prospective studies should be performed to evaluate optimal ventilator management strategies for patients without ALI.

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