scholarly journals P006: Characterizing patients with newly-diagnosed diabetes mellitus in the emergency department: A one-year health records review

CJEM ◽  
2017 ◽  
Vol 19 (S1) ◽  
pp. S79
Author(s):  
H. Ali Khan ◽  
K. Gushulak ◽  
M. Columbus ◽  
I.G. Stiell ◽  
J.W. Yan

Introduction: Diabetes mellitus is an increasingly prevalent chronic condition that is usually managed in an outpatient setting. However, the emergency department (ED) plays a crucial role in the management of diabetic patients, particularly for those who are presenting with newly diagnosed diabetes. Little research has been done to characterize the population of patients presenting to the ED with hyperglycemia with no previous diagnosis of diabetes. The objective of this study was to describe the epidemiology, treatment, and outcomes of patients who were newly diagnosed with diabetes in the ED and to compare those with newly diagnosed type I versus type II diabetes. Methods: A one-year health records review of newly diagnosed diabetes patients ≥18 years presenting to one of four tertiary care EDs was conducted. All patients with a discharge diagnosis of hyperglycemia, diabetic ketoacidosis or hyperosmolar hyperglycemic syndrome were screened, but only those who did not have a previous history of diabetes were included. Trained research personnel collected data on patient characteristics, management, disposition, and outcome. Descriptive statistics were used to summarize the data where appropriate. Results: Of 645 patients presenting with hyperglycemia in the study period, 112 (17.4%) were newly diagnosed diabetes patients. Of these patients, 30 (26.8%) were later diagnosed with type I diabetes and 82 (73.2%) were diagnosed with type II diabetes. For the newly diagnosed type I patients the mean (SD) age was 27.6 (9.9) and the mean (SD) age for type II patients was 52.4 (14.1). Of all the new onset patients, 26.8% were diagnosed with diabetic ketoacidosis. The percentage of patients diagnosed with diabetic ketoacidosis was higher in type I than type II (63.3% vs 13.4%; P<0.01). A total of 49 (43.8%) patients were admitted to the hospital, and more patients with type I were admitted compared to those with type II (66.7% vs 35.4 %; P<0.01). Conclusion: Limited research has been done to describe patients newly diagnosed with diabetes in the ED. Patients with type I were found to be more likely to present to the ED with serious symptoms requiring admission to hospital. Our findings demonstrate that the ED may have a strong potential role for improving diabetic care, by providing future opportunities for education and follow-up in the ED to reduce complications, particularly in type I.

Author(s):  
Jere Häyrynen ◽  
Maija Kärkkäinen ◽  
Aulikki Kononoff ◽  
Leena Arstila ◽  
Pia Elfving ◽  
...  

AbstractThe aim of the study was to describe automated immunoassays for autoantibodies to homocitrulline or citrulline containing telopeptides of type I and II collagen in various disease categories in an early arthritis series.Serum samples were collected from 142 patients over 16 years of age with newly diagnosed inflammatory joint disease. All samples were analyzed with an automated inhibition chemiluminescence immunoassay (CLIA) using four different peptide pairs, each consisting of a biotinylated antigen and an inhibiting peptide. Assays were performed with an IDS-iSYS analyzer. Autoantibodies binding to homocitrulline and citrulline containing C-telopeptides of type I (HTELO-I, TELO-I) and type II collagens (HTELO-II, TELO-II) were analyzed.The mean ratio of HTELO-I inhibition in seropositive and seronegative rheumatoid arthritis (RA) was 3.07 (95% CI 1.41–11.60), p=0.003, and in seropositive and seronegative undifferentiated arthritis (UA) 4.90 (1.85–14.49), p<0.001. The respective mean ratios in seropositive and seronegative RA and UA were in TELO-I 8.72 (3.68–58.01), p<0.001 and 3.13 (1.49–6.16), p=0.008, in HTELO-II 7.57 (3.18–56.60), p<0.001 and 2.97 (1.23–6.69), p=0.037, and in TELO-II 3.01 (1.30–9.51), p=0.002 and 3.64 (1.86–7.65), p=0.008. In reactive arthritis, ankylosing spondylitis, psoriatic arthritis and unspecified spondyloarthritis the inhibition levels were similar to those observed in seronegative RA or UA.Autoantibodies binding to homocitrulline or citrulline containing telopeptides of type I and II collagen did not differ significantly. They were highest among patients with seropositive disease and they differentiated seropositive and seronegative arthritis.


2010 ◽  
Vol 46 (4) ◽  
pp. 562-566 ◽  
Author(s):  
E Snarski ◽  
A Milczarczyk ◽  
T Torosian ◽  
M Paluszewska ◽  
E Urbanowska ◽  
...  

Author(s):  
Kubra Turan ◽  
Esra Copuroglu ◽  
Tam Ali Abbas ◽  
Caglar Keskin ◽  
Didem Ozdemir ◽  
...  

2021 ◽  
Author(s):  
Kubra Turan ◽  
Esra Copuroglu ◽  
Tam Ali Abbas ◽  
Caglar Keskin ◽  
Didem Ozdemir ◽  
...  

2021 ◽  
Vol 28 (11) ◽  
pp. 1546-1551
Author(s):  
Muhammad Umar Khan ◽  
Akhtar Ali Baloch ◽  
Muhammad Arsalan ◽  
Syed Muhammad Adnan

Objectives: To determine the prevalence of metabolic syndrome in patients with newly diagnosed type 2. Study Design: Descriptive Cross Sectional study. Setting: Dow University Hospital. Period: October 2018 to January 2019. Material & Methods: A total 342 patients prevalence of metabolic syndrome in patients with newly diagnosed type II diabetes at Dow University Hospital, Karachi, Pakistan. Data was collected through a questionnaire which is designed to record the age, gender, BMI, FBS, Waist circumference, blood pressure, HDL and triglyceride level of newly diagnosed of diabetic patients. Frequency and percentages were calculated for these variables. SPSS version 21 was used to analyze the overall results. Results: A total of 342 new diagnosed diabetic were included in this study. 189 (55.26%) were males and 153 (44.74%) were females. The mean + SD of age was 48.21±9.28 years. The mean + SD of FBS was about 192±43 mg/dl with ranges from 98 to 482 mg/dl. The mean + SD of Serum TG was about 243±152 mg/dl with ranges from 189 to 325 mg/dl. The mean + SD HDL was about 38.9±9.23 mg/dl with ranges from 12 to 102 mg/dl. The mean + SD of waist circumference was about 110.5±11.90 cm. The mean + SD systolic & diastolic blood pressure was about 150 + 8.23 & 98 + 11.28 respectively. The mean + SD of BMI was 29.23+ 11.23. Metabolic syndrome was diagnosed in 252 (73.68%) in newly diabetic patients. Conclusion: Metabolic syndromes were highly associated with newly diagnosed type II diabetes patients.


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