scholarly journals Rates and predictors of anti-depressant prescribing in Northern Ireland 2011–2015: a data linkage study using the Administrative Data Research Centre (NI)

2019 ◽  
Vol 37 (1) ◽  
pp. 32-38 ◽  
Author(s):  
Mark Shevlin ◽  
Michael Rosato ◽  
Stephanie Boyle ◽  
Daniel Boduszek ◽  
Jamie Murphy

Objectives:Research indicates that anti-depressant prescribing is higher in Northern Ireland (NI) than in the rest of the UK, and that socio-economic and area-level factors may contribute to this. The current study provides comprehensive population-based estimates of the prevalence of anti-depressant prescription prescribing in NI from 2011 to 2015, and examined the associations between socio-demographic, socio-economic, self-reported health and area-level factors and anti-depressant prescription.Methods:Data were derived from the 2011 NI Census (N = 1 588 355) and the Enhanced Prescribing Database. Data linkage techniques were utilised through the Administrative Data Research Centre in NI. Prevalence rates were calculated and binary logistic analysis assessed the associations between contextual factors and anti-depressant prescription.Results:From 2011 to 2015, the percentages of the population in NI aged 16 or more receiving anti-depressant prescriptions were 12.3%, 12.9%, 13.4%, 13.9% and 14.3%, respectively, and over the 5-year period was 24.3%. The strongest predictors of anti-depressant prescription in the multivariate model specified were ‘very bad’ (OR = 4.02) or ‘Bad’ general health (OR = 3.98), and self-reported mental health problems (OR = 3.57). Other significant predictors included social renting (OR = 1.67) and unemployment (OR = 1.25). Protective factors included Catholic religious beliefs, other faith/philosophic beliefs and no faith/philosophic beliefs in comparison to reporting Protestant/other Christian religious beliefs (ORs = 0.78–0.91).Conclusion:The prevalence of anti-depressant prescription in NI appears to be higher than the prevalence of depressive disorders, although this may not necessarily be attributable to over-prescribing as anti-depressants are also prescribed for conditions other than depression. Anti-depressant prescription was linked to several factors that represent socio-economic disadvantage.


2018 ◽  
Author(s):  
Francisco Schneuer ◽  
Elizabeth Milne ◽  
Sarra E. Jamieson ◽  
Gavin Pereira ◽  
Michele Hansen ◽  
...  


2021 ◽  
Author(s):  
Tamas Szakmany ◽  
Joe Hollinghurst ◽  
Richard Pugh ◽  
Ashley Akbari ◽  
Rowena Griffiths ◽  
...  

Abstract Background: The ideal method of identifying frailty is uncertain, and data on long-term outcomes is relatively limited. We examined frailty indices derived from population-scale linked data on Intensive Care Unit (ICU) and hospitalised non-ICU patients with pneumonia to elucidate the influence of frailty on mortality.Methods: Longitudinal cohort study between 2010-2018 using population-scale anonymised data linkage of healthcare records for adults admitted to hospital with pneumonia in Wales. Primary outcome was in-patient mortality. Age, hospital frailty risk score (HFRS), electronic frailty index (eFI), Charlson comorbidity index (CCI), and social deprivation index were entered in the multivariate regression models.Results: Of the 107,188 patients, mean (SD) age was 72.6 (16.6) years, 50% were men. The two frailty indices and the comorbidity index had an increased risk of mortality for individuals with an ICU admission. Advancing age, increased frailty and comorbidity affected short- and long-term mortality. For predicting inpatient deaths, the CCI and HFRS based models were similar, however for longer term outcomes the CCI based model was superior. Discussion: Frailty and comorbidity are significant risk factors for patients admitted to hospital with pneumonia. Frailty and comorbidity scores based on administrative data have only moderate ability to predict outcome.



PLoS ONE ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. e0238182
Author(s):  
Dasamal Tharanga Fernando ◽  
Janneke Berecki-Gisolf ◽  
Stuart Newstead ◽  
Zahid Ansari


BMJ Open ◽  
2017 ◽  
Vol 7 (1) ◽  
pp. e013492 ◽  
Author(s):  
Natalie A Strobel ◽  
Sue Peter ◽  
Kimberley E McAuley ◽  
Daniel R McAullay ◽  
Rhonda Marriott ◽  
...  


BMJ Open ◽  
2012 ◽  
Vol 2 (6) ◽  
pp. e002344 ◽  
Author(s):  
Louisa R Jorm ◽  
Alastair H Leyland ◽  
Fiona M Blyth ◽  
Robert F Elliott ◽  
Kirsty M A Douglas ◽  
...  


Author(s):  
Georgina M Chambers ◽  
Christos A Venetis ◽  
Louisa R Jorm ◽  
Claire M Vajdic

Parity is a potential confounder of the association between medically assisted reproduction (MAR) and health outcomes. This concept paper describes a population-based record linkage study design for selecting MAR-unexposed women matched to the parity of MAR-exposed women, at the time of the first exposure to MAR. Women exposed to MAR were identified from claims for government subsidies for relevant procedures and prescription medicines, linked to perinatal records. Women unexposed to MAR were identified from linked perinatal and death records, matched to exposed women by age, rurality, age of first child (if any) and parity at the date of first MAR. The availability of a longitudinal, whole-of-population dataset (“population spine”) based on enrolments in Australia’s universal health insurance scheme was a critical design element. The example application examines cancer risk in women after exposure to MAR. Parity is a confounder in this setting because it is associated with MAR and hormone-sensitive cancers.



Health Policy ◽  
2008 ◽  
Vol 85 (3) ◽  
pp. 380-390 ◽  
Author(s):  
Rachael Elizabeth Moorin ◽  
Cashel D’Arcy James Holman




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