A new stochastic model of microsatellite evolution
1999 ◽
Vol 36
(03)
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pp. 621-631
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Keyword(s):
Best Fit
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We introduce a continuous-time Markov chain model for the evolution of microsatellites, simple sequence repeats in DNA. We prove the existence of a unique stationary distribution for our model, and fit the model to data from approximately 106 base pairs of DNA from fruit flies, mice, and humans. The slippage rates from the best fit for our model are consistent with experimental findings.
1999 ◽
Vol 36
(3)
◽
pp. 621-631
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2012 ◽
Vol 8
(3/4)
◽
pp. 195
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2009 ◽
Vol 16
(11)
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pp. 1143-1148
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Keyword(s):
Keyword(s):
2018 ◽
Vol 46
(9)
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pp. 1671-1688
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Keyword(s):
Keyword(s):
2019 ◽
Vol 61
(3)
◽
pp. 143
Keyword(s):
2021 ◽