scholarly journals Speciation, serotyping, antimicrobial sensitivity and plasmid content of Proteeae from the environment of calf-rearing units in South West England

1986 ◽  
Vol 97 (3) ◽  
pp. 405-417 ◽  
Author(s):  
P. M. Hawkey ◽  
J. L. Penner ◽  
A. H. Linton ◽  
C. A. Hawkey ◽  
L. J. Crisp ◽  
...  

SUMMARYA survey was undertaken of the occurrence, serotype, antimicrobial sensitivity and plasmid content of members of the tribe Proteeae in the environment of two calf-rearing units in the county of Avon in South West England. Examples of the following species were found:Proteus mirabilis, Prot. vulgaris, Prot. vulgarisBiogroup 2,Morganella morganii, Providencia stuartii, Prov. alcalifaciensandProv. rettgeri. A wide range of sero types was found, many having been previously reported from nosocomial isolates. A total of 15% of isolates carried plasmids; six pairs of isolates were identified which had identical sero typesbut different patterns of plasmid carriage. The antimicrobial sensitivity of the isolates was generally similar to isolates of Proteeae from humans. Although no truly aminoglycosideresistantisolates were found, some isolates ofProv. stuartiiandProv. rettgerihad MIC's higher than the other isolates to gentamicin and netilmicin, suggesting the presence of lowlevels of the enzyme AAC 2′. The study demonstrates that there is a considerable diversityof species and types of Proteeae associated with calves and their environment. It seems likely that a potential cause of colonization of the human gut by Proteeae is the consumption of meat.

1982 ◽  
Vol 46 (339) ◽  
pp. 211-215 ◽  
Author(s):  
P. K. Swart ◽  
F. Moore

AbstractThe U content of cassiterite (SnO2), wolframite (Fe,Mn)WO4, and various sulphides from two localities in the Cornubian batholiths of south-west England has been investigated. Cassiterites showed concentrations of U between 0 and 6 ppm with the higher concentrations corresponding to the darker colour bands. Sulphides contained no detectable U using the fissiontrack method, but high concentrations relate to micro-veining. This veining was also evident in associated wolframite and appeared to have a composition similar to an iron-arsenate mineral associated with the alteration of arsenopyrite. Wolframite exhibited a wide range of U concentrations with sharp zonation and several generations of ore deposition within one crystal. The U was not, however, associated with either the iron- or manganese-rich phases.


Until 2019, TBE was considered only to be an imported disease to the United Kingdom. In that year, evidence became available that the TBEV is likely circulating in the country1,2 and a first “probable case” of TBE originating in the UK was reported.3 In addition to TBEV, louping ill virus (LIV), a member of the TBEV-serocomplex, is also endemic in parts of the UK. Reports of clinical disease caused by LIV in livestock are mainly from Scotland, parts of North and South West England and Wales.4


Microbiome ◽  
2021 ◽  
Vol 9 (1) ◽  
Author(s):  
David Pellow ◽  
Alvah Zorea ◽  
Maraike Probst ◽  
Ori Furman ◽  
Arik Segal ◽  
...  

Abstract Background Metagenomic sequencing has led to the identification and assembly of many new bacterial genome sequences. These bacteria often contain plasmids: usually small, circular double-stranded DNA molecules that may transfer across bacterial species and confer antibiotic resistance. These plasmids are generally less studied and understood than their bacterial hosts. Part of the reason for this is insufficient computational tools enabling the analysis of plasmids in metagenomic samples. Results We developed SCAPP (Sequence Contents-Aware Plasmid Peeler)—an algorithm and tool to assemble plasmid sequences from metagenomic sequencing. SCAPP builds on some key ideas from the Recycler algorithm while improving plasmid assemblies by integrating biological knowledge about plasmids. We compared the performance of SCAPP to Recycler and metaplasmidSPAdes on simulated metagenomes, real human gut microbiome samples, and a human gut plasmidome dataset that we generated. We also created plasmidome and metagenome data from the same cow rumen sample and used the parallel sequencing data to create a novel assessment procedure. Overall, SCAPP outperformed Recycler and metaplasmidSPAdes across this wide range of datasets. Conclusions SCAPP is an easy to use Python package that enables the assembly of full plasmid sequences from metagenomic samples. It outperformed existing metagenomic plasmid assemblers in most cases and assembled novel and clinically relevant plasmids in samples we generated such as a human gut plasmidome. SCAPP is open-source software available from: https://github.com/Shamir-Lab/SCAPP.


2004 ◽  
Vol 48 (1) ◽  
pp. 49-68 ◽  
Author(s):  
Ian Mortimer

The licensing of provincial surgeons and physicians in the post-Restoration period has proved an awkward subject for medical historians. It has divided writers between those who regard the possession of a local licence as a mark of professionalism or proficiency, those who see the existence of diocesan licences as a mark of an essentially unregulated and decentralized trade, and those who discount the distinction of licensing in assessing medical expertise availability in a given region. Such a diversity of interpretations has meant that the very descriptors by which practitioners were known to their contemporaries (and are referred to by historians) have become fragmented and difficult to use without a specific context. As David Harley has pointed out in his study of licensed physicians in the north-west of England, “historians often define eighteenth-century physicians as men with medical degrees, thus ignoring … the many licensed physicians throughout the country”. One could similarly draw attention to the inadequacy of the word “surgeon” to cover licensed and unlicensed practitioners, barber-surgeons, Company members in towns, self-taught practitioners using surgical manuals, and procedural specialists whose work came under the umbrella of surgery, such as bonesetters, midwives and phlebotomists. Although such fragmentation of meaning reflects a diversity of practices carried on under the same occupational descriptors in early modern England, the result is an imprecise historical literature in which the importance of licensing, and especially local licensing, is either ignored as a delimiter or viewed as an inaccurate gauge of medical proficiency.


Geology Today ◽  
2021 ◽  
Vol 37 (5) ◽  
pp. 176-183
Author(s):  
Robert A. Coram ◽  
Jonathan D. Radley ◽  
Michael J. Benton

1997 ◽  
Vol 54 (11) ◽  
pp. 840-840 ◽  
Author(s):  
P Kavanagh ◽  
M E Farago ◽  
I Thornton ◽  
P Elliott ◽  
W Goessler ◽  
...  

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