Laryngeal squamous cell carcinoma presenting as a prelaryngeal, air-filled structure (pseudolaryngocoele)

2007 ◽  
Vol 122 (5) ◽  
pp. 535-537 ◽  
Author(s):  
T S Korampalli ◽  
A Belloso ◽  
P S Hans ◽  
K Irion ◽  
I J Sheppard
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Examination ◽  
Anterior Commissure ◽  
Thyroid Cartilage ◽  
Needle Aspiration ◽  
Neck Mass ◽  
Computed Tomography Scanning

AbstractObjective:We report a unique case of a squamous cell carcinoma of the larynx presenting as a large pseudolaryngocoele, arising through a thyroid cartilage defect.Method:Case report and review of the literature.Case report:A 47-year-old man presented with a two-month history of hoarseness and a large, midline neck swelling. Endoscopic examination revealed a transglottic carcinoma involving the anterior commissure. Fine needle aspiration of the neck mass showed it to be an air-filled structure which transiently collapsed but refilled within minutes. Subsequent computed tomography scanning and histopathological examination revealed that the air-filled mass was created by a defect in the thyroid cartilage, with formation of a pseudolaryngocoele.Conclusions:The anatomy of the anterior commissure region and its effect on the spread of laryngeal carcinoma is reviewed in order to explain the pathophysiology of this unusual presentation. We highlight the need for a high index of suspicion of malignancy if a laryngocoele or pseudolaryngocoele is detected clinically.

Thyroid cartilage invasion in early-stage squamous cell carcinoma involving the anterior commissure

Head & Neck ◽  
2011 ◽  
Vol 34 (10) ◽  
pp. 1476-1479 ◽  
Author(s):  
Dana M. Hartl ◽  
Guillaume Landry ◽  
Stéphane Hans ◽  
Patrick Marandas ◽  
Odile Casiraghi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Anterior Commissure ◽  
Thyroid Cartilage ◽  
Cartilage Invasion

scholarly journals Rare presentation of gingival squamous cell carcinoma of maxillary posterior region mimicking pyogenic granuloma in a non-smoker – A case report

2021 ◽  
Vol 6 (3) ◽  
pp. 174-178
Author(s):  
R. Reshmaa ◽  
R. Kadhiresan ◽  
U. Arunmozhi ◽  
R. Shanmugapriya
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Examination ◽  
Malignant Neoplasm ◽  
Pyogenic Granuloma ◽  
Oral Carcinoma ◽  
Rare Presentation ◽  
Gingival Squamous Cell Carcinoma

Gingival Squamous cell carcinoma (GSCC) in maxilla is a rare malignant neoplasm especially when compared with mandible. The most common sites of oral carcinoma are being the lateral border of the tongue and the floor of the mouth which is followed by palate, buccal mucosa and rarely in gingiva. The clinical picture of oral carcinoma can be misguided for gingival overgrowth, desquamative lesions, traumatic ulcers or even pyogenic granuloma. Maxillary oral gingival carcinoma is a rare entity especially in a non-smoker. In this case report, a 70-year-old male patient presented with a gingival lesion in maxilla 24,25 region mimicking pyogenic granuloma without having a tobacco history. A thorough clinical, radiographical and histopathological examination was done and led to the diagnosis of GSCC and the treatment was initiated.Creating awareness among practitioners about gingival squamous cell carcinoma mimicking pyogenic granuloma in dental practice.

scholarly journals Primary squamous cell carcinoma of the thyroid-case report of a rare disease

2020 ◽  
Vol 4 (2) ◽  
pp. 01-04
Author(s):  
Lévay Bernadett
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vocal Cord Palsy ◽  
Neck Mass ◽  
Primary Squamous Cell Carcinoma ◽  
Adequate Treatment ◽  
Disease Case

Introduction: Primary squamous cell carcinoma (SCC) of the thyroid gland is a very rare entity. The prognosis is very poor with a short survival time. The aim of this article is to report a case of a SCC of the thyroid gland in a 68-year-old woman, emphasizing how complicate is the operation and the adequate treatment of this disease. Case Report: A 68-year -old woman presented with rapidly growing neck mass with hoarseness and compressive symptoms. Physical examination revealed a hard fixed tumor with right sided vocal cord palsy. Histopathological result confirmed the diagnosis of SCC of the thyroid. PET/CT scan excluded the possibility of other primary malignancies. A surgical intervention was performed, however the patient died in the middle of the palliative radiation therapy. Conclusion: SCC of the thyroid gland is a great challenge for the surgeon and also for the multidisciplinary team to come up with the best treatment option which is suitable for the patient due to its unfavorable prognosis.

scholarly journals Not all neck mass fine-needle aspirations with squamous cells are squamous cell carcinoma; report of a case of recurrent thyroid carcinoma with papillary and squamous components

CytoJournal ◽  
2018 ◽  
Vol 15 ◽  
pp. 23
Author(s):  
Katie Dennis ◽  
Maura O'Neil ◽  
Anthony Harrington
Keyword(s):  
Squamous Cell Carcinoma ◽  
Thyroid Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinical History ◽  
Needle Aspiration ◽  
Neck Mass ◽  
Braf V600e ◽  
Fine Needle ◽  
Poor Outcomes

We report a case of a 65-year-old female who had a total thyroidectomy 12 years ago for papillary thyroid carcinoma (PTC) who presented with a recurrent thyroid bed mass. Fine-needle aspiration biopsy yielded malignant cells, consistent with squamous cell carcinoma (SCCa). Surgical resection was performed, and histologic evaluation of the mass showed mixed PTC and SCCa. The tumor cells were positive for BRAF V600E mutation. Thyroid carcinomas with admixed papillary carcinoma and SCCa are rare and are associated with aggressive behavior, high rates of metastasis, and poor outcomes. Although SCCa presenting as a neck mass is relatively common, clinical history and appropriate workup are essential for accurate diagnosis and determination of origin.

scholarly journals Squamous Cell Carcinoma of the Thyroid Gland in an elderly Female

2021 ◽  
Vol 4 (3) ◽  
pp. 01-03
Author(s):  
Talal Mohammed Al-Shahr ◽  
Dema Wahid Hammami ◽  
Mutassem Jaber ◽  
Ghadeer Mazlooh Alenezi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cell Cancer ◽  
Radical Neck Dissection ◽  
Needle Aspiration ◽  
Neck Mass ◽  
Complete Excision ◽  
Clear Cases

Background: Squamous cell carcinoma of the thyroid gland is a rare tumor. The tumor may arise as a primary tumor within the thyroid gland. Case Presentation: A 62-years-old lady with history a history of a long-standing left neck mass presented with progressive enlargement of the mass for the last 2 months. The mass was associated with dyspnea, dry cough, and difficulty in swallowing but no change of voice. On examination, it was hard and fixed, and other parts of the general examination were unremarkable. Fine needle aspiration revealed malignant cells with squamous cell cancer (BETHESDA VI). On surgical exploration, there was a mixed cystic and solid mass arising from the left thyroid gland locally invading strap muscles, esophagus and trachea. Complete excision was not possible, debulking was done with modified radical neck dissection. The histopathology showed Invasive poorly differentiated squamous cell carcinoma of the thyroid with cystic changes in background of Hashimoto’s thyroiditis. Conclusion: Thyroid squamous cell carcinoma is a rare malignancy with significant management implications. Less than three hundred clear cases of thyroid squamous cell carcinoma have been reported. In this report we describe one additional case of a thyroid squamous cell carcinoma and provide a comprehensive discussion of the clinical significance, and appropriate surgical management.

scholarly journals Lymphoepithelial Cyst, A Diagnostic Dilemma: Case Report

2020 ◽  
Vol 7 (10) ◽  
pp. C137-140
Author(s):  
Meenu Gill ◽  
Sonia Chhabra ◽  
Sunita Singh ◽  
Dimple Mehrotra ◽  
Priyanka Rawat
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Examination ◽  
Excision Biopsy ◽  
Histopathological Diagnosis ◽  
Lymphoepithelial Cyst ◽  
Diagnostic Dilemma ◽  
Submandibular Region

Lymphoepithelial cysts are benign, slowly growing unilocular or multilocular lesions that appear in the head and neck region. They are also called branchial cysts and occur due to lymphocyte induced cystic ductular dilatation. The confirmatory diagnosis is always made on histopathological examination after resection. A 29 years old female patient presented to ENT department, Pt B. D. Sharma PGIMS, Rohtak with a soft to firm, non-tender, swelling in the submandibular region since 2 -3 days and was referred to Department of Pathology for FNAC on which a differential diagnosis of infected epidermoid cyst or squamous cell carcinoma was made and excision biopsy for confirmation and categorization was advised. The swelling was then excised and sent for histopathological examination and a final diagnosis of Lymphoepithelial cyst was made. The confirmatory diagnosis is always made postoperatively by histopathological examination. The treatment of a lymphoepithelial cyst is the surgical approach, which includes complete enucleation of the cyst. This is a case report of a lymphoepithelial cyst diagnosed on histopathology specimen for which differential of Infected cyst or Squamous cell carcinoma was given. The authors intend to highlight the importance of early histopathological diagnosis of Benign LEC as it has been reported to undergo malignant transformation

scholarly journals Primary Squamous Cell Carcinoma of the Thyroid Diagnosed as Anaplastic Carcinoma: Failure in Fine-Needle Aspiration Cytology?

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Fernanda Bolfi ◽  
Maria A. C. Domingues ◽  
Manuel Sobrinho-Simões ◽  
Paula Soares ◽  
Ricardo Celestino ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Examination ◽  
Hashimoto Thyroiditis ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Anaplastic Carcinoma ◽  
Primary Squamous Cell Carcinoma ◽  
Needle Aspiration Cytology

A case of primary squamous-cell carcinoma (SCC) of the thyroid which had been initially diagnosed as an anaplastic carcinoma (ATC) is described: female, 73 years old, with a fast-growing cervical nodule on the left side and hoarseness for 3 months. Ultrasonography showed a 4.5 cm solid nodule. FNA was compatible with poorly differentiated carcinoma with immunoreactivity for AE1/AE3, EMA. Thyroidectomy was performed. Histopathological examination showed a nonencapsulated tumor. Immunohistochemistry disclosed positivity for AE1/AE3, p53,p63, and Ki67. The diagnosis was ATC. A second opinion reported tumor consisting of squamous cells, with intense inflammatory infiltrate both in tumor and in the adjacent thyroid, with final diagnosis of SCC, associated with Hashimoto thyroiditis. No other primary focus of SCC was found. Patient has shown a 48-month survival period. Clinically, primary SCCs of the thyroid and ATCs are similar. The distinction is often difficult particularly when based on the cytological analysis of FNA material.

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