Backward masking task performance in stable, euthymic out-patients with bipolar disorder

2001 ◽  
Vol 31 (7) ◽  
pp. 1269-1277 ◽  
Author(s):  
G. M. MACQUEEN ◽  
L. T. YOUNG ◽  
T. M. GALWAY ◽  
R. T. JOFFE
Keyword(s):  
Bipolar Disorder ◽  
Target Stimulus ◽  
Burden Of Illness ◽  
Reaction Times ◽  
Error Rates ◽  
Neural Pathways ◽  
Backward Masking ◽  
Treatment Status ◽  
Dsm Iv ◽  
Visual Backward Masking

Background. Several studies have suggested that visual backward masking (VBM) impairment is present in patients with bipolar disorder, but the clinical features, such as current symptoms, treatment status and past burden of illness that may contribute to the impairment have not been well described. This study examined well-characterized euthymic patients on two VBM tasks to ascertain the extent of VBM impairment in this group and the clinical correlates of this impairment.Method. Twenty-eight euthymic patients with a DSM-IV diagnosis of bipolar disorder were matched by age, sex and IQ with 28 non-psychiatric control subjects. Both groups completed two VBM tasks; one required subjects to locate the target stimulus, one required identification of the target stimulus. Reaction times and error rates across a range of target-mask inter-stimulus intervals were assessed.Results. Patients were significantly slower and had more errors on both VBM tasks. There was a significant relation between reaction times on the identification task and past burden of illness, particularly past number of depressions. There was no discernible impact of treatment status on reaction time or performance, including no difference in lithium-treated versus not treated subjects.Conclusions. These results are consistent with previous reports of neuropsychological deficits in euthymic bipolar disorder patients. The potential benefit to employing tasks such as VBM is that it may provide a method for relating clinical variables such as illness burden with known neural pathways in order to elucidate better the pathophysiology leading to impaired cognitive performance in patients with bipolar disorder.

scholarly journals Electrophysiological correlates of visual backward masking in patients with bipolar disorder

2020 ◽  
Author(s):  
Simona Garobbio ◽  
Maya Roinishvili ◽  
Ophélie Favrod ◽  
Janir Ramos da Cruz ◽  
Eka Chkonia ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Global Field ◽  
Target Onset ◽  
Backward Masking ◽  
Global Field Power ◽  
Functional Psychoses ◽  
Visual Backward Masking

AbstractBackgroundIn visual backward masking (VBM), a target is followed by a mask that decreases target discriminability. Schizophrenia patients (SZ) show strong and reproducible masking impairments, which are associated with reduced EEG amplitudes. Patients with bipolar disorder (BP) show masking deficits, too. Here, we investigated the neural EEG correlates of VBM in BP.Methods122 SZ, 94 unaffected controls, and 38 BP joined a standard VBM experiment. 123 SZ, 94 unaffected controls and 16 BP joined a corresponding EEG experiment, analyzed in terms of the global field power.ResultsAs in previous studies, SZ and BP show strong masking deficits. Importantly and similarly to SZ, BP show decreased global field power amplitudes at approximately 200 ms after the target onset, compared to controls.ConclusionsThese results suggest that VBM deficits are not specific for schizophrenia but for a broader range of functional psychoses. Potentially, both SZ and BP show deficient target enhancement.

scholarly journals Computerized Stroop Test to Assess Selective Attention in Children with Attention Deficit Hyperactivity Disorder

2007 ◽  
Vol 10 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Ellen Carolina dos Santos Assef ◽  
Alessandra Gotuzo Seabra Capovilla ◽  
Fernando Cesar Capovilla
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Selective Attention ◽  
Cognitive Flexibility ◽  
Attention Deficit ◽  
Target Stimulus ◽  
Reaction Times ◽  
Stroop Test ◽  
Children With Adhd ◽  
Hyperactivity Disorder ◽  
Dsm Iv

Research shows abnormal function of the pre-frontal cortex in Attention Deficit Hyperactivity Disorder (ADHD). This cortex is involved in the control of executive functions related to planning and execution of goal-oriented strategies, working memory, inhibitions, cognitive flexibility, and selective attention. Selective attention involves focus on the target stimulus, ignoring competing distractions. The Stroop Test (Stroop, 1935) is usually used to evaluate selective attention. This study investigated whether children with ADHD could exhibit modified performance in the Stroop Test. Using a computerized version of this test (Capovilla, Montiel, Macedo, & Charin, 2005), the study compared the reaction times (RTs) of 62 Brazilian children, between 8 and 12 years of age, 31 of whom were diagnosed with ADHD and sent to psychiatric clinics, and 31 without ADHD studying in regular schools. All children with ADHD satisfied the criteria of the DSM-IV-TR and were evaluated with the Conners Abbreviated Questionnaire (Goyette, Conners, & Ulrich, 1978), completed by parents and teachers. The results revealed that children with ADHD exhibit greater interference in RT than children without ADHD. This corroborated the hypothesis that children with ADHD exhibit a deficit in selective attention, consisting in augmented RTs, as measured by the Computerized Stroop Test.

Effect of Practice on Visual Backward Masking

1980 ◽  
Vol 50 (2) ◽  
pp. 511-517
Author(s):  
David Braff ◽  
Dennis Saccuzzo ◽  
Rick Ingram ◽  
Brian Mc Neill ◽  
Richard Langford
Keyword(s):  
Signal Detection ◽  
Stimulus Duration ◽  
Target Stimulus ◽  
Practice Effects ◽  
Backward Masking ◽  
Considerable Variability ◽  
Pattern Mask ◽  
Critical Stimulus ◽  
Visual Backward Masking ◽  
Made In

Five experiments studied practice effects for 4, 7, 11 subjects on visual backward masking using a signal-detection procedure under various conditions. Exp. I determined the minimum perceptible critical stimulus duration (CSD) for criterion identification of a target stimulus, the letter T or A. In Exp. II, the stimulus was presented at the critical stimulus duration (CSD) followed by a pattern mask at intervals of 20 to 120 msec. for 15 separate sessions. In Exp. III ( N = 4) the mask followed the CSD in intervals of 2-msec. increments until subjects reached criterion accuracy. Exps. IV and V ( Ns = 4, 7) provided partial replications of Exps. II and III. Naive subjects were used, and the stimulus duration was constant for all subjects. When masking functions were obtained at a threshold, considerable variability was found and subjects improve slowly or not at all over sessions. With a fixed suprathreshold stimulus, all subjects improve with practice. The importance of these findings is discussed as they relate to common (and largely untested) assumptions made in the backward masking and perception literature.

scholarly journals Electrophysiological correlates of visual backward masking in patients with bipolar disorder

2021 ◽  
Vol 307 ◽  
pp. 111206
Author(s):  
Simona Garobbio ◽  
Maya Roinishvili ◽  
Ophélie Favrod ◽  
Janir Ramos da Cruz ◽  
Eka Chkonia ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Backward Masking ◽  
Visual Backward Masking

A pilot study of visual backward masking performance among affected versus unaffected offspring of parents with bipolar disorder

2004 ◽  
Vol 6 (5) ◽  
pp. 374-378 ◽  
Author(s):  
Glenda M MacQueen ◽  
Paul Grof ◽  
Martin Alda ◽  
Michael Marriott ◽  
L Trevor Young ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Pilot Study ◽  
Backward Masking ◽  
Visual Backward Masking

Twelve-month prevalence and disability of DSM-IV bipolar disorder in an Australian general population survey

2004 ◽  
Vol 34 (5) ◽  
pp. 777-785 ◽  
Author(s):  
P. B. MITCHELL ◽  
T. SLADE ◽  
G. ANDREWS
Keyword(s):  
Bipolar Disorder ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
National Survey ◽  
Large Scale ◽  
Well Being ◽  
Major Depressive ◽  
Co Morbidity ◽  
Dsm Iv ◽  
Days Out Of Role

Background. There have been few large-scale epidemiological studies which have examined the prevalence of bipolar disorder. The authors report 12-month prevalence data for DSM-IV bipolar disorder from the Australian National Survey of Mental Health and Well-Being.Method. The broad methodology of the Australian National Survey has been described previously. Ten thousand, six hundred and forty-one people participated. The 12-month prevalence of euphoric bipolar disorder (I and II) – similar to the euphoric-grandiose syndrome of Kessler and co-workers – was determined. Those so identified were compared with subjects with major depressive disorder and the rest of the sample, on rates of co-morbidity with anxiety and substance use disorders as well as demographic features and measures of disability and service utilization. Polychotomous logistic regression was used to study the relationship between the three samples and these dependent variables.Results. There was a 12-month prevalence of 0·5% for bipolar disorder. Compared with subjects with major depressive disorder, those with bipolar disorder were distinguished by a more equal gender ratio; a greater likelihood of being widowed, separated or divorced; higher rates of drug abuse or dependence; greater disability as measured by days out of role; increased rates of treatment with medicines; and higher lifetime rates of suicide attempts.Conclusions. This large national survey highlights the marked functional impairment caused by bipolar disorder, even when compared with major depressive disorder.

Patients with functional psychoses show similar visual backward masking deficits

2012 ◽  
Vol 198 (2) ◽  
pp. 235-240 ◽  
Author(s):  
Eka Chkonia ◽  
Maya Roinishvili ◽  
Liza Reichard ◽  
Wenke Wurch ◽  
Hendrik Puhlmann ◽  
...  
Keyword(s):  
Backward Masking ◽  
Functional Psychoses ◽  
Visual Backward Masking
Sign in / Sign up

Export Citation Format

Share Document