scholarly journals 3. Histological Observations on the Muscle, Fibre, and Connective Tissue of the Uterus during Pregnancy and the Puerperium

1889 ◽  
Vol 15 ◽  
pp. 435-435
Author(s):  
T. A. Helme ◽  
Woodhead
animal ◽  
2020 ◽  
Vol 14 (6) ◽  
pp. 1204-1212 ◽  
Author(s):  
A. Listrat ◽  
M. Gagaoua ◽  
J. Normand ◽  
D.J. Andueza ◽  
D. Gruffat ◽  
...  

1996 ◽  
Vol 148 (2) ◽  
pp. 337-346 ◽  
Author(s):  
J M Oldham ◽  
J A K Martyn ◽  
S P Kirk ◽  
J R Napier ◽  
J J Bass

Abstract The relative abundance and location of type 1 IGF receptors in sheep muscles have been measured to determine whether changes occur during post-natal growth and nutritional stress. Using the technique of histological autoradiography, specific binding of 125I-IGF-I in muscle fibre and connective tissue of M. biceps femoris and M. gastrocnemius was demonstrated, as was specific binding to the tendon of M. gastrocnemius and the surrounding connective tissue. The binding site in both muscles was characterised as the type 1 IGF receptor in membrane preparations using competitive binding assay and SDS-PAGE. Type 1 receptors were more abundant in connective tissue than muscle fibre or tendon (P≤0·001). Levels changed significantly with age in all tissues (P=0·054 to P≤ 0·001), while change as a result of fasting was limited to a receptor increase in the connective tissue of M. gastrocnemius (P=0·034). IGF-I mRNA in M. bicepsfemoris, as assessed by in situ hybridisation, showed changes in expression with increasing age (P≤ 0·025) but no change with fasting. These data indicate that the distribution, relative abundance and nutritional sensitivity of type 1 receptors are related to cell type in vivo. The overall decline of receptors with increasing age may be a feature of transition from linear animal growth to cell maintenance in adult animals. Connective tissue appears to be more sensitive than muscle fibre to nutrition, possibly allowing the reduction of non-essential metabolism during fasting. Journal of Endocrinology (1996) 148, 337–346


1962 ◽  
Vol s3-103 (62) ◽  
pp. 227-242
Author(s):  
M. P. OSBORNE ◽  
L. H. FINLAYSON

In Ephemera (Ephemeroptera), Dictyopterygella and Isoperla (Plecoptera), Periplaneta and Blaberus (Dictyoptera), Forficula (Dermaptera), and Dytiscus (Coleoptera) there is a pair of stretch receptors on each side in the dorsal region of most abdominal segments. Each receptor consists of a connective-tissue strand to which is attached a single sensory neuron. One member of each pair is approximately longitudinal and the other approximately vertical in orientation. In Sialis (Neuroptera-Megaloptera) the longitudinal receptor consists of a musclefibre and a neuron; the vertical receptor consists of a neuron with one or two long processes. Connective-tissue fibres are absent from both receptors. In Limnophilus and Phryganea (Trichoptera) there is a longitudinal receptor only. It consists of a muscle-fibre to which is attached a tube of connective tissue containing the dendrites of the sensory neuron. The caddis receptor resembles closely the lepidopteran receptor. No abdominal stretch receptors could be found in Rhodnius or Nepa (Hemiptera-Heteroptera), and in Schistocerca and Locusta (Orthoptera) no vertical receptors could be found.


2020 ◽  
pp. 4537-4546
Author(s):  
Ingrid E. Lundberg ◽  
Hector Chinoy ◽  
Robert Cooper

The idiopathic inflammatory myopathies are a heterogenous group of disorders characterized by muscle weakness, inflammation in muscle tissue, and with frequent extramuscular involvement. Autoantibodies are common, supporting the notion of these disorders being autoimmune. Typically, inflammatory cell infiltrates are found in muscle biopsies. Other organs are frequently involved such as skin, lungs, joints, gastrointestinal tract, and the heart. These heterogenous disorders can be subclassified based on clinical and histopathological features, or by autoantibody specificities. The idiopathic inflammatory myopathies have traditionally comprised polymyositis (PM), dermatomyositis (DM), juvenile DM, PM/DM overlapping with another connective tissue disease, and inclusion body myositis. More recently a subgroup with similar clinical features but with no or scarce inflammation and with pronounced muscle fibre necrosis has been identified and termed immune-mediated necrotizing myopathy.


1972 ◽  
Vol 181 (1065) ◽  
pp. 431-440 ◽  

1. The acetylcholine (ACh) sensitivity of muscle fibres at the neuromuscular junction of the frog was investigated in preparations in which the nerve terminals could be clearly seen. 2. ACh released iontophoretically from a micropipette that was precisely positioned at various points along the muscle fibre in the vicinity of the synapse showed that the peak chemosensitivity (up to 1900 mV/nC) is confined to an area of postsynaptic membrane within a few micra of the nerve terminal; a tenfold decline in sensitivity was obtained when the ACh was released only 5 to 10 μm from the terminal’s edge. It is estimated that most of the response obtained when ACh is released within 40 μm from the terminal (the area covered in this study) is due to diffusion to the immediate postsynaptic area. The extrasynaptic chemosensitivity of the muscle membrane was too low to be measured with the present methods. 3. The accuracy with which micropipettes could be positioned in synaptic areas and the clarity of viewing nerve terminals were improved by bathing the tissue in collagenase, which reduced the amount of connective tissue. The distribution of chemosensitivity remained unchanged by such treatment. The ACh response was not detectably altered when nerve terminals were lifted off the muscle, exposing the subsynaptic muscle surface.


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