scholarly journals Surgical Approaches Based on Biological Objectives: GTR versus GBR Techniques

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Gaia Pellegrini ◽  
Giorgio Pagni ◽  
Giulio Rasperini

Guided tissue regenerative (GTR) therapies are performed to regenerate the previously lost tooth supporting structure, thus maintaining the aesthetics and masticatory function of the available dentition. Alveolar ridge augmentation procedures (GBR) intend to regain the alveolar bone lost following tooth extraction and/or periodontal disease. Several biomaterials and surgical approaches have been proposed. In this paper we report biomaterials and surgical techniques used for periodontal and bone regenerative procedures. Particular attention will be adopted to highlight the biological basis for the different therapeutic approaches.

Author(s):  
J. S. Hanker ◽  
B. L. Giammara

Nonresorbable sintered ceramic hydroxylapatite (HA) is widely employed for filling defects in jaw bone. The small particles used for alveolar ridge augmentation in edentulous patients or for infrabony defects due to periodontal disease tend to scatter when implanted using water or saline as the vehicle. Larger blocks of this material used for filling sockets after tooth extraction don't fit well. Studies in our laboratory where we compared bovine serum albumin, collagen and plaster of Paris as binders to prevent particle scatter during implantation suggested that plaster was most useful for this purpose. In addition to preventing scatter of the particles, plaster enables the formation of implants of any size and.shape either prior to or during surgery. Studies with the PATS reaction have indicated that plaster acts as a scaffold for the incorporation of HA particles into bone in areas where the implant contacts either host bone or periosteum. The shape and integrity of the implant is maintained by the plaster component until it is replaced over a period of days by fibrovascular tissue.


Author(s):  
J. S. Hanker ◽  
D. A. Randolph ◽  
B. L. Giammara ◽  
P. E. Yates ◽  
R. G. Lange

Nonresorbable sintered hydroxylapatite (HA) particles are widely used for alveolar ridge augmentation in edentulous patients to support dentures or for filling infrabony defects due to bone resorption in progressive periodontal disease. these particles tend to scatter when implanted with water or saline as the vehicle. studies in our laboratory of different binders to prevent particle scatter during implantation suggested the utility of plaster of paris for this purpose. In most operative procedures the ha/plaster mixtures moistened with water or saline set and harden adequately, especially when a small amount of potassium sulfate has been added to the plaster component to accelerate setting. when the implantation site is bloody or has an excess of tissue fluids, setting of the mixture is considerably slowed if, indeed, the plaster is not actually washed away.


2014 ◽  
Vol 614 ◽  
pp. 89-94 ◽  
Author(s):  
Cena Dimova ◽  
Kiro Papakoca ◽  
Velko Papakoca

Bones and teeth are the only structureswithin the body where calciumandphosphate participate asfunctional pillars. Despite their mineralnature, both organs are vital and dynamic. The aim was to remark the indications for alveolar augmentation after tooth extraction and prior the placement of endoosseous dental implants. The autograft, allograft, alloplast, and xenograftmaterials all have reported success, alone or in combination,for particulate bone augmentation. Theparticulate autograft is the gold standard for mostcraniofacial bone grafting, including the treatmentof dental implant–related defects. Advantages of alveolar ridge augmentation with sufficient bone volume to adjust for uncompromised and esthetic implant placement, renders these procedures more than effective for majority of patients. Surgical reconstruction of the tissues and the procedure of ridge augmentation and subsequent placement of dental implant are necessary.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Masahiro Nishimura ◽  
Kazuma Takase ◽  
Fumio Suehiro ◽  
Hiroshi Murata

Most of the cases of dental implant surgery, especially the bone defect extensively, are essential for alveolar ridge augmentation. As known as cell therapy exerts valuable effects on bone regeneration, numerous reports using various cells from body to regenerate bone have been published, including clinical reports. Mesenchymal cells that have osteogenic activity and have potential to be harvested from intra oral site might be a candidate cells to regenerate alveolar bone, even dentists have not been harvested the cells outside of mouth. This paper presents a summary of somatic cells in edentulous tissues which could subserve alveolar bone regeneration. The candidate tissues that might have differentiation potential as mesenchymal cells for bone regeneration are alveolar bone chip, bone marrow from alveolar bone, periosteal tissue, and gingival tissue. Understanding their phenotype consecutively will provide a rational approach for alveolar ridge augmentation.


2015 ◽  
Vol 16 (9) ◽  
pp. 768-773 ◽  
Author(s):  
Mogammad Thabit Peck

ABSTRACT Background The loss of teeth, whether it is from trauma or pathology, is accompanied by a concomitant loss of the surrounding alveolar bone. Khoury introduced a new method for grafting ridge defects in 2007. This technique involved using thin cortical plates harvested from the ramus, and in a ‘sandwich’ type manner, interposed these bone plates with cancellous bone harvested from the same site. Although this has shown success, the technique suffers from similar disadvantages of most harvesting techniques, i.e. a need for a second surgical site, and donor site morbidity. In this case presentation, we report the use of an allograft bone plate in a similar manner as was previously described by Khoury, to reconstruction lost alveolar bone in order to facilitate the correct three dimensional (3D) placement of dental implants. Case description A 53-year-old female presented for the restoration of her missing dentition in her upper jaw. The cone bean computed tomography (CBCT) revealed a large horizontal bony defect in the region of the upper anterior teeth, with minimal remaining bone. Using bone fixation screws, the bone plates were fixed to the buccal defect and the space between the plate and the existing palatal bone wall was then filled using a combination of autograft bone scrapings and xenograft bone particles. Six months after the initial surgery, the grafted sites were surgically re-entered and showed a marked increase in ridge width. Conclusion Evidence exists for the use of bone allografts for a variety of alveolar bone augmentation procedures. The case presented outlines another use for this versatile biomaterial. Clinical significance Bone harvesting for large alveolar defects is invariably associated with increased morbidity and an increased risk of postoperative complications. The above technique described by the author, may be used as a suitable alternative to reconstruct these defects, without harvesting bone from a second surgical site. How to cite this article Peck MT. Alveolar Ridge Augmentation using the Allograft Bone Shell Technique. J Contemp Dent Pract 2015;16(9):768-773.


Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3286
Author(s):  
Hotaka Kawai ◽  
Shintaro Sukegawa ◽  
Keisuke Nakano ◽  
Kiyofumi Takabatake ◽  
Sawako Ono ◽  
...  

The purpose of this study was to investigate the bone healing properties and histological environment of a u-HA/PLLA/PGA (u-HA—uncalcined and unsintered hydroxyapatite, PLLA—Poly L-lactic acid, PGA—polyglycolic acid) composite device in humans, and to understand the histological dynamics of using this device for maxillofacial treatments. Twenty-one subjects underwent pre-implant maxillary alveolar ridge augmentation with mandibular cortical bone blocks using u-HA/PLLA or u-HA/PLLA/PGA screws for fixation. Six months later, specimens of these screws and their adjacent tissue were retrieved. A histological and immunohistochemical evaluation of these samples was performed using collagen 1a, ALP (alkaline phosphatase), and osteocalcin. We observed that alveolar bone augmentation was successful for all of the subjects. Upon histological evaluation, the u-HA/PLLA screws had merged with the bone components, and the bone was directly connected to the biomaterial. In contrast, direct bone connection was not observed for the u-HA/PLLA/PGA screw. Immunohistological findings showed that in the u-HA/PLLA group, collagen 1a was positive for fibers that penetrated vertically into the bone. Alkaline phosphatase was positive only in the u-HA/PLLA stroma, and the stroma was negative for osteocalcin. In this study, u-HA/PLLA showed a greater bioactive bone conductivity than u-HA/PLLA/PGA and a higher biocompatibility for direct bone attachment. Furthermore, u-HA/PLLA was shown to have the potential for bone formation in the stroma.


2020 ◽  
Author(s):  
Melike Aytekin ◽  
Volkan Arisan

Implant supported restorations have become an ideal treatment alternative for the rehabilitation of edentulous sites. However alveolar bone defects due to resorption, trauma or oncologic diseases may considerably affect favorable implant positioning and prosthetic outcomes. Various alveolar ridge augmentation procedures are available to gain enough bone volume and apply the ideal treatment plan afterwards. Guided bone regeneration, ridge splitting, distraction osteogenesis, maxillary sinus augmentation and autogenous block bone grafting are main techniques which have successful outcomes in reconstruction of bone defects. It’s difficult to demonstrate that one augmentation procedure offers better outcomes than another. Studies documenting augmentation techniques seem to be comparable and state favorable results for each procedure.


Author(s):  
Kai-Fang Hu ◽  
Ying-Chu Lin ◽  
Yu-Ting Huang ◽  
Yu-Hsiang Chou

Abstract Objectives The aim of this study was to assess whether alveolar ridge preservation (ARP) can reduce the need of ridge augmentation at posterior tooth sites. Material and methods This study enrolled patients who received dental implants at posterior tooth sites during 2013–2019. Demographic data and dental treatment histories were collected. Based on healing patterns after tooth extraction, patients were divided into ARP and spontaneous healing (SH) groups. Three surgical treatment plans were devised according to the alveolar bone volume on cone-beam computed tomography (CBCT). The three treatment plans were to perform implant alone, simultaneous guided bone regeneration (GBR) and implantation, and staged GBR before implantation. Statistical analyses were performed to determine relationships. Results There were 92 implant records in the ARP group and 249 implant records in the SH group. A significant intergroup difference was observed regarding the frequency distribution of the treatment modality of staged GBR before implant (χ2 = 15.07, p = 0.0005). Based on the implant alone treatment modality and simple logistic regression, the SH pattern was related to staged GBR before implant (SH vs. ARP: crude odds ratio (OR) = 4.65, 95% confidence interval (CI) = 2.15–11.61, p = 0.0003). After adjusting confounding factors, the risk was still significant (adjusted OR = 5.02, 95% CI = 2.26–12.85, p = 0.0002). Conclusions The study results suggested that ARP is more likely to lead to the treatment modality of implant alone and reduce the need for staged GBR before implantation. Clinical relevance This study describes ARP capable of minimizing the need for staged GBR before implantation and shortening the treatment duration.


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