scholarly journals Methicillin-resistant Staphylococcus aureus in the community in West Essex

2005 ◽  
Vol 134 (2) ◽  
pp. 301-305 ◽  
Author(s):  
S. MILLERSHIP ◽  
J. HARRIS ◽  
N. BATCHELOR
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Clinical Presentation ◽  
Care Homes ◽  
Microbiology Laboratory ◽  
Local Hospital ◽  
Methicillin Resistant ◽  
Diagnostic Microbiology ◽  
Hospital Acquired ◽  
Hospital Contact

The study was undertaken in response to local concerns of a rising number of community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections. All patients resident in the community in Essex at the time of diagnosis with a first isolate of MRSA between 1994 and 2001 identified by the diagnostic microbiology laboratory were included. Although the annual incidence rose throughout the study period the majority of those with MRSA (82%) had had hospital contact within the last 5 years. The subset of patients without hospital contact had a median age of 79·5 years, 63% were female and 32% were residents of care homes. Carriage in this population was detected for up to 41 months post-diagnosis. Neither antibiogram nor clinical presentation distinguished these isolates from local hospital-acquired strains.

scholarly journals Methicillin Resistant Staphylococcus aureus: Prevalence And Antibiogram In A Tertiary Care Hospital in Western Nepal

2009 ◽  
Vol 3 (09) ◽  
pp. 681-684 ◽  
Author(s):  
Hare Krishna Tiwari ◽  
Ayan Kumar Das ◽  
Darshan Sapkota ◽  
Kunjukunju Sivrajan ◽  
Vijay Kumar Pahwa
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Inhibitory Concentration ◽  
Tertiary Care ◽  
Care Hospital ◽  
Methicillin Resistant ◽  
Mrsa Strains ◽  
Susceptibility Tests ◽  
Rational Use Of Antibiotics ◽  
Hospital Acquired

Background: Methicillin resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial and community infections. Its prevalence varies with country and with hospitals within a country. The current study estimates the prevalence of MRSA strains and investigates their antibiogram in western Nepal. Methodology: A total of 162 S. aureus strains were isolated from various clinical specimens, and antibiotic susceptibility tests were performed using disc diffusion, growth on oxacillin screen agar, and oxacillin minimum inhibitory concentration (MIC). Results: One hundred and twelve (69.1%) strains were found to be MRSA, of which 37 (33.1%) were community acquired and 75 (66.9%) were hospital acquired. Of 112 MRSA strains, 45 (40.1%) were multi-drug resistant. All MRSA strains were found resistant to penicillin, and 91.9%, 87.4%, 77%, and 55.5% were resistant to amoxicillin, ampicillin, trimethoprim/sulfamethoxazole, and cephalexin, respectively. However, low resistance was observed with amikacin (19%), ciprofloxacin (26.5%), and norfloxacin (30.6%). All strains were sensitive to vancomycin. Conclusion: The reported rate of MRSA prevalence is alarming. Given the ability of MRSA to spread from person to person, it is necessary to adhere to rational use of antibiotics and to raise awareness among the concerned communities and tourists who visit this area.

scholarly journals In Vitro Killing of Community-Associated Methicillin-Resistant Staphylococcus aureus with Drug Combinations

2004 ◽  
Vol 48 (10) ◽  
pp. 4016-4019 ◽  
Author(s):  
Samuel A. Shelburne ◽  
Daniel M. Musher ◽  
Kristina Hulten ◽  
Heather Ceasar ◽  
Michael Y. Lu ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Drug Combinations ◽  
Methicillin Resistant ◽  
Common Drug ◽  
Time Kill ◽  
Hospital Acquired

ABSTRACT This study employs time-kill techniques to examine the most common drug combinations used in the therapy of methicillin-resistant Staphylococcus aureus (MRSA) infections, vancomycin plus either gentamicin or rifampin. Community-associated MRSA were more likely to be synergistically inhibited by combinations of vancomycin and gentamicin versus vancomycin alone compared to inhibition associated with hospital-acquired strains.

Intravenous Antibiotics Used in the Treatment of Methicillin-Resistant Staphylococcus Aureus

2015 ◽  
Vol 26 (3) ◽  
pp. 233-243
Author(s):  
Kristine Anne Scordo
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Multidrug Resistant ◽  
Medical Procedures ◽  
Term Care ◽  
Methicillin Resistant ◽  
Intravenous Antibiotics ◽  
Resistant Strains ◽  
Hospital Acquired

Methicillin-resistant Staphylococcus aureus (MRSA) continues to cause significant morbidity and mortality. Despite advances in medical care, the prevalence of both community-acquired and hospital-acquired MRSA has progressively increased. Community-acquired MRSA typically occurs in patients without recent illness or hospitalization, presents as acute skin and soft tissue infections, and is usually not multidrug resistant. Hospital-acquired MRSA, however, presents in patients recently hospitalized or treated in long-term care settings and in those who have had medical procedures and is usually associated with multidrug-resistant strains. Both types of infections, if not properly treated, have the potential to become invasive. This article discusses current intravenous antibiotics that are available for the empiric treatment of MRSA infections along with a newer phenomenon known as the “seesaw effect.”

Epidemiology and Risk Factors for Hospital-Acquired Methicillin-Resistant Staphylococcus aureus Among Burn Patients

2011 ◽  
Vol 32 (3) ◽  
pp. 429-434 ◽  
Author(s):  
Meghann L. Kaiser ◽  
Deborah J. Thompson ◽  
Darren Malinoski ◽  
Christopher Lane ◽  
Marianne E. Cinat
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Burn Patients ◽  
Methicillin Resistant ◽  
Hospital Acquired
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