Left ventricular fibroma in two children

1997 ◽  
Vol 7 (4) ◽  
pp. 462-464
Author(s):  
Chan Uhng Joo ◽  
Kong Soo Kim ◽  
Hyang Suck Yoon

AbstractPrimary cardiac tumors are rare in infancy and childhood. We describe the features of large intramural ventricular cardiac fibromas discovered in two children. In the first, a left ventricular apical tumor was discovered by means of echocardiography and left ventriculography in a symptomless 8-year-old boy. The intramural fibroma was successfully resected. In the other case, an 8-month-old female infant with severe congestive heart failure, sudden ventricular tachycardia and fibrillation occurred during left ventriculography. At necropsy a tumor was seen bulging in the anterior wall of the left ventricle and in the ventricular septum. Histology showed the tumor to be a fibroma.

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Eiichiro Yamamoto ◽  
Keisuke Ohba ◽  
Yoshihiro Hirata ◽  
Takanori Tokitsu ◽  
Koichi Sugamura ◽  
...  

Introduction: The optimal treatment for heart failure (HF) with preserved left ventricular (LV) ejection fraction (EF) (HFpEF) has not been established. Using an experimental model of HFpEF, we previously reported a novel mechanism underlying reversal of endothelial dysfunction and HFpEF by AT1 receptor blocker (ARB). By performing this study (ORION: OlmesaRtan Improvement endothelial functiON with hypertension study), we examined the effects of ARB on hypertensive HFpEF patients, focusing on reactive oxygen species (ROS). Methods and Results: We examined prospectively 20 hypertensive HFpEF patients, taking any renin-angiotensin system inhibitors, switched to appreciable amounts of highly-selective ARB; olmesartan (average dosage amounts: 22.9 mg/day) for 3 months. Despite no additive hypotensive effects of olmesartan, endothelial dysfunction assessed by fingertrip digital reactive hyperemia (RH) peripheral arterial tonometry using Endo-PAT2000 was significantly reversed (RH-index; 1.57±0.34 to 1.87±0.50, P=0.034), accompanied by significant reduction of serum derivatives of reactive oxidative metabolites levels, novel biomarker of ROS (362.8±13.7 to 302.1±9.4 unit called the Carratelli unit [U.CARR], P=0.001). Olmesartan treatments significantly improved cardiac diastolic function evaluated by the ratio of early transmitral flow velocity to tissue doppler early diastolic mitral annular velocity (15.4 to 11.0, P<0.001) but not LVEF and LV anterior wall thickness in echocardiography, and decreased plasma B-type natriuretic peptide levels (214.9 to 191.4, P<0.05) in HFpEF patients. Additionaly, olmesartan significantly increased plasma superoxide dismutase activity (2.39±0.73 to 3.06±0.78 U/mL, P=0.02) and adiponectin levels (2.66±1.55 to 4.12±1.99 μg/mL, P<0.05), but not affect plasma nitrates and nitrites (NO3-/NO2-) levels (53.2±28.1 to 62.9±28.4 μmol/L). Conclusions: These data suggested that strong AT1 receptor blockade by olmesartan restored not only endothelial dysfunction but cardiac diastolic dysfunction in HFpEF beyond hypotensive effects. Increased in SOD activities and adiponectin levels, but not nitric oxide levels, might contribute to these beneficial effects of olmesartan.


Author(s):  
Du Le Ba Minh

Objective: Prenatal diagnosis, postnatal followed up of three cases of cardiac tumor and successful postnatal surgery of one case. Methods: Treatment and postnatal followed up of three cases of cardiac tumor. Those cases were diagnosed by fetal echocardiography. One of them underwent a successful postnatal surgery. Results: Three fetuses were diagnosed with fetal cardiac tumor (capable of Rhabdomyoma) at 28, 27, 38 gestational weeks. There were many tumors in one or two ventricles. These cases were referred to Hue Central Hospital for timing and location of delivery in 2019. One of them had obstruction of left ventricular outflow tract with successful surgical resection at 46 hours after birth. One of them had heart failure after birth. Evolution of three cases was favorable, heart failure regressed, cardiac tumors regressed at 7 - 9 months follow up. Conclusions: Fetal cardiac tumor can be diagnosed prenatally. Those three cases were capable of rhabdomyoma due to the presence of muliple tumors and their regression after birth. Neonatal surgical option should be reserved for the risk of cardiac flow obstruction.


2005 ◽  
Vol 4 (4) ◽  
pp. 314-323 ◽  
Author(s):  
Margareta Brännström ◽  
Christine Brulin ◽  
Astrid Norberg ◽  
Kurt Boman ◽  
Gunilla Strandberg

Advanced homecare for persons with congestive heart failure is a ‘new’ challenge for palliative nurses. The aim of this study is to illuminate the meaning of being a palliative nurse for persons with severe congestive heart failure in advanced homecare. Narrative interviews with 11 nurses were conducted, tape-recorded, and transcribed verbatim. A phenomenological-hermeneutic method was used to interpret the text. One meaning of being a palliative nurse is being firmly rooted and guided by the values of palliative culture. Being adaptable to the patient's way of life carries great weight. On one hand nurses live out this value, facilitating for the patients to live their everydaylife as good as possible. Being a facilitator is revealed as difficult, challenging, but overall positive. On the other hand nurses get into a tight corner when values of palliative culture clash and do not correspond with the nurses interpretation of what is good for the person with congestive heart failure. Being in such a tight corner is revealed as frustrating and giving rise to feelings of inadequacy. Thus, it seems important to reflect critical on the values of palliative culture.


1998 ◽  
Vol 8 (1) ◽  
pp. 126-127 ◽  
Author(s):  
A. Kapoor ◽  
S. Radhakrishnan ◽  
N. Sinha

AbstractAmongst all primary cardiac tumors, myxomas are the commonest, and their commonest site of origin is the left atrium. Myxomas originating in the left ventricle are rare. When seen, they usually present with a history of systemic embolisation and/or syncopal episodes, with constitutional symptoms being absent. We report here a child with left ventricular myxoma who presented with a prolonged febrile illness.


Pulse ◽  
2018 ◽  
Vol 10 (1) ◽  
pp. 29-33
Author(s):  
T Meher ◽  
SMAZN Palash ◽  
MK Hasan ◽  
TMNS Khan ◽  
NM Zahangir ◽  
...  

Atrial Myxoma is the most common primary cardiac tumors accounting for about 50% of benign primary cardiac tumors, with the majority located in the left atrium. This is a case of large left atrial (LA) myxoma presented with features of mitral stenosis associated with moderate left ventricular failure (LVF) and mild pulmonary artery hypertension (PAH) The patient improved markedly after tumor excision.Pulse Vol.10 January-December 2017 p.29-33


2016 ◽  
Vol 10 (2) ◽  
pp. 151
Author(s):  
Kyriacos Papadopoulos ◽  
Constantinos Makrides

Myocardial perfusion contrast echocardiography is an imaging tool for the assessment of myocardial microcirculation. It can also be used for the evaluation of the relative perfusion of a cardiac mass. Cardiac hemangiomas are rare tumors, accounting for only 2.8% of all benign primary cardiac tumors. We report a case of a 17-year-old man with a left ventricular hemangioma detected with transthoracic echocardiography. Myocardial perfusion contrast echocardiography was used to evaluate the vascularity of the cardiac mass. Using this technique malignant and hypervascular (<em>e.g</em>., hemangioma) tumors display persistence of contrast enhancement compared to the surrounding myocardium. The mass was successfully removed and the final report from pathology showed that the left ventricular mass was a hemangioma, a hypervascular tumor


Sign in / Sign up

Export Citation Format

Share Document