scholarly journals Prevalence of thyroid dysfunction with adequate and excessive iodine intake in Hebei Province, People’s Republic of China

2014 ◽  
Vol 18 (9) ◽  
pp. 1692-1697 ◽  
Author(s):  
Long Tan ◽  
Zhongna Sang ◽  
Jun Shen ◽  
Hua Liu ◽  
Wen Chen ◽  
...  
Keyword(s):  
Drinking Water ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Iodine Concentration ◽  
Iodine Intake ◽  
Hebei Province ◽  
People's Republic Of China ◽  
Republic Of China ◽  
Excessive Iodine ◽  
Excessive Iodine Intake

AbstractObjectiveTo explore (i) the prevalence of thyroid dysfunction in populations with adequate and excessive iodine intakes and (ii) the effect of iodine exposure on the prevalence of thyroid dysfunction.DesignCross-sectional study was conducted in Hebei in 2010. The population was classified as having adequate or excessive iodine intake according to the iodine concentration in drinking water. Demographic information was collected by questionnaire. Levels of serum thyroid hormones, thyroid autoantibodies and iodine in drinking water and urine were measured.SettingVillages with adequate or excessive drinking water iodine in Hebei Province, People’s Republic of China.SubjectsA total of 854 men and women aged 20–50 years who had lived in the surveyed areas for over 5 years, including 348 from the adequate iodine area (AIA) and 506 from the excessive iodine area (EIA).ResultsMedian urinary iodine concentration was 185 μg/l in AIA and 1152 μg/l in EIA. The prevalence of thyroid dysfunction in AIA was 10·3 %, which included 1·1 % with hypothyroidism and 8·1 % with subclinical hypothyroidism; and 20·6 % in EIA, which included 3·6 % with hypothyroidism and 13·6 % with subclinical hypothyroidism. The positive rates of thyroglobulin antibody were 16·1 % in AIA and 11·9 % in EIA; the positive rates of thyroperoxidase antibody were 20·7 % in AIA and 16·4 % in EIA.ConclusionsExcessive iodine intake may lead to increased prevalence of biochemical thyroid dysfunction, especially biochemical hypothyroidism. This is not related to an increase in prevalence of thyroid antibodies. Women are more susceptible to iodine excess.

scholarly journals Drinking water contributes to excessive iodine intake among children in Hebei, China

2013 ◽  
Vol 67 (9) ◽  
pp. 961-965 ◽  
Author(s):  
S Lv ◽  
Y Wang ◽  
D Xu ◽  
S Rutherford ◽  
Z Chong ◽  
...  
Keyword(s):  
Drinking Water ◽  
Iodine Intake ◽  
Excessive Iodine ◽  
Excessive Iodine Intake

scholarly journals An epidemiological survey of children's iodine nutrition and goitre status in regions with mildly excessive iodine in drinking water in Hebei Province, China

2012 ◽  
Vol 15 (7) ◽  
pp. 1168-1173 ◽  
Author(s):  
Shengmin Lv ◽  
Jun Zhao ◽  
Dong Xu ◽  
Zhengshui Chong ◽  
Lihui Jia ◽  
...  
Keyword(s):  
Drinking Water ◽  
Urinary Iodine ◽  
Thyroid Volume ◽  
Iodine Concentration ◽  
Hebei Province ◽  
Systematic Sampling ◽  
Urinary Iodine Concentration ◽  
Iodine Nutrition ◽  
Excessive Iodine ◽  
Salt Iodine

AbstractObjectiveTo identify children's iodine nutrition and goitre status in areas with mildly excessive iodine in drinking water.DesignA cross-sectional survey. Probability proportional to size sampling was employed to randomly select children from thirty townships where the median iodine content in drinking water ranged from 150 to 300 μg/l; their urinary iodine concentrations were determined and their thyroid volumes were measured by ultrasound. Drinking water samples and salt samples from the villages where the children lived were collected using a systematic sampling method.SettingHebei Province of China.SubjectsA total of 1259 children aged 8–10 years (621 boys and 638 girls).ResultsChildren's median urinary iodine concentration was found to be 418·8 μg/l, and the iodine concentration was >300 μg/l for 68·3 % (248/363) of the urine samples. Children's median urinary iodine concentration in villages with median salt iodine >10 mg/kg was significantly higher than that in villages with median salt iodine <5 mg/kg (442·9 μg/l v. 305·4 μg/l, P ≈ 0). The goitre rate of 1259 children examined by ultrasound was 10·96 %.ConclusionsThe iodine intake of children living in areas with mildly excessive iodine in drinking water in Hebei Province was found to be excessive. The measured iodine excess in the sampled children is exacerbated by consumption of iodized salt. Goitre was identified in these areas; however, due to the limitation of the current criteria for children's thyroid volume, a comprehensive assessment of the prevalence of goitre in these regions could not be made and further study is required.

Neonatal thyroid function born to mothers living with long-term excessive iodine intake from drinking water

2014 ◽  
Vol 83 (3) ◽  
pp. 399-404 ◽  
Author(s):  
Wen Chen ◽  
Zhongna Sang ◽  
Long Tan ◽  
Shufen Zhang ◽  
Feng Dong ◽  
...  
Keyword(s):  
Drinking Water ◽  
Thyroid Function ◽  
Iodine Intake ◽  
Excessive Iodine ◽  
Neonatal Thyroid Function ◽  
Excessive Iodine Intake

scholarly journals The prevalence of thyroid dysfunction in elderly cardiology patients with mild excessive iodine intake in the urban area of São Paulo

Clinics ◽  
2009 ◽  
Vol 64 (2) ◽  
pp. 135-142 ◽  
Author(s):  
Glaucia C. Duarte ◽  
Eduardo K. Tomimori ◽  
Rosalinda Y. A. Camargo ◽  
Ileana G.S. Rubio ◽  
Mauricio Wajngarten ◽  
...  
Keyword(s):  
Urban Area ◽  
Thyroid Dysfunction ◽  
Iodine Intake ◽  
Sao Paulo ◽  
São Paulo ◽  
Excessive Iodine ◽  
Excessive Iodine Intake

Excessive iodine intake and thyroid dysfunction among lactating Saharawi women

2015 ◽  
Vol 31 ◽  
pp. 279-284 ◽  
Author(s):  
Inger Aakre ◽  
Trine Bjøro ◽  
Ingrid Norheim ◽  
Tor A. Strand ◽  
Ingrid Barikmo ◽  
...  
Keyword(s):  
Thyroid Dysfunction ◽  
Iodine Intake ◽  
Excessive Iodine ◽  
Excessive Iodine Intake

scholarly journals Thyroid Dysfunction during Late Gestation Is Associated with Excessive Iodine Intake in Pregnant Women

2012 ◽  
Vol 97 (8) ◽  
pp. E1363-E1369 ◽  
Author(s):  
ZhongNa Sang ◽  
Wei Wei ◽  
Na Zhao ◽  
GuiQin Zhang ◽  
Wen Chen ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Thyroid Dysfunction ◽  
Iodine Intake ◽  
Late Gestation ◽  
Excessive Iodine ◽  
Excessive Iodine Intake

scholarly journals Establishment of an iodine model for prevention of iodine-excess-induced thyroid dysfunction in pregnant women

2021 ◽  
Vol 16 (1) ◽  
pp. 1357-1364
Author(s):  
Yuhan Zhou ◽  
Fen Chen ◽  
Lingyu Wang ◽  
Chunhui Tian ◽  
Shuo Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Regression Model ◽  
Pregnant Women ◽  
Thyroid Dysfunction ◽  
Logistic Regression Model ◽  
Iodine Intake ◽  
Iodine Excess ◽  
Excessive Iodine ◽  
Excessive Iodine Intake

Abstract This study aims to explore the relationship between the iodine status and thyroid dysfunction (TD) in pregnant women and establish a model to guide them to prevent excessive iodine intake. A total of 515 pregnant women were enrolled in the study. Urinary iodine concentration (UIC), thyroid hormones, and thyroid autoantibodies were measured, and then a logistic regression model was established. The median UIC of pregnant women was 174 ± 120 μg/L. Multivariate logistic regression analysis indicated that multivitamin supplements containing iodine and frequent seafood consumption were risk factors for excessive iodine (UIC ≥500 μg/L). Besides, excessive iodine was a risk factor for TD. Iodine excess was associated with a high prevalence of TD in pregnant women, especially TPOAb-positive women (P < 0.05). A logistic regression model based on potential risk factors was established to predict the risk of excessive iodine intake among pregnant women and provide guidance to minimize the risk of excessive iodine intake, thus reducing the risk of TD.

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