Fast Hyperspectral Raman Imaging with Confocal Raman Microscopy at Optimized Spatial Resolution

2008 ◽  
Vol 14 (S2) ◽  
pp. 782-783
Author(s):  
M Kalbac ◽  
E Lee ◽  
A Zoubir ◽  
A Whitley

Extended abstract of a paper presented at Microscopy and Microanalysis 2008 in Albuquerque, New Mexico, USA, August 3 – August 7, 2008

2018 ◽  
Vol 91 (1) ◽  
pp. 1049-1055 ◽  
Author(s):  
Carol Korzeniewski ◽  
Jay P. Kitt ◽  
Saheed Bukola ◽  
Stephen E. Creager ◽  
Shelley D. Minteer ◽  
...  

2016 ◽  
Vol 24 (10) ◽  
pp. 10767 ◽  
Author(s):  
Han Cui ◽  
Weiqian Zhao ◽  
Yun Wang ◽  
Ying Fan ◽  
Lirong Qiu ◽  
...  

2017 ◽  
Vol 100 ◽  
pp. 119-128 ◽  
Author(s):  
M. Torres-Carrasco ◽  
A. del Campo ◽  
M.A. de la Rubia ◽  
E. Reyes ◽  
A. Moragues ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4222
Author(s):  
Richard Krombholz ◽  
Dominique Lunter

In the development of dermal drug formulations and cosmetics, understanding the penetration properties of the active ingredients is crucial. Given that widespread methods, including tape stripping, lack in spatial resolution, while being time- and labour-intensive, Confocal Raman Microscopy is a promising alternative. In optimizing topically applied formulations, or the development of generic formulations, comparative in-situ measurements have a huge potential of saving time and resources. In this work, we show our approach to in-situ skin penetration analysis by confocal Raman Microscopy. To analyse feasibility of the approach, we used caffeine solutions as model vehicles and tested the effectiveness of 1,2-pentanediol as a penetration enhancer for delivery to the skin.


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