Health-related quality of life of patients on antiretroviral treatment in Botswana: A cross-sectional study

2016 ◽  
Vol 15 (2) ◽  
pp. 214-222 ◽  
Author(s):  
Nnamdi O. Ndubuka ◽  
Hyun J. Lim ◽  
Valerie J. Ehlers ◽  
Dirk M. van der Wal

ABSTRACTObjective:Antiretroviral therapy (ART) affords longevity to patients infected with the human immune deficiency virus (HIV). Since little is known about the health-related quality of life (HRQoL) of persons who have been on ART for at least five years, the present study investigated the HRQoL of these patients in Botswana.Method:Medical records, structured interviews, and the World Health Organization Quality of Life–BREF (WHOQoL–HIV–BREF) instrument were employed to obtain information from 456 respondents.Results:Univariate and multivariate regression analyses showed that respondents' highest scores were in the “physical” domain (mean = 15.8, SD = 3.5), while the lowest scores were in the “environment” domain (mean = 12.9, SD = 2.5). Thus, the physical domain had the greatest impact on patients' overall HRQoL. Self-education about HIV-related issues was significantly correlated with all domains of HRQoL scores: physical (ρ = –2.32, CI95% = –3.02, –1.61); psychological (ρ = –2.26, CI95% = –2.87, –1.65); independence (ρ = –1.81, CI95% = –2.54, –1.06); social relationships (ρ = –1.40, CI95% = –2.13, –0.67); environment (ρ = –1.58, CI95% = –2.13, –1.04); and spirituality (ρ = –1.70, CI95% = –82.27, –1.13).Significance of results:HRQoL assessments can identify and address patients' needs, and it is important that guidelines be developed that will yield improved care to ART patients in Botswana.

2020 ◽  
Vol 27 (09) ◽  
pp. 1976-1982
Author(s):  
Subhan Ullah ◽  
Zubash Aslam ◽  
Ghulam Abbas Shiekh

Objectives: To determine the risk factors of depressive disorders and health related quality of life among adult patients of depression presenting at psychiatric OPD clinic of Aziz Fatima Hospital Faisalabad. Study Design: Cross-sectional study. Setting: Psychiatric OPD clinic of Aziz Fatima Hospital Faisalabad Pakistan. Period: 1st August 2019 to 31st December 2019. Material & Method: 150 patients for the screening of depression Patient Health Questionnaire (PHQ) was used. For measuring health related quality of life World Health Organization Quality of Life (WHOQOL-Brief) was used. Results: It was found that out of 150 patients with depressive disorder 104(69.3%) were female and 46(30.7%) were male patients. Findings of the study assessed that depressive disorder not only impacts on the patients' mood but it also impairs the individuals overall perception of their general health, physical health, psychological wellbeing, social relationship and also distorted perception of their surrounding psychosocial environment. Conclusion: Depressive disorder is common in patients visiting psychiatric OPD clinic and findings of study suggested that age, education level, socio-economic status, death of parent at early age, unemployment, workplace issues, parental separation, loss of partner and family history of depression are important demographic variables which plays the role of significant risk factor for depression and impairs the quality of life among depressive patients.


2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Abílio Reis ◽  
Mário Santos ◽  
Margarida Vicente ◽  
Inês Furtado ◽  
Célia Cruz ◽  
...  

Background. Health-related quality of life (HRQoL) impairment is common in pulmonary hypertension (PH), but its clinical predictors are not well established. This study aims to characterize the HRQoL of patients with pulmonary arterial hypertension (PAH) and other precapillary forms of PH (pcPH) and to explore its clinical correlates. Materials and Methods. A cross-sectional, observational study of patients with documented PAH and other forms of pcPH. Patients completed two patient-reported outcome measures (PROM): Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) and Nottingham Health Profile (NHP). Clinical characteristics were retrieved from electronic medical records. Results. Mean CAMPHOR and NHP scores for the study population were indicative of a moderate HRQoL impairment. Patients in World Health Organisation Functional Classes (WHO FC) III/IV showed significantly worse HRQoL. The main clinical correlates of HRQoL were WHO FC, 6-minute walking distance (6MWD), and Borg dyspnoea index. Overall quality of life (QoL), assessed through CAMPHOR’s QoL domain, showed patterns comparable to HRQoL measured by both instruments. Conclusions. HRQoL, measured by two different PROMs, is impaired in Portuguese patients with PAH and other forms of pcPH, particularly in patients with increased disease severity. WHO FC, 6MWD, and Borg dyspnoea index are highly correlated with HRQoL and QoL.


Author(s):  
Funmilola Bosede Olutola ◽  
Grace A. Adejuwon

Background and Objective: Pregnancy and childbirth are periods of great joy and delicate, interesting, and exciting aspects of women’s life. The study investigates whether sleep quality components will predict health-related quality of life (HRQOL) domains among primigravidas. Materials and Methods: The study employed descriptive research design. 768 primigravidas, attending antenatal care in nine purposively-selected government hospitals in Ibadan, Nigeria, which fulfilled the inclusion criteria participated in the study. A questionnaire consisting of demographic information of primigravidas, World Health Organization Quality of Life-BREF (WHOQOL-BREF), and Pittsburgh Sleep Quality Index (PSQI) with reliability coefficient of 0.89 and 0.85, respectively, were used to collect data. Six hypotheses were tested using multiple regression analysis (MRA) and analysis of variance (ANOVA). Results: Sleep quality components had a statistical, joint influence on HRQOL domains (physical health domain, F = 4.526, P < 0.01; psychological domain, F = 2.931, P < 0.05; and environment domain, F = 2.788, P < 0.05) of primigravidas in Ibadan. In addition, domains of HRQOL were significantly influenced by primigravidas’ marital status (F = 3.591, P < 0.05). Conclusion: Effective management of sleep quality components during pregnancy can improve HRQOL domains of primigravidas. Researchers recommended that antenatal care lectures for primigravidas should be reinforced with emphasis on the sleep quality and its influence on their HRQOL domains for better wellness of the primigravidas.


Author(s):  
Jianjian Liu ◽  
Wei Yu ◽  
Jiayi Zhou ◽  
Yifan Yang ◽  
Shuoni Chen ◽  
...  

China has the largest population of older adults, most of whom suffer from one or more noncommunicable diseases (NCDs). The harm of the number of NCDs on the health-related quality of life (HRQOL) of older adults should be taken seriously. A sample of 5166 adults, aged 60 years and older, was included in this study. The Chinese version of the World Health Organization Quality of Life-Old (WHOQOL-OLD) instrument was used to assess the HRQOL. Multiple linear regression models were established to determine the relationship between the number of NCDs and the total score and scores of each dimension of the WHOQOL-OLD scale. After adjusting for confounding factors, suffering from one NCD (B = −0.87, 95% CI = −1.67 to −0.08, p < 0.05), two NCDs (B = −2.89, 95% CI = −3.87 to −1.90, p < 0.001), and three or more NCDs (B = −4.20, 95% CI = −5.36 to −3.05, p < 0.001), all had negative impacts on the HRQOL of older adults. NCDs had significant negative impacts on the HRQOL of older adults, and as the number of NCDs increased, the HRQOL of older adults deteriorated. Therefore, we should pay attention to the prevention and management of NCDs of older adults to prevent the occurrence of multiple NCDs.


2021 ◽  
Vol 23 (2) ◽  
Author(s):  
Zahra Ghiasi ◽  
Ali Alidadi ◽  
Abolfazl Payandeh ◽  
Afshin Emami ◽  
Shahab Lotfinia

Background: Hemodialysis improves renal function and increases lifetime. However, it causes a fundamental change in the whole life of patients. Many of these patients express their fears of an unacceptable life. Objectives: This study aimed to evaluate the quality of life and death anxiety among patients on hemodialysis and determine their personality and demographic predictors. Methods: A total of 154 participants were recruited from the hemodialysis units of hospitals in Zahedan, the southeast of Iran. The participants completed the World Health Organization Quality of Life Brief Scale, Revised NEO Personality Inventory, and Templar's Death Anxiety Scale. Results: In this study, 60.4% of the patients had high levels of death anxiety. About 70% of the patients had low or moderate levels of quality of life. Conclusions: Personality is an essential factor in predicting health-related quality of life and death anxiety. This result provides a better understanding of the determinants of death anxiety and HQOL.


2019 ◽  
Vol 1 (2) ◽  
pp. 63-69

Introduction: Diabetes mellitus is a multifactorial disease caused by deficiency in insulin secretion, insulin action, or both. Poor quality of life contributes to decreased personal care, which in turn contributes to worsening glycemia control, enhanced risk of diabetic complications. This study aimed to determine the health-related quality of life (HRQOL) for diabetics as compared to gender-age matched control living in southern Gaza, Palestine. Methods: This study was a case-control. About 100 DM patients and age-sex matched 100 controls were randomly selected from the department of internal medicine at the Nasser Medical Complex in Khanyunis Governorate and the community. The World Health Organization Quality of Life Questionnaire – short version (WHOQOL-BREF) was used to evaluate the quality of life among the study population. Results: Those with diabetics, the HRQOL was significantly lesser than for controls in all domains with the largest differences in the environmental domains (difference of 5 points) and tinier differences in physical health, psychological health & social relationships (2, 3 and 3 points difference) (<0.001 for all). Low ratings in the field of social relations in both groups with tiny differences between them have been registered (3 points). Furthermore, there were no differences in mean of scores for all domains according to gender. Conclusion: The study population's total HRQOL (diabetics and controls) was poor. Health program must be developed to encourage improve dietary habits, healthier lifestyle, promote exercise, discourage smoking, avoid complications of diabetes and appropriately handle chronic diseases.


2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Nnamdi O. Ndubuka ◽  
Hyun J. Lim ◽  
Dirk M. Van der Wal ◽  
Valerie J. Ehlers

Background: Antiretroviral therapy (ART) improves patients’ health-related quality of life (HRQoL). Defaulting from ART has detrimental consequences, including the development of viral resistance, treatment failure and increased risks of disease progression. Little is known about the quality of life of ART defaulters and reasons for discontinuing their ART.Objectives: This study sought to measure the HRQoL of ART patients in Botswana who were on ART for up to 5 years but had discontinued treatment for at least 3 months, and to identify factors associated with ART defaulting.Method: We conducted a cross-sectional study with 104 eligible respondents in four ART clinics in south eastern Botswana. We assessed respondents’ HRQoL using the World Health Organization Quality of Life Questionnaire for HIV short form. Clinical information was obtained from respondents’ medical records. Data were analysed using SAS version 9.2.Results: Reasons for discontinuing ART were inaccessible clinics (22.4%), feeling better (21.4%), running out of pills (11.2%), depression (8.2%), lack of care and/or support (8.2%), failure to understand instructions (7.7%), medications’ side effects (6.1%) and alcohol abuse (3.1%). In multivariate analyses, respondents aged 36–45 years had a 0.03 lower independence HRQoL score compared to those aged 35 and younger (β = -0.03; 95% confidence interval: -1.72, -1.66). Despite defaulting from their ART, respondents’ calculated HRQoL scores wereConclusion: This study highlights the need to enhance ART adherence in order to improve the HRQoL of people living with HIV and/or AIDS.


2020 ◽  
Author(s):  
Shaojie Li ◽  
Yongtian Yin ◽  
Lijun Chen ◽  
Guanghui Cui ◽  
Jiaqin Li ◽  
...  

BACKGROUND Older adults’ health literacy levels are crucial to improving health outcomes and health-related quality of life (HRQoL). However, the impact of eHealth literacy on HRQoL in older adults is unclear. OBJECTIVE The aim of this study was to examine the association between eHealth literacy and HRQoL of older adults and provide reference for the development of network intervention measures related to the health quality of life of the older adults. METHODS An anonymous cross-sectional survey was conducted among 1,201 adults aged 60 or older from Jinan, China. The eHealth Literacy Scale and Short-Form Health Survey (SF-12) were used to measure eHealth literacy and HRQoL. We used linear regression to test the adjusted association between eHealth literacy and HRQoL. RESULTS Most participants (88.9%) had inadequate eHealth literacy. Lower eHealth literacy was related to older age ( F=12.618, P<.001), female gender( t=3.303, P<.01), living in rural areas( F=11.356, P<.001), having less education( F=59.084, P<.001), being unmarried, divorced or widowed( t=4.416, P<.001), having a lower family income( F=38.017, P<.001), living with others(χ2=4.319, P<.05), and not having health insurance( F=12.713, P<.001). There were significant differences across physical functioning( t=-4.862, P<.001), role- physical( t=-2.485, P<.05), bodily pain( t=-3.470, P<.01), general health( t=-4.449, P<.001), vitality( t=-3.498, P<.001), role-emotional( t=-2.654, P<.01), mental health( t=-4.150, P<.001), physical component summary( t=-6.350, P<.001) and mental component summary( t=-4.483, P<.001) between adequate eHealth literacy and inadequate eHealth literacy. After controlling for age, gender, and other covariates, adequate eHealth literacy was positively related to physical component summary ( beta=7.6, P<.001) and mental component summary(beta=4.6, P=.001). CONCLUSIONS This study showed that Chinese older adults with higher eHealth literacy were more likely to contribute to higher HRQoL. Thus, Older adults’ eHealth literacy levels need to be taken into account when formulating health education and promotion programs for older adults, especially when the expected outcome is to improve HRQoL.


2020 ◽  
Author(s):  
Yaqun Huang ◽  
Sha Yan ◽  
Hongfu Xie ◽  
Ben Wang ◽  
Zhixiang Zhao ◽  
...  

BACKGROUND Rosacea is a chronic inflammatory dermatosis with facial skin involved, leading to physical and emotional problems, which greatly affected quality of life (QoL) of patients. Dermatology Life Quality Index (DLQI) and willingness to pay (WTP) are well-established instruments assessing the health-related quality of life (HRQoL), while very few studies have been focused on this topic about rosacea in China. OBJECTIVE To investigate HRQoL in Chinese rosacea patients assessed by DLQI and WTP and investigate potential predictors for patients with HRQoL severely affected. METHODS This cross-sectional study was conducted on 973 patients with rosacea. Sociodemographic data, clinical features and DLQI were collected, and WTP was assessed by three standardized items. Multivariable logistic analysis was performed to investigate independent factors influencing QoL. RESULTS 921 questionnaires were accomplished by participants. The mean DLQI score was 11.6 (median 11). Patients were willing to pay an average of $1050.2 or € 896.2 (median $431.4 or € 368.1) for complete cure. 33.3% would like to pay more than 20% of their monthly income to achieve sustainable control. There were positive correlations between WTP with DLQI (P < .05). DLQI could be independently impacted by age (21-30 and 31-40, OR = 3.242 and 3.617, respectively), the occupational requirement of appearance (high, OR = 4.410), disease duration (< 2 years, OR = 1.582), oedema (OR = 1.844) and severity of flushing, burning, stinging and pruritus (severe, OR = 2.003, 1.981, 2.491, 2.249, respectively). There were no significant associations between WTP and most of the clinical factors. CONCLUSIONS The QoL was negatively affected and should not be ignored among rosacea patients in China. Patients aged 21-40y, having occupational requirement of appearance, with the disease duration less than 2 years, and suffering severe flushing and related symptoms were more likely to have severe or very severe limitation of QoL.


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