scholarly journals FRIENDSHIP IS SKIN (COLOR) DEEP

2021 ◽  
pp. 1-27
Author(s):  
Emilce Santana
Keyword(s):  
Skin Color ◽  
Large Body ◽  
Longitudinal Survey ◽  
Logit Models ◽  
Limited Evidence ◽  
Status Group ◽  
Multinomial Logit Models ◽  
Close Friendships ◽  
Lower Status

Abstract Friendships between members of different ethnoracial groups can help to reduce prejudice and ease tensions across ethnoracial groups. A large body of literature has explored possible determinants for the formation of these friendships. One unexplored factor is the role of an individual’s skin color in influencing their opportunities to befriend members of other ethnoracial groups. This study seeks to answer two questions: For ethnoracial minorities, how is an individual’s skin color associated with the likelihood that they will engage in a cross-ethnoracial friendship? Does the role of skin color depend on the ethnoracial combination of the two groups that befriend one another? Using waves 1, 2, and 3 of the National Longitudinal Survey of Freshmen and a series of multinomial logit models, the results suggest that the role of skin color is a function of the relative levels of social status of the two ethnoracial groups that befriend one another. I argue that lighter-skinned members of lower status ethnoracial groups have a greater likelihood of having close friendships with members of higher status ethnoracial groups. There is also limited evidence that darker-skinned members of a higher status group, specifically Asians, have a greater likelihood of having close friends from a lower status group.

scholarly journals The MAL Protein, an Integral Component of Specialized Membranes, in Normal Cells and Cancer

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1065
Author(s):  
Armando Rubio-Ramos ◽  
Leticia Labat-de-Hoz ◽  
Isabel Correas ◽  
Miguel A. Alonso
Keyword(s):  
Epithelial Cells ◽  
Large Body ◽  
Original Description ◽  
Cell Types ◽  
Future Research ◽  
Transmembrane Segments ◽  
Epsilon Toxin ◽  
Proteolipid Proteins ◽  
Polarized Epithelial Cells

The MAL gene encodes a 17-kDa protein containing four putative transmembrane segments whose expression is restricted to human T cells, polarized epithelial cells and myelin-forming cells. The MAL protein has two unusual biochemical features. First, it has lipid-like properties that qualify it as a member of the group of proteolipid proteins. Second, it partitions selectively into detergent-insoluble membranes, which are known to be enriched in condensed cell membranes, consistent with MAL being distributed in highly ordered membranes in the cell. Since its original description more than thirty years ago, a large body of evidence has accumulated supporting a role of MAL in specialized membranes in all the cell types in which it is expressed. Here, we review the structure, expression and biochemical characteristics of MAL, and discuss the association of MAL with raft membranes and the function of MAL in polarized epithelial cells, T lymphocytes, and myelin-forming cells. The evidence that MAL is a putative receptor of the epsilon toxin of Clostridium perfringens, the expression of MAL in lymphomas, the hypermethylation of the MAL gene and subsequent loss of MAL expression in carcinomas are also presented. We propose a model of MAL as the organizer of specialized condensed membranes to make them functional, discuss the role of MAL as a tumor suppressor in carcinomas, consider its potential use as a cancer biomarker, and summarize the directions for future research.

scholarly journals In the Ear of the Listener: The Role of Foreign Accent in Interethnic Friendships and Partnerships

2021 ◽  
pp. 019791832098883
Author(s):  
Irena Kogan ◽  
Jörg Dollmann ◽  
Markus Weißmann
Keyword(s):  
Social Interactions ◽  
Social Distance ◽  
Children Of Immigrants ◽  
Longitudinal Survey ◽  
Foreign Accent ◽  
Interethnic Relations ◽  
Accented Speech ◽  
Interethnic Friendships ◽  
Communicative Power

This article examines the association between accented speech and the formation of friendships and partnerships among immigrants and native-born majority residents in Germany. Drawing on the sixth wave of the German extension of the Children of Immigrants Longitudinal Survey in Four European Countries, we analyze a neglected aspect of language — pronunciation — and find that speaking with a foreign accent is a more important correlate of the incidence of interethnic partnerships than of interethnic friendships. We argue that beyond its primary function of understandability, accented speech possesses socially communicative power. Accent transmits signals of an individual’s foreignness and cultural differences and, thus, becomes an additional marker of social distance. Such signals serve as a greater obstacle to more consequential intimate interethnic relations such as partnerships. Our findings extend the scholarly debate on the role of symbolic boundaries in social interactions between ethnic groups by yet another important boundary maker — accent.

scholarly journals Role of Matrix Gla Protein in the Complex Network of Coronary Artery Disease: A Comprehensive Review

Life ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 737
Author(s):  
Marko Kumric ◽  
Josip A. Borovac ◽  
Tina Ticinovic Kurir ◽  
Dinko Martinovic ◽  
Ivan Frka Separovic ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Complex Network ◽  
Vascular Calcification ◽  
Vitamin K ◽  
Clinical Decision Making ◽  
Large Body ◽  
Matrix Gla Protein ◽  
Artery Disease

Coronary artery disease (CAD) is widely recognized as one of the most important clinical entities. In recent years, a large body of accumulated data suggest that coronary artery calcification, a process highly prevalent in patients with CAD, occurs via well-organized biologic processes, rather than passively, as previously regarded. Matrix Gla protein (MGP), a vitamin K-dependent protein, emerged as an important inhibitor of both intimal and medial vascular calcification. The functionality of MGP hinges on two post-translational modifications: phosphorylation and carboxylation. Depending on the above-noted modifications, various species of MGP may exist in circulation, each with their respective level of functionality. Emerging data suggest that dysfunctional species of MGP, markedly, dephosphorylated-uncarboxylated MGP, might find its application as biomarkers of microvascular health, and assist in clinical decision making with regard to initiation of vitamin K supplementation. Hence, in this review we summarized the current knowledge with respect to the role of MGP in the complex network of vascular calcification with concurrent inferences to CAD. In addition, we discussed the effects of warfarin use on MGP functionality, with concomitant implications to coronary plaque stability.

scholarly journals Studying Collaboration Dynamics in Physical Learning Spaces: Considering the Temporal Perspective through Epistemic Network Analysis

Sensors ◽  
2021 ◽  
Vol 21 (9) ◽  
pp. 2898
Author(s):  
Milica Vujovic ◽  
Ishari Amarasinghe ◽  
Davinia Hernández-Leo
Keyword(s):  
Collaborative Learning ◽  
Temporal Analysis ◽  
Learning Design ◽  
Learning Spaces ◽  
Limited Evidence ◽  
Temporal Perspective ◽  
Learning Space ◽  
Collaboration Dynamics ◽  
Collaborative Activities

The role of the learning space is especially relevant in the application of active pedagogies, for example those involving collaborative activities. However, there is limited evidence informing learning design on the potential effects of collaborative learning spaces. In particular, there is a lack of studies generating evidence derived from temporal analyses of the influence of learning spaces on the collaborative learning process. The temporal analysis perspective has been shown to be essential in the analysis of collaboration processes, as it reveals the relationships between students’ actions. The aim of this study is to explore the potential of a temporal perspective to broaden understanding of the effects of table shape on collaboration when different group sizes and genders are considered. On-task actions such as explanation, discussion, non-verbal interaction, and interaction with physical artefacts were observed while students were engaged in engineering design tasks. Results suggest that table shape influences student behaviour when taking into account different group sizes and different genders.

Limited evidence for the role of environmental factors in the unusual peak of influenza in Brisbane during the 2018–2019 Australian summer

2021 ◽  
Vol 776 ◽  
pp. 145967
Author(s):  
Jianyun Lu ◽  
Zhicong Yang ◽  
Anjana C. Karawita ◽  
Myrna Bunte ◽  
Keng Yih Chew ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Limited Evidence ◽  
Australian Summer

scholarly journals Where to go to in chlamydia control? From infection control towards infectious disease control

2021 ◽  
pp. sextrans-2021-054992
Author(s):  
Jan E A M van Bergen ◽  
Bernice Maria Hoenderboom ◽  
Silke David ◽  
Febe Deug ◽  
Janneke C M Heijne ◽  
...  
Keyword(s):  
Chlamydia Infection ◽  
Limited Evidence ◽  
Future Directions ◽  
Tubal Factor Infertility ◽  
Effectiveness Analysis ◽  
Population Prevalence ◽  
Tubal Factor ◽  
Health Relevance ◽  
Asymptomatic Infections

ObjectivesThe clinical and public health relevance of widespread case finding by testing for asymptomatic chlamydia infections is under debate. We wanted to explore future directions for chlamydia control and generate insights that might guide for evidence-based strategies. In particular, we wanted to know the extent to which we should pursue testing for asymptomatic infections at both genital and extragenital sites.MethodsWe synthesised findings from published literature and from discussions among national and international chlamydia experts during an invitational workshop. We described changing perceptions in chlamydia control to inform the development of recommendations for future avenues for chlamydia control in the Netherlands.ResultsDespite implementing a range of interventions to control chlamydia, there is no practice-based evidence that population prevalence can be reduced by screening programmes or widespread opportunistic testing. There is limited evidence about the beneficial effect of testing on pelvic inflammatory disease prevention. The risk of tubal factor infertility resulting from chlamydia infection is low and evidence on the preventable fraction remains uncertain. Overdiagnosis and overtreatment with antibiotics for self-limiting and non-viable infections have contributed to antimicrobial resistance in other pathogens and may affect oral, anal and genital microbiota. These changing insights could affect the outcome of previous cost–effectiveness analysis.ConclusionThe balance between benefits and harms of widespread testing to detect asymptomatic chlamydia infections is changing. The opinion of our expert group deviates from the existing paradigm of ‘test and treat’ and suggests that future strategies should reduce, rather than expand, the role of widespread testing for asymptomatic chlamydia infections.

scholarly journals Role of interferon gamma release assay in the diagnosis and management of Mycobacterium tuberculosis-associated uveitis: a review

2021 ◽  
Vol 6 (1) ◽  
pp. e000663
Author(s):  
Samra Rahman ◽  
Muhammad Irfan ◽  
M A Rehman Siddiqui
Keyword(s):  
Interferon Gamma ◽  
Interferon Gamma Release Assay ◽  
Limited Evidence ◽  
Ocular Tuberculosis ◽  
Diagnosis And Management ◽  
Pubmed Database ◽  
Interferon Gamma Release Assays ◽  
Infectious Uveitis ◽  
Release Assay

Tuberculosis (TB)-associated uveitis is a common cause of infectious uveitis in the developing world. Diagnosis of TB uveitis remains a challenge. The role of interferon gamma release assays (IGRAs) is uncertain. Herein we summarise the available literature on the utility of IGRAs in the diagnosis and management of TB uveitis. We searched PubMed database from 1 August 2010 to 31 July 2020 using the following keywords alone and in combination: ‘interferon-gamma release assay’, ‘QuantiFERON’, ‘T-SPOT.TB’, ‘TB uveitis’, ‘serpiginous like choroiditis’, ‘tuberculoma’, ‘TB vasculitis’, ‘TB panuveitis’ and ‘ocular tuberculosis’. Data from 58 relevant studies were collated. The review is focused on currently marketed versions of IGRA tests: QuantiFERON-TB Gold In-Tube assay, QuantiFERON-TB Gold Plus assay (QFT-Plus) and T-SPOT.TB. We found limited evidence regarding the diagnostic utility of IGRA in patients with uveitis. No study was identified evaluating the newer QFT test—the QFT-Plus—in patients with uveitis. Similarly, there is lack of data directly comparing QFT-Plus with T-SPOT.TB specifically for the diagnosis of TB uveitis.

scholarly journals Can SMS Technology Improve Low Take-up of Social Benefits?

2014 ◽  
Vol 20 (1) ◽  
pp. 61-81 ◽  
Author(s):  
Mariana Blanco ◽  
Juan F. Vargas
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Well Being ◽  
Social Benefits ◽  
Limited Evidence ◽  
Randomized Controlled ◽  
Potential Channels ◽  
Informational Barriers ◽  
Government Benefits

AbstractLow take-up of stigma-free social benefits is often blamed on information asymmetries or administrative barriers. There is limited evidence on which of these potential channels is more salient in which contexts. We designed and implemented a randomized controlled trial to assess the extent to which informational barriers are responsible for the prevalent low take-up of government benefits among Colombian conflict-driven internal refugees. We provide timely information on benefits eligibility via SMS to a random half of the displaced household that migrated to Bogotá over a 6-month period. We show that improving information increases benefits’ take-up. However, the effect is small and only true for certain type of benefits. Hence, consistent with previous experimental literature, the availability of timely information explains only part of the low take-up rates and the role of administrative barriers and bureaucratic processes should be tackled to increase the well-being of internal refugees in Colombia.

Sign in / Sign up

Export Citation Format

Share Document