Addition–Elimination Mechanism-Activated Nucleotide Transition Sequencing for RNA Dynamics Profiling

Author(s):  
Li Su ◽  
Feng Chen ◽  
Huahang Yu ◽  
Hao Yan ◽  
Fengjiao Zhao ◽  
...  
Science ◽  
2021 ◽  
Vol 372 (6547) ◽  
pp. 1162.11-1164
Author(s):  
Di Jiang
Keyword(s):  

2017 ◽  
Vol 129 (43) ◽  
pp. 13664-13668 ◽  
Author(s):  
Christian Riml ◽  
Thomas Amort ◽  
Dietmar Rieder ◽  
Catherina Gasser ◽  
Alexandra Lusser ◽  
...  
Keyword(s):  

1992 ◽  
Vol 263 (3) ◽  
pp. R647-R652 ◽  
Author(s):  
O. Vuolteenaho ◽  
P. Koistinen ◽  
V. Martikkala ◽  
T. Takala ◽  
J. Leppaluoto

To evaluate the role of atrial natriuretic peptide (ANP) in exercise-related cardiovascular and hormonal adjustments in hypobaric conditions, 14 young athletes performed a maximal ergometer test in a hypobaric chamber adjusted to simulate the altitudes of sea level and 3,000 m. Plasma immunoreactive ANP levels rose from 5.89 to 35.1 pmol/l at sea level and rose significantly less (P less than 0.05), from 5.36 to 22.3 pmol/l, at simulated 3,000 m. Plasma immunoreactive amino-terminal peptide of proANP (NT-proANP) levels increased to the same extent at sea level and at simulated 3,000 m (from 240 to 481 pmol/l and from 257 to 539 pmol/l, respectively). Plasma immunoreactive aldosterone increased significantly less at simulated 3,000 m (P less than 0.05), but the changes in plasma renin were similar in both conditions. Plasma immunoreactive endothelin-1 and serum erythropoietin levels remained unchanged. In conclusion, we found a blunted ANP response to maximal exercise of ANP in acute hypobaric exposure compared with that in normobaric conditions, but no significant difference in the NT-proANP responses between the two conditions. The divergence may be due to stimulation of the elimination mechanism of ANP.


2017 ◽  
Vol 121 (37) ◽  
pp. 8626-8637 ◽  
Author(s):  
Alberto M. dos Santos ◽  
Anderson H. Lima ◽  
Cláudio Nahum Alves ◽  
Jerônimo Lameira

2017 ◽  
Vol 4 (1) ◽  
pp. 95-110 ◽  
Author(s):  
Deepika Punj ◽  
Ashutosh Dixit

In order to manage the vast information available on web, crawler plays a significant role. The working of crawler should be optimized to get maximum and unique information from the World Wide Web. In this paper, architecture of migrating crawler is proposed which is based on URL ordering, URL scheduling and document redundancy elimination mechanism. The proposed ordering technique is based on URL structure, which plays a crucial role in utilizing the web efficiently. Scheduling ensures that URLs should go to optimum agent for downloading. To ensure this, characteristics of both agents and URLs are taken into consideration for scheduling. Duplicate documents are also removed to make the database unique. To reduce matching time, document matching is made on the basis of their Meta information only. The agents of proposed migrating crawler work more efficiently than traditional single crawler by providing ordering and scheduling of URLs.


2008 ◽  
Vol 283 (50) ◽  
pp. 34785-34795 ◽  
Author(s):  
Heather C. Stuart ◽  
Zongjian Jia ◽  
Anat Messenberg ◽  
Bharat Joshi ◽  
T. Michael Underhill ◽  
...  

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