Streamlined Characterization of an Antibody–Drug Conjugate by Two-Dimensional and Four-Dimensional Liquid Chromatography/Mass Spectrometry

Antibody Drug Conjugate ◽

Drug Conjugate ◽

Antibody Drug

Multiple heart-cutting and comprehensive two-dimensional liquid chromatography hyphenated to mass spectrometry for the characterization of the antibody-drug conjugate ado-trastuzumab emtansine

Journal of Chromatography B ◽

10.1016/j.jchromb.2016.04.040 ◽

2016 ◽

Vol 1032 ◽

pp. 119-130 ◽

Cited By ~ 28

Author(s):

Koen Sandra ◽

Gerd Vanhoenacker ◽

Isabel Vandenheede ◽

Mieke Steenbeke ◽

Maureen Joseph ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Trastuzumab Emtansine ◽

Two Dimensional ◽

Antibody Drug Conjugate ◽

Drug Conjugate ◽

Antibody Drug

A rapid approach for characterization of thiol-conjugated antibody–drug conjugates and calculation of drug–antibody ratio by liquid chromatography mass spectrometry

10.1016/j.ab.2015.06.001 ◽

2015 ◽

Vol 485 ◽

pp. 34-42 ◽

Cited By ~ 30

Author(s):

David Firth ◽

Leonard Bell ◽

Martin Squires ◽

Sian Estdale ◽

Colin McKee

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Antibody Drug Conjugates ◽

Drug Conjugates ◽

Drug Antibody Ratio ◽

Antibody Ratio ◽

Antibody Drug

Two-dimensional liquid chromatography-mass spectrometry for the characterization of modified oligonucleotide impurities

10.1016/j.ab.2018.06.019 ◽

2018 ◽

Vol 556 ◽

pp. 45-52 ◽

Cited By ~ 9

Author(s):

Stilianos G. Roussis ◽

Isaiah Cedillo ◽

Claus Rentel

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Two Dimensional ◽

Modified Oligonucleotide

Enrichment and characterization of histones by two-dimensional hydroxyapatite/reversed-phase liquid chromatography–mass spectrometry

10.1016/j.ab.2009.01.033 ◽

2009 ◽

Vol 388 (1) ◽

pp. 47-55 ◽

Cited By ~ 8

Author(s):

Xiaodan Su ◽

Naduparambil K. Jacob ◽

Ravindra Amunugama ◽

Pang-Hung Hsu ◽

Richard Fishel ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Reversed Phase ◽

Two Dimensional ◽

Reversed Phase Liquid Chromatography ◽

Phase Liquid

On-line characterization of monoclonal antibody variants by liquid chromatography–mass spectrometry operating in a two-dimensional format

10.1016/j.ab.2011.07.033 ◽

2011 ◽

Vol 419 (1) ◽

pp. 17-25 ◽

Cited By ~ 55

Author(s):

Melissa Alvarez ◽

Guillaume Tremintin ◽

Jennifer Wang ◽

Marian Eng ◽

Yung-Hsiang Kao ◽

...

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibody ◽

Liquid Chromatography ◽

Two Dimensional ◽

On Line

Faculty Opinions recommendation of Investigating the in vitro metabolism of fipexide: characterization of reactive metabolites using liquid chromatography/mass spectrometry.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1088147.541144 ◽

2007 ◽

Author(s):

Gary Rankin

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

In Vitro Metabolism ◽

Reactive Metabolites ◽

Chromatography Mass Spectrometry

Characterization of theMycobacterium tuberculosisProteome by Liquid Chromatography Mass Spectrometry-based Proteomics Techniques: A Comprehensive Resource for Tuberculosis Research

Journal of Proteome Research ◽

10.1021/pr2007939 ◽

2011 ◽

Vol 11 (1) ◽

pp. 119-130 ◽

Cited By ~ 47

Author(s):

Christina Bell ◽

Geoffrey T. Smith ◽

Michael J. Sweredoski ◽

Sonja Hess

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Chromatography Mass Spectrometry

Two-dimensional liquid chromatography/mass spectrometry/mass spectrometry separation of water-soluble metabolites

Journal of Chromatography A ◽

10.1016/j.chroma.2010.10.068 ◽

2010 ◽

Vol 1217 (52) ◽

pp. 8161-8166 ◽

Cited By ~ 33

Author(s):

Jacob N. Fairchild ◽

Krisztian Horvath ◽

Jessica R. Gooding ◽

Shawn R. Campagna ◽

Georges Guiochon

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Water Soluble ◽

Two Dimensional ◽

Mass Spectrometry Mass Spectrometry

Characterization of Groundwater Samples from Superfund Sites by Gas Chromatography/Mass Spectrometry and Liquid Chromatography/Mass Spectrometry

Environmental Science & Technology ◽

10.1021/es9602206 ◽

1996 ◽

Vol 30 (12) ◽

pp. 3558-3564 ◽

Cited By ~ 26

Author(s):

Leon D. Betowski ◽

Douglas S. Kendall ◽

Christopher M. Pace ◽

Joseph R. Donnelly

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Liquid Chromatography ◽

Gas Chromatography Mass Spectrometry ◽

Superfund Sites ◽

Groundwater Samples

Characterization of Phytoplankton Communities in Response to Macronutrient Treatments Determined by High-Performance Liquid Chromatography Mass Spectrometry

Analytical Letters ◽

10.1080/00032719.2015.1122029 ◽

2016 ◽

Vol 49 (11) ◽

pp. 1758-1771

Author(s):

Qijun Luo ◽

Yue Song ◽

Liyang Zheng ◽

Juanjuan Chen ◽

Jilin Xu ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

High Performance ◽

Phytoplankton Communities