Fluorescently Labeled Cyclodextrin Derivatives as Exogenous Markers for Real-Time Transcutaneous Measurement of Renal Function

2016 ◽  
Vol 27 (10) ◽  
pp. 2513-2526 ◽  
Author(s):  
Jiaguo Huang ◽  
Stefanie Weinfurter ◽  
Pedro Caetano Pinto ◽  
Marc Pretze ◽  
Bettina Kränzlin ◽  
...  
Keyword(s):  
Renal Function ◽  
Real Time ◽  
Cyclodextrin Derivatives ◽  
Transcutaneous Measurement

scholarly journals Reliability of Transcutaneous Measurement of Renal Function in Various Strains of Conscious Mice

PLoS ONE ◽  
2013 ◽  
Vol 8 (8) ◽  
pp. e71519 ◽  
Author(s):  
Daniel Schock-Kusch ◽  
Stefania Geraci ◽  
Esther Ermeling ◽  
Yury Shulhevich ◽  
Carsten Sticht ◽  
...  
Keyword(s):  
Renal Function ◽  
Transcutaneous Measurement

Real-Time Monitoring of Renal Function During Ischemic Injury in the Rhesus Monkey

Renal Failure ◽  
1995 ◽  
Vol 17 (5) ◽  
pp. 489-502 ◽  
Author(s):  
Craig E. Haug ◽  
Isaac A. Lopez ◽  
Richard H. Moore ◽  
Robert H. Rubin ◽  
Nina Tolkoff-Rubin ◽  
...  
Keyword(s):  
Renal Function ◽  
Rhesus Monkey ◽  
Real Time ◽  
Ischemic Injury ◽  
Real Time Monitoring

scholarly journals Real-time urinary electrolyte monitoring after furosemide administration in surgical ICU patients with normal renal function

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Luca Zazzeron ◽  
Davide Ottolina ◽  
Eleonora Scotti ◽  
Michele Ferrari ◽  
Paola Bruzzone ◽  
...  
Keyword(s):  
Renal Function ◽  
Real Time ◽  
Normal Renal Function ◽  
Icu Patients ◽  
Surgical Icu ◽  
Furosemide Administration

Real-time point-of-care measurement of impaired renal function in a rat acute injury model employing exogenous fluorescent tracer agents

2013 ◽  
Author(s):  
Richard B. Dorshow ◽  
Richard M. Fitch ◽  
Karen P. Galen ◽  
Jolette K. Wojdyla ◽  
Amruta R. Poreddy ◽  
...  
Keyword(s):  
Renal Function ◽  
Real Time ◽  
Impaired Renal Function ◽  
Point Of Care ◽  
Acute Injury ◽  
Fluorescent Tracer ◽  
Injury Model ◽  
Time Point

Transcutaneous measurement of renal function in conscious mice

2012 ◽  
Vol 303 (5) ◽  
pp. F783-F788 ◽  
Author(s):  
Andrea Schreiber ◽  
Yury Shulhevich ◽  
Stefania Geraci ◽  
Juergen Hesser ◽  
Dzmitry Stsepankou ◽  
...  
Keyword(s):  
Renal Function ◽  
Glomerular Filtration Rate ◽  
Filtration Rate ◽  
Plasma Clearance ◽  
Elimination Kinetics ◽  
Internal Memory ◽  
Freely Moving ◽  
Kinetics Of ◽  
Transcutaneous Measurement

Determination of glomerular filtration rate (GFR) in conscious mice is cumbersome for the experimenter and stressful for the animals. Here we report on a simple new technique allowing the transcutaneous measurement of GFR in conscious mice. This approach extends our previously developed technique for rats to mice. The technique relies on a miniaturized device equipped with an internal memory that permits the transcutaneous measurement of the elimination kinetics of the fluorescent renal marker FITC-sinistrin. This device is described and validated compared with FITC-sinistrin plasma clearance in healthy, unilaterally nephrectomized and pcy mice. In summary, we describe a technique allowing the measurement of renal function in freely moving mice independent of blood or urine sampling as well as of laboratory assays.

Development of fluorescent tracers for the real-time monitoring of renal function

2011 ◽  
Author(s):  
Amruta R. Poreddy ◽  
Bethel Asmelash ◽  
Martin P. Debreczeny ◽  
Richard M. Fitch ◽  
John N. Freskos ◽  
...  
Keyword(s):  
Renal Function ◽  
Real Time ◽  
Real Time Monitoring ◽  
Fluorescent Tracers ◽  
The Real
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