Determination of the Low Hg Accumulation in Rabbitfish (Siganus canaliculatus) by Various Elimination Pathways: Simulation by a Physiologically Based Pharmacokinetic Model

Environmental Science & Technology ◽

10.1021/acs.est.0c00772 ◽

2020 ◽

Vol 54 (12) ◽

pp. 7440-7449

Author(s):

Xun Wang ◽

Wen-Xiong Wang

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Siganus Canaliculatus ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Rabbitfish Siganus Canaliculatus ◽

Hg Accumulation

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Development of a Physiologically Based Pharmacokinetic Model for the Rat Central Nervous System and Determination of an In Vitro–In Vivo Scaling Methodology for the Blood–Brain Barrier Permeability of Two Transporter Substrates, Morphine and Oxycodone

Journal of Pharmaceutical Sciences ◽

10.1002/jps.23266 ◽

2012 ◽

Vol 101 (11) ◽

pp. 4277-4292 ◽

Author(s):

Kathryn Ball ◽

François Bouzom ◽

Jean-Michel Scherrmann ◽

Bernard Walther ◽

Xavier Declèves

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Brain Barrier Permeability ◽

Physiologically Based

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Physiologically based pharmacokinetic model development for trazodone: application to paediatric dose projection

10.26226/morressier.5971be87d462b80290b534f2 ◽

2017 ◽

Author(s):

F. Calisti

Keyword(s):

Pharmacokinetic Model ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Paediatric Dose

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Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime

Environmental Research ◽

10.1016/j.envres.2021.111287 ◽

2021 ◽

pp. 111287

Author(s):

Deepika Deepika ◽

Raju Prasad Sharma ◽

Marta Schuhmacher ◽

Vikas Kumar

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Perfluorooctane Sulfonate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

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Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthalate

Archives of Toxicology ◽

10.1007/s00204-021-03057-5 ◽

2021 ◽

Author(s):

Seung-Hyun Jeong ◽

Ji-Hun Jang ◽

Hea-Young Cho ◽

Yong-Bok Lee

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Major Metabolite ◽

Physiologically Based Pharmacokinetic Model ◽

Human Risk Assessment ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically‐Based Pharmacokinetic Model for Alectinib, Ruxolitinib, and Panobinostat in The Presence of Cancer, Renal Impairment, and Hepatic Impairment

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2282 ◽

2021 ◽

Author(s):

Mo'tasem M. Alsmadi

Keyword(s):

Renal Impairment ◽

Hepatic Impairment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Development of a Physiologically-Based Pharmacokinetic Model for Perchloroethylene Using Tissue Concentration-Time Data

Toxicology and Applied Pharmacology ◽

10.1006/taap.1994.1179 ◽

1994 ◽

Vol 128 (1) ◽

pp. 50-59 ◽

Author(s):

C.E. Dallas ◽

X.M. Chen ◽

K. Obarr ◽

S. Muralidhara ◽

P. Varkonyi ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Tissue Concentration ◽

Physiologically Based Pharmacokinetic Model ◽

Time Data ◽

Physiologically Based Pharmacokinetic ◽

Concentration Time ◽

Physiologically Based

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Development of a Physiologically Based Pharmacokinetic Model for Estradiol in Rats and Humans: A Biologically Motivated Quantitative Framework for Evaluating Responses to Estradiol and Other Endocrine-Active Compounds

Toxicological Sciences ◽

10.1093/toxsci/69.1.60 ◽

2002 ◽

Vol 69 (1) ◽

pp. 60-78 ◽

Author(s):

D. R. Plowchalk

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Active Compounds ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Analysis of the Disposition of a Novel p38 MAPK Inhibitor, AKP-001, and Its Metabolites in Rats with a Simple Physiologically Based Pharmacokinetic Model

Drug Metabolism and Disposition ◽

10.1124/dmd.114.060046 ◽

2014 ◽

Vol 43 (2) ◽

pp. 217-226 ◽

Author(s):

Kazuhiko Shirota ◽

Makoto Kaneko ◽

Makoto Sasaki ◽

Kouichi Minato ◽

Akira Fujikata ◽

...

Keyword(s):

P38 Mapk ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

P38 Mapk Inhibitor ◽

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Development and Application of a Multiroute Physiologically Based Pharmacokinetic Model for Oxytetracycline in Dogs and Humans

Journal of Pharmaceutical Sciences ◽

10.1002/jps.24244 ◽

2015 ◽

Vol 104 (1) ◽

pp. 233-243 ◽

Author(s):

Zhoumeng Lin ◽

Mengjie Li ◽

Ronette Gehring ◽

Jim E. Riviere

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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An Updated Physiologically Based Pharmacokinetic Model for Hexachlorobenzene: Incorporation of Pathophysiological States following Partial Hepatectomy and Hexachlorobenzene Treatment

Toxicological Sciences ◽

10.1093/toxsci/kfj133 ◽

2006 ◽

Vol 91 (1) ◽

pp. 29-41 ◽

Author(s):

Yasong Lu ◽

Manupat Lohitnavy ◽

Micaela B. Reddy ◽

Ornrat Lohitnavy ◽

Amanda Ashley ◽

...

Keyword(s):

Partial Hepatectomy ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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