Selective Inclusion of Secondary Amine Guests in sH Hydrate Systems

ABSTRACT A convenient and mild procedure is described in this paper whereby free and conjugated oestrogens may be extracted from urine. The extracts containing approximately 90 per cent of the oestrogens are devoid of most of the extraneous material and may be reduced in volume to less than 1/15 of that of the urine. The procedure consists of the following steps: (1) a 10 per cent (v/v) solution of a high molecular weight secondary amine (Amberlite LA-2, Rohm and Haas) in ethyl acetate is washed with formic acid and water, (2) the oestrogens in urine (acidified to pH 2 or 3 with H2SO4) are extracted with the LA-2 solution, (3) the oestrogen fraction is back-extracted from the organic solution with dilute aqueous ammonia.

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Regio-, Stereo- and Enantioselective α-Addition of Carbonyl Nucleo-philes to Allenamides Catalyzed by a Synergistic Copper/Enamine System

10.26434/chemrxiv.11830935.v1 ◽

2020 ◽

Author(s):

Rémi Blieck ◽

Sebastien Lemouzy ◽

Marc Taillefer ◽

Florian Monnier

Keyword(s):

Catalytic System ◽

Secondary Amine ◽

Primary Amine ◽

Synergistic Catalysis ◽

Enantioselective Addition ◽

Amine Catalysts

A dual copper/enamine catalytic system is found to enable an intermolecular enantioselective α-addition of various carbonyl nucleophiles to allenamides. Secondary amine catalysts allowed the highly enantioselective addition of aldehydes, while using primary amine catalysts led to the enantioselective addition of ketoester nucleophiles. The process was found to be highly regio-, stereo- and enantio-selective and represented the first allene hydrofunctionalization using an synergistic catalysis involving copper

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Faculty Opinions recommendation of Secondary amine selective Petasis (SASP) bioconjugation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.737461683.793571816 ◽

2020 ◽

Author(s):

Anna Mapp

Keyword(s):

Secondary Amine

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Synthesis of N4-Substituted Derivatives of 1-[2-(Phosphonomethoxy)ethyl]cytosine and Its Diisopropyl Ester as a Model Reaction for the Synthesis of N4-Substituted Derivatives of Cidofovir

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc20052066 ◽

2005 ◽

Vol 70 (12) ◽

pp. 2066-2074 ◽

Cited By ~ 3

Author(s):

Šárka Chalupová ◽

Antonín Holý ◽

Milena Masojídková

Keyword(s):

Secondary Amine ◽

Model Reaction ◽

Aqueous Methanol ◽

Derivatives Of ◽

Amine Salts

We have studied the reaction of 1-[2-(phosphonomethoxy)ethyl]cytosine (1) and its diisopropyl ester (2) with triethylammonium hydrogensulfite in 60% aqueous methanol. In the presence of some primary or secondary amine salts, at 25-70 °C, this reaction affords transaminated derivatives 4a-4e and 5a, 5b as main products accompanied by uracil compounds. However, with certain amines the reaction failed.

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Effect of the number of arms on the mechanical properties of a star-shaped cyclic olefin copolymer

Polymer Chemistry ◽

10.1039/c9py01186b ◽

2019 ◽

Vol 10 (41) ◽

pp. 5578-5583 ◽

Cited By ~ 1

Author(s):

Takumitsu Kida ◽

Ryo Tanaka ◽

Koh-hei Nitta ◽

Takeshi Shiono

Keyword(s):

Mechanical Properties ◽

Thermal Properties ◽

Physical Properties ◽

Secondary Amine ◽

Aggregation Number ◽

Drastic Change ◽

Cyclic Olefin Copolymer ◽

Cyclic Olefin

The increase of aggregation number in a star-shaped cyclic olefin copolymer was succeeded by using a triazine-based secondary amine, which caused a drastic change in physical properties without changing the thermal properties.

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Recent advances and prospects in the Zn-catalysed Mannich reaction

RSC Advances ◽

10.1039/d0ra10772g ◽

2021 ◽

Vol 11 (16) ◽

pp. 9098-9111

Author(s):

Salahudeen Shamna ◽

C. M. A. Afsina ◽

Rose Mary Philip ◽

Gopinathan Anilkumar

Keyword(s):

Carbonyl Compound ◽

Secondary Amine ◽

Mannich Reaction ◽

Mannich Base ◽

Mannich Reactions ◽

Recent Advances ◽

Primary Secondary Amine

Amino alkylation of an acidic α-proton of a carbonyl by formaldehyde and a primary/secondary amine or ammonia, affording a β-amino-carbonyl compound also known as a Mannich base is a valuable reaction. We focus on recent advances in Zn catalysed Mannich reactions.

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