Multi-Phase Solvation Model for Biological Membranes: Molecular Action Mechanism of Amphotericin B

2017 ◽  
Vol 13 (7) ◽  
pp. 3388-3397 ◽  
Author(s):  
J. M. Falcón-González ◽  
G. Jiménez-Domínguez ◽  
I. Ortega-Blake ◽  
M. Carrillo-Tripp
Keyword(s):  
Amphotericin B ◽  
Biological Membranes ◽  
Action Mechanism ◽  
Solvation Model ◽  
Molecular Action ◽  
Multi Phase

scholarly journals Molecular Action Mechanism of Amphotericin B and Structural Analogs on Biological Membranes

2010 ◽  
Vol 98 (3) ◽  
pp. 107a
Author(s):  
Mauricio Carrillo-Tripp ◽  
Alex H. de Vries ◽  
Rogelio Hernández ◽  
Cristina Vargas ◽  
Humberto Saint-Martin ◽  
...  
Keyword(s):  
Amphotericin B ◽  
Biological Membranes ◽  
Action Mechanism ◽  
Molecular Action

Molecular action mechanism of anti‐inflammatory hydrolysates obtained from brewers' spent grain

2020 ◽  
Vol 100 (7) ◽  
pp. 2880-2888
Author(s):  
Raúl E Cian ◽  
Cristina Hernández‐Chirlaque ◽  
Reyes Gámez‐Belmonte ◽  
Silvina R Drago ◽  
Fermín Sánchez de Medina ◽  
...  
Keyword(s):  
Action Mechanism ◽  
Molecular Action ◽  
Spent Grain ◽  
Anti Inflammatory

Fluorescence Studies on the Molecular Action of Amphotericin B on Susceptible and Resistant Fungal Cells†

Biochemistry ◽  
1996 ◽  
Vol 35 (24) ◽  
pp. 7983-7992 ◽  
Author(s):  
M. Page Haynes ◽  
Parkson Lee-Gau Chong ◽  
Helen R. Buckley ◽  
Ronald A. Pieringer
Keyword(s):  
Amphotericin B ◽  
Fluorescence Studies ◽  
Molecular Action

scholarly journals Study of the effect of some drugs used in the clinic on the AQP1 activity of the human erythrocyte membrane

2021 ◽  
Vol 18 (2) ◽  
pp. 204-211
Author(s):  
K. V. Basiakova ◽  
E. P. Titovets
Keyword(s):  
Erythrocyte Membrane ◽  
Water Exchange ◽  
Inhibitory Effect ◽  
Wide Distribution ◽  
Stopped Flow ◽  
Human Tissues ◽  
Human Erythrocyte Membrane ◽  
Action Mechanism ◽  
Molecular Action ◽  
Therapeutic Measures

Using the stopped flow method and based on the study of the intensity of light scattering, the effect of pharmacological preparations used in the clinic on the water exchange of human erythrocytes, catalyzed by aquaporin AQP1, was studied. Pharmacological preparations used in therapeutic concentrations have a variable inhibitory effect on water permeability of the erythrocyte membrane. The obtained results broaden our understanding of the molecular action mechanism of the investigated drugs. In view of the wide distribution of AQP1 in various human tissues, these data should be taken into account when carrying out therapeutic measures aimed at normalizing the water exchange of organs and tissues.

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