Substrate-Specific Inhibition Constants for Phospholipase A2 Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.8b01568 ◽

2019 ◽

Vol 62 (4) ◽

pp. 1999-2007 ◽

Author(s):

Varnavas D. Mouchlis ◽

Aaron Armando ◽

Edward A. Dennis

Keyword(s):

Phospholipase A2 ◽

Mixed Micelles ◽

Specific Inhibition ◽

Inhibition Constants

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Kinetic analysis of phospholipase A2 activity toward mixed micelles and its implications for the study of lipolytic enzymes

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)40687-x ◽

1975 ◽

Vol 250 (23) ◽

pp. 9013-9020 ◽

Author(s):

RA Deems ◽

BR Eaton ◽

EA Dennis

Keyword(s):

Phospholipase A2 ◽

Kinetic Analysis ◽

Mixed Micelles ◽

Lipolytic Enzymes ◽

Phospholipase A2 Activity

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Mechanism of Phospholipase A2 Action Toward Mixed Micelles of Detergent and Phospholipids

Advances in Experimental Medicine and Biology - Enzymes of Lipid Metabolism ◽

10.1007/978-1-4615-9071-2_15 ◽

1978 ◽

pp. 165-175 ◽

Author(s):

Edward A. Dennis

Keyword(s):

Phospholipase A2 ◽

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Kinetics of the Hydrolysis of Mixed Micelles of Dipalmitoyllecithin with Triton X-100 Catalyzed by a Phospholipase A2 from the Venom of Agkistrodon halys blomhoffii

The Journal of Biochemistry ◽

10.1093/oxfordjournals.jbchem.a123155 ◽

1990 ◽

Vol 108 (1) ◽

pp. 21-27 ◽

Author(s):

Keizo Teshima ◽

Yuji Samejima ◽

Saju Kawauchi ◽

Kiyoshi Ikeda

Keyword(s):

Phospholipase A2 ◽

Mixed Micelles ◽

Triton X ◽

Kinetics Of ◽

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Specific inhibition of Xenorhabdus hominickii, an entomopathogenic bacterium, against different types of host insect phospholipase A2

Journal of Invertebrate Pathology ◽

10.1016/j.jip.2017.08.009 ◽

2017 ◽

Vol 149 ◽

pp. 97-105 ◽

Author(s):

Md. Sadekuzzaman ◽

Yonggyun Kim

Keyword(s):

Phospholipase A2 ◽

Specific Inhibition ◽

Host Insect ◽

Different Types

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Analysis of human synovial fluid phospholipase A2 on short chain phosphatidylcholine-mixed micelles: Development of a spectrophotometric assay suitable for a microtiterplate reader

Analytical Biochemistry ◽

10.1016/0003-2697(92)90160-9 ◽

1992 ◽

Vol 204 (1) ◽

pp. 190-197 ◽

Author(s):

Laure J. Reynolds ◽

Lori L. Hughes ◽

Edward A. Dennis

Keyword(s):

Synovial Fluid ◽

Phospholipase A2 ◽

Mixed Micelles ◽

Spectrophotometric Assay ◽

Short Chain ◽

Human Synovial Fluid

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Sequence specific inhibition of human type II phospholipase A2, enzyme activity by phosphorothioate oligonucleotides

Nucleic Acids Research ◽

10.1093/nar/22.15.3202 ◽

1994 ◽

Vol 22 (15) ◽

pp. 3202-3209 ◽

Author(s):

C.Frank Bennett ◽

Ming-Yi Chiang ◽

Laura Wilson-Lingardo ◽

Jacqueline R. Wyatt

Keyword(s):

Enzyme Activity ◽

Phospholipase A2 ◽

Specific Inhibition ◽

Type Ii ◽

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First Structural Evidence of a Specific Inhibition of Phospholipase A2 by α-Tocopherol (Vitamin E) and its Implications in Inflammation: Crystal Structure of the Complex Formed Between Phospholipase A2 and α-Tocopherol at 1.8Å Resolution

Journal of Molecular Biology ◽

10.1016/s0022-2836(02)00473-4 ◽

2002 ◽

Vol 320 (2) ◽

pp. 215-222 ◽

Author(s):

Vikas Chandra ◽

Jayasankar Jasti ◽

Punit Kaur ◽

Ch. Betzel ◽

A. Srinivasan ◽

...

Keyword(s):

Crystal Structure ◽

Vitamin E ◽

Phospholipase A2 ◽

Specific Inhibition

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Interaction of enzymes with mixed micelles of phospholipid and detergent: Analysis of the phospholipase A2-dipalmitoyl phosphatidylcholine-triton X 100 system

Journal of Supramolecular Structure ◽

10.1002/jss.400020513 ◽

1974 ◽

Vol 2 (5-6) ◽

pp. 682-694 ◽

Author(s):

Edward A. Dennis

Keyword(s):

Phospholipase A2 ◽

Mixed Micelles ◽

Dipalmitoyl Phosphatidylcholine ◽

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Kinetic analysis of the competitive inhibition of phospholipase A2 in triton X-100 mixed micelles

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(00)80509-0 ◽

1992 ◽

Vol 2 (11) ◽

pp. 1343-1348 ◽

Author(s):

Yu Lin ◽

Edward A. Dennis

Keyword(s):

Phospholipase A2 ◽

Kinetic Analysis ◽

Mixed Micelles ◽

Competitive Inhibition ◽

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Pancreatic porcine phospholipase A2 catalyzed hydrolysis of phosphatidylcholine in lecithin-bile salt mixed micelles: Kinetic studies in a lecithin-sodium cholate system

Archives of Biochemistry and Biophysics ◽

10.1016/0003-9861(83)90155-8 ◽

1983 ◽

Vol 221 (2) ◽

pp. 361-370 ◽

Author(s):

William J. Hoffman ◽

Marianne Vahey ◽

Joseph Hajdu

Keyword(s):

Phospholipase A2 ◽

Bile Salt ◽

Mixed Micelles ◽

Kinetic Studies ◽

Sodium Cholate ◽

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