Anti-inflammatory and Quinone Reductase Inducing Compounds from Fermented Noni (Morinda citrifolia) Juice Exudates

2016 ◽  
Vol 79 (6) ◽  
pp. 1508-1513 ◽  
Author(s):  
Ui Joung Youn ◽  
Eun-Jung Park ◽  
Tamara P. Kondratyuk ◽  
Mayuramas Sang-Ngern ◽  
Marisa M. Wall ◽  
...  
Keyword(s):  
Quinone Reductase ◽  
Morinda Citrifolia ◽  
Anti Inflammatory

Anthraquinones with potent quinone reductase-inducing activity from the stem bark of Morinda citrifolia (Rubiaceae)

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
R Ho ◽  
O Ciclet ◽  
A Ben Zaied ◽  
P Raharivelomanana ◽  
M Cuendet
Keyword(s):  
Stem Bark ◽  
Quinone Reductase ◽  
Morinda Citrifolia

scholarly journals Morinda citrifolia(Noni) as an Anti-Inflammatory Treatment in Women with Primary Dysmenorrhoea: A Randomised Double-Blind Placebo-Controlled Trial

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
H. M. Fletcher ◽  
J. Dawkins ◽  
C. Rattray ◽  
G. Wharfe ◽  
M. Reid ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Morinda Citrifolia ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Menstrual Cycles ◽  
Primary Dysmenorrhoea ◽  
Before And After ◽  
Laboratory Variables ◽  
Anti Inflammatory ◽  
Bleeding Score

Introduction. Noni (Morinda citrifolia) has been used for many years as an anti-inflammatory agent. We tested the efficacy of Noni in women with dysmenorrhea.Method. We did a prospective randomized double-blind placebo-controlled trial in 100 university students of 18 years and older over three menstrual cycles. Patients were invited to participate and randomly assigned to receive 400 mg Noni capsules or placebo. They were assessed for baseline demographic variables such as age, parity, and BMI. They were also assessed before and after treatment, for pain, menstrual blood loss, and laboratory variables: ESR, hemoglobin, and packed cell volume.Results. Of the 1027 women screened, 100 eligible women were randomized. Of the women completing the study, 42 women were randomized to Noni and 38 to placebo. There were no significant differences in any of the variables at randomization. There were also no significant differences in mean bleeding score or pain score at randomization. Both bleeding and pain scores gradually improved in both groups as the women were observed over three menstrual cycles; however, the improvement was not significantly different in the Noni group when compared to the controls.Conclusion. Noni did not show a reduction in menstrual pain or bleeding when compared to placebo.

Pulmonary anti-inflammatory effects and spasmolytic properties of Costa Rican noni juice ( Morinda citrifolia L.)

2016 ◽  
Vol 192 ◽  
pp. 264-272 ◽  
Author(s):  
Emilie Dussossoy ◽  
Florence Bichon ◽  
Emilie Bony ◽  
Karine Portet ◽  
Pierre Brat ◽  
...  
Keyword(s):  
Costa Rican ◽  
Morinda Citrifolia ◽  
Anti Inflammatory

Characterization, anti-oxidative and anti-inflammatory effects of Costa Rican noni juice (Morinda citrifolia L.)

2011 ◽  
Vol 133 (1) ◽  
pp. 108-115 ◽  
Author(s):  
E. Dussossoy ◽  
P. Brat ◽  
E. Bony ◽  
F. Boudard ◽  
P. Poucheret ◽  
...  
Keyword(s):  
Costa Rican ◽  
Morinda Citrifolia ◽  
Anti Inflammatory

scholarly journals Efecto antiinflamatorio de extractos etanólicos de Morinda citrifolia L. en conejos

Tequio ◽  
2019 ◽  
Vol 2 (6) ◽  
pp. 26-34
Author(s):  
Irma Cecilia Regino Álvarez ◽  
María de la Luz Ríos Vásquez ◽  
Héctor Ulises Bernardino Hernández ◽  
Arturo Zapién Martínez
Keyword(s):  
Secondary Metabolites ◽  
Leaf Extract ◽  
Adverse Reactions ◽  
Morinda Citrifolia ◽  
San Jose ◽  
Mature Leaves ◽  
Therapeutic Properties ◽  
Anti Inflammatory ◽  
Ethanol Extracts ◽  
Inflammatory Effect

Morinda citrifolia L. has multiple therapeutic properties, particularly as an anti-inflammatory. The species has been widely studied, however, it is necessary to expand studies to document the presence of secondary metabolites and the anti-inflammatory effect of its extracts in animal models. The objective of the present paper was to identify the secondary metabolites present in the ethanol extracts of leaves and fruit of Morinda citrifolia L. collected in the community of San José Rio Manso, municipality of Lalana Choapam, Oaxaca, as well as the evaluation of its anti-inflammatory effect in rabbits. Ethanol extracts were obtained from the green and mature leaves, as well as the juice of the fruit. Green leaf extract gels were prepared and used in a completely randomized experiment in rabbits. The presence of alkaloids, leucoantacionins, amino acids, coumarins, cardiotonics, flavonoids, terpenes and tannins was identified. The 0.5% extract was more efficient at reducing the inflamed area by 55.6% compared to 28.6% of the control, 48 hours after the induction of inflammation. No signs of adverse reactions due to the use of the pharmaceutical forms evaluated were observed.

scholarly journals EFEK ANTIINFLAMASI PERASAN KERING BUAH Morinda citrifolia Linn SECARA PER ORAL PADA TIKUS PUTIH

2003 ◽  
Vol 9 (1) ◽  
pp. 53-55
Author(s):  
Wahjo Dyatmiko ◽  
Suprapto Maat ◽  
Idha Kusumawati ◽  
Gemparing Bayu Wiyoto
Keyword(s):  
Body Weight ◽  
Acetic Acid ◽  
Vascular Permeability ◽  
Test Method ◽  
Morinda Citrifolia ◽  
Inflammatory Activity ◽  
Writhing Test ◽  
Bioactivity Assay ◽  
Anti Inflammatory ◽  
Per Oral

Research on anti inflammatory activity of the fruit of Morinda citrifolia Linn. Or known as pace in Indonesia language has been done by using three methods of assays i.e. anti inflammatory bioactivity assay by measuring the reduction of carrageen-induced oedema in rats analgesic bioactivity assay using writhing test method on mice, and vascular permeability bioactivity assay on mice induced by acetic acid. Results showed that dried juice of the fruit at the dose 1500 mg/kg body weight decreased the volume of oedema up to 64 percent and reduced the pain up to 54 percent. At the dose 2100 mg/kg body weight the dried juice reduced the vascular permeability up to 72 percent.

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