Unprecedented Improvement of Near-Infrared Photothermal Conversion Efficiency to 87.2% by Ultrafast Non-radiative Decay of Excited States of Self-Assembly Cocrystal

2021 ◽  
pp. 5796-5801
Author(s):  
Wenbin Chen ◽  
Shanshan Sun ◽  
Guanheng Huang ◽  
Shaofei Ni ◽  
Liang Xu ◽  
...  
Keyword(s):  
Excited States ◽  
Conversion Efficiency ◽  
Self Assembly ◽  
Radiative Decay ◽  
Near Infrared ◽  
Photothermal Conversion ◽  
Decay Of Excited States

Regulating morphologies and near-infrared photothermal conversion of perylene bisimide via sequence-dependent peptide self-assembly

2018 ◽  
Vol 54 (18) ◽  
pp. 2208-2211 ◽  
Author(s):  
Lingyun Cui ◽  
Yang Jiao ◽  
Anhe Wang ◽  
Luyang Zhao ◽  
Qianqian Dong ◽  
...  
Keyword(s):  
Conversion Efficiency ◽  
Self Assembly ◽  
Near Infrared ◽  
Aqueous Media ◽  
Radical Anions ◽  
Photothermal Conversion ◽  
Perylene Bisimide ◽  
Sequence Dependent

The behavior of PBI self-assembly can be precisely organised by the conjugation of sequence dependent dipeptides in aqueous media resulting in different assembled nanostructures with improved radical anions yield and enhanced photothermal conversion efficiency.

Shape tunable gallium nanorods mediated tumor enhanced ablation through near-infrared photothermal therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 2655-2667 ◽  
Author(s):  
Xuyang Sun ◽  
Mengmeng Sun ◽  
Miaomiao Liu ◽  
Bo Yuan ◽  
Weiping Gao ◽  
...  
Keyword(s):  
Liquid Metal ◽  
Metal Nanoparticles ◽  
Conversion Efficiency ◽  
Photothermal Therapy ◽  
Tumor Targeting ◽  
Near Infrared ◽  
Photothermal Conversion

Shape tunable liquid metal nanoparticles were fabricated with characterization of biocompatibility, favorable photothermal conversion efficiency and tumor targeting capability for photothermal therapy.

Photonic cancer nanomedicine using the near infrared-II biowindow enabled by biocompatible titanium nitride nanoplatforms

2019 ◽  
Vol 4 (2) ◽  
pp. 415-425 ◽  
Author(s):  
Chunmei Wang ◽  
Chen Dai ◽  
Zhongqian Hu ◽  
Hongqiang Li ◽  
Luodan Yu ◽  
...  
Keyword(s):  
Titanium Nitride ◽  
Conversion Efficiency ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Photothermal Conversion ◽  
Theranostic Agent ◽  
Tumor Hyperthermia ◽  
Cancer Nanomedicine

Titanium nitride nanoparticles with high photothermal-conversion efficiency and desirable biocompatibility have been constructed as an alternative theranostic agent for NIR-II laser-excited photoacoustic imaging-guided photothermal tumor hyperthermia.

scholarly journals Self-Assembly Iron Oxide Nanoclusters for Photothermal-Mediated Synergistic Chemo/Chemodynamic Therapy

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Xiang Li ◽  
Zhen Wang ◽  
Mian Ma ◽  
Zhouqing Chen ◽  
Xiang-long Tang ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Self Assembly ◽  
Near Infrared ◽  
Light Irradiation ◽  
Infrared Light ◽  
Photothermal Effect ◽  
Photothermal Conversion ◽  
Assembly Method

Background and Purpose. Although chemodynamic therapy (CDT) is promising for cancer treatment, its clinical application is still limited because of unresolved issues. In this study, an efficient CDT agent for synergistic chemo/CDT therapy mediated by the photothermal effect was developed by an iron oxide self-assembly method. Methods. Superparamagnetic iron oxide nanoclusters (SPIOCs) were located within the core, which resulted in high photothermal conversion and outstanding generation of reactive oxygen species (ROS). The shell consisted of a human serum albumin- (HSA-) paclitaxel (PTX) layer, which extended the blood circulation time and ensured the effectiveness of the chemotherapy. Arg-Gly-Asp peptides (RGD) were linked to the naked cysteine moieties in HSA to promote the specific targeting of human glioma U87 cells by αvβ3 integrins. Continuous near-infrared light irradiation triggered and promoted the synergistic chemo/CDT therapy through the photothermal effect. Results. Our SPIOCs@HSA-RGD nanoplatform showed well biocompatibility and could target glioma specifically. Photothermal conversion and ROS burst were detected after continuous 808 nm light irradiation, and a significant antitumor effect was achieved. Conclusion. Experimental in vitro and in vivo evaluations showed that our photothermal-mediated chemo/CDT therapy could efficiently inhibit tumor growth and is therefore promising for cancer therapy.

scholarly journals Enhancing the Stability and Photothermal Conversion Efficiency of ICG by Pillar[5]arene-Based Host-Guest Interaction

2021 ◽  
Vol 9 ◽  
Author(s):  
Yue Ding ◽  
Chenwei Wang ◽  
Bing Lu ◽  
Yong Yao
Keyword(s):  
Conversion Efficiency ◽  
Near Infrared ◽  
Treatment Time ◽  
Weak Acid ◽  
Water Soluble ◽  
Photothermal Conversion ◽  
New Type ◽  
The Stability ◽  
Neutral Conditions

Indocyanine green (ICG) is a classical near-infrared (NIR) photothermal reagent that can be employed in clinical medical detection. Under neutral conditions, ICG can adsorb NIR light effectively for photothermal (PTT) and photodynamic (PDT) therapy. However, ICG is easily degraded in weak acid environments, which seriously restricts its application. In this work, a cationic water-soluble pillar[5]arene (WP5) was selected as the stabilizing agent for ICG. Thanks to the host-guest interaction between WP5 and alkyl sulfonate, the stability and the photothermal conversion efficiency of ICG increased remarkably upon addition of WP5 as investigated by UV-vis spectrum and photothermal studies. Furthermore, an in vitro study showed higher efficiency of WP5&ICG in killing cancer cells in a shorter treatment time than the free ICG. Hence, it is hopeful that WP5 can be a new type of supramolecular host in enhancing the stability and photothermal conversion efficiency of photosensitizers.

scholarly journals Polydopamine-decorated tobacco mosaic virus for photoacoustic/magnetic resonance bimodal imaging and photothermal cancer therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (19) ◽  
pp. 9760-9768 ◽  
Author(s):  
He Hu ◽  
Qi Yang ◽  
Simona Baroni ◽  
Hong Yang ◽  
Silvio Aime ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Cancer Therapy ◽  
Tobacco Mosaic Virus ◽  
Mosaic Virus ◽  
Conversion Efficiency ◽  
Infrared Absorption ◽  
Near Infrared ◽  
Photothermal Conversion ◽  
Bimodal Imaging ◽  
Good Biocompatibility

The Gd-TMV–PDA nanotheranostic reagents demonstrated highly r1-relaxivity of ∼80 mM−1 s−1 at 60 MHz, strong near-infrared absorption with high photothermal conversion efficiency (28.9%), excellent photoacoustic contrast and good biocompatibility.

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