scholarly journals Macroscopic Supramolecular Assembly Strategy to Construct 3D Biocompatible Microenvironments with Site-Selective Cell Adhesion

Author(s):  
Changyu Wang ◽  
Cuiling Lin ◽  
Rui Ming ◽  
Xiangxin Li ◽  
Pascal Jonkheijm ◽  
...  

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Chao Liu ◽  
Qiang Sun ◽  
Lina Lin ◽  
Jing Wang ◽  
Chaoqi Zhang ◽  
...  

Abstract Assembly of different metal-organic framework (MOF) building blocks into hybrid MOF-on-MOF heterostructures is promising in chemistry and materials science, however the development of ternary MOF-on-MOF heterostructures with controllable architectural and compositional complexity is challenging. Here we report the synthesis of three types of ternary MOF-on-MOF heterostructures via a multiple selective assembly strategy. This strategy relies on the choice of one host MOF with more than one facet that can arrange the growth of a guest MOF, where the arrangement is site-selective without homogenous growth of guest MOF or homogenous coating of guest on host MOF. The growth of guest MOF on a selected site of host MOF in each step provides the opportunity to further vary the combinations of arrangements in multiple steps, leading to ternary MOF-on-MOF heterostructures with tunable complexity. The developed strategy paves the way towards the rational design of intricate and unprecedented MOF-based superstructures for various applications.



Author(s):  
Pengliang Sui ◽  
Qiuhong Li ◽  
Huajie Yu ◽  
Dongqin Luo ◽  
Zhaoyu Zhang ◽  
...  


Author(s):  
Wei-Hang Jin ◽  
Qian Wang ◽  
Meng Chen ◽  
Qi Zhang ◽  
Da-Hui Qu

This research revealed a class of fluorescent materials which have a response to humidity, based on simple small molecules via a CB[8]-based supramolecular assembly strategy, in which the materials’ fluorescent properties can be dynamically controlled.



2020 ◽  
Vol 21 (9) ◽  
pp. 3713-3723
Author(s):  
Hiromichi Sumida ◽  
Yuta Yoshizaki ◽  
Akinori Kuzuya ◽  
Yuichi Ohya


1997 ◽  
Vol 110 (23) ◽  
pp. 2895-2904 ◽  
Author(s):  
C. Brakebusch ◽  
E. Hirsch ◽  
A. Potocnik ◽  
R. Fassler

Integrins are heterodimeric cell adhesion proteins connecting the extracellular matrix to the cytoskeleton and transmitting signals in both directions. These integrins are suggested to be involved in many different biological processes such as growth, differentiation, migration, and cell death. Of more than 20 known integrins, 10 contain the nearly ubiquitously expressed beta1 integrin subunit. Disruption of the beta1 integrin gene by homologous recombination allows us to assess the supposed functions of beta1 containing integrins in vivo in a new way. This review will present and discuss recent findings derived from such studies concerning the biological roles of beta1 integrins in early development, differentiation and migration, hematopoiesis, tumorigenesis, and supramolecular assembly of extracellular matrix proteins. While several former results were confirmed, others were contradicted and new functions found, significantly changing the previous view of beta1 integrin function in vivo.



Author(s):  
U. Aebi ◽  
R. Millonig ◽  
H. Salvo

To date, most 3-D reconstructions of undecorated actin filaments have been obtained from actin filament paracrystal data (for refs, see 1,2). However, due to the fact that (a) the paracrystals may be several filament layers thick, and (b) adjacent filaments may sustantially interdigitate, these reconstructions may be subject to significant artifacts. None of these reconstructions has permitted unambiguous tracing or orientation of the actin subunits within the filament. Furthermore, measured values for the maximal filament diameter both determined by EM and by X-ray diffraction analysis, vary between 6 and 10 nm. Obviously, the apparent diameter of the actin filament revealed in the EM will critically depend on specimen preparation, since it is a rather flexible supramolecular assembly which can easily be bent or distorted. To resolve some of these ambiguities, we have explored specimen preparation conditions which may preserve single filaments sufficiently straight and helically ordered to be suitable for single filament 3-D reconstructions, possibly revealing molecular detail.



2001 ◽  
Vol 120 (5) ◽  
pp. A194-A194
Author(s):  
T SHIGEMATSU ◽  
C ROSS ◽  
J MCCORD ◽  
D GRANGER
Keyword(s):  


2005 ◽  
Vol 173 (4S) ◽  
pp. 170-170
Author(s):  
Maxine G. Tran ◽  
Miguel A. Esteban ◽  
Peter D. Hill ◽  
Ashish Chandra ◽  
Tim S. O'Brien ◽  
...  


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