Porous Iron-Carboxylate Metal–Organic Framework: A Novel Bioplatform with Sustained Antibacterial Efficacy and Nontoxicity

2017 ◽  
Vol 9 (22) ◽  
pp. 19248-19257 ◽  
Author(s):  
Sha Lin ◽  
Xiangmei Liu ◽  
Lei Tan ◽  
Zhenduo Cui ◽  
Xianjin Yang ◽  
...  
Molecules ◽  
2019 ◽  
Vol 24 (7) ◽  
pp. 1211 ◽  
Author(s):  
Gongsen Chen ◽  
Xin Leng ◽  
Juyuan Luo ◽  
Longtai You ◽  
Changhai Qu ◽  
...  

A MIL series metal‒organic framework (MOF), MIL-100(Fe), was successfully synthesized at the nanoscale and fully characterized by TEM, TGA, XRD, FTIR, DLS, and BET. A toxicological assessment was performed using two different cell lines: human normal liver cells (HL-7702) and hepatocellular carcinoma (HepG2). In vitro cytotoxicity of MIL-100(Fe) was evaluated by the MTT assay, LDH releasing rate assay, DAPI staining, and annexin V/PI double staining assay. The safe dose of MIL-100(Fe) was 80 μg/mL. It exhibited good biocompatibility, low cytotoxicity, and high cell survival rate (HL-7702 cells’ viability >85.97%, HepG2 cells’ viability >91.20%). Therefore, MIL-100(Fe) has a potential application as a drug carrier.


2014 ◽  
Vol 20 (40) ◽  
pp. 12864-12873 ◽  
Author(s):  
Daniel Aravena ◽  
Zulema Arcís Castillo ◽  
M. Carmen Muñoz ◽  
Ana B. Gaspar ◽  
Ko Yoneda ◽  
...  

2015 ◽  
Vol 213 ◽  
pp. 14-21 ◽  
Author(s):  
Martina Pilloni ◽  
Franco Padella ◽  
Guido Ennas ◽  
Sarah Lai ◽  
Mariangela Bellusci ◽  
...  

2017 ◽  
Vol 53 (11) ◽  
pp. 1840-1843 ◽  
Author(s):  
Yan Zhang ◽  
Chaoqun Liu ◽  
Faming Wang ◽  
Zhen Liu ◽  
Jinsong Ren ◽  
...  

Iron carboxylate metal–organic frameworks supporting CpG ODNs were fabricated to enhance both the immune response of the CpG ODNs and the ability to image them using T2-magnetic resonance imaging.


2020 ◽  
Vol 1 (7) ◽  
pp. 2509-2519
Author(s):  
Morven J. Duncan ◽  
Paul S. Wheatley ◽  
Emma M. Coghill ◽  
Simon M. Vornholt ◽  
Stewart J. Warrender ◽  
...  

Sufficient concentration of nitric oxide is released from metal organic framework loaded polymer films to impart antibacterial efficacy.


2011 ◽  
Vol 115 (38) ◽  
pp. 18683-18695 ◽  
Author(s):  
Naseem A. Ramsahye ◽  
Thuy Khuong Trung ◽  
Sandrine Bourrelly ◽  
Qingyuan Yang ◽  
Thomas Devic ◽  
...  

2013 ◽  
Vol 1 (34) ◽  
pp. 4231 ◽  
Author(s):  
Valentina Agostoni ◽  
Resmi Anand ◽  
Sandra Monti ◽  
Shaun Hall ◽  
Guillaume Maurin ◽  
...  

2020 ◽  
Vol 55 (28) ◽  
pp. 13785-13798
Author(s):  
Yanita Devi ◽  
Ignatius Ang ◽  
Felycia Edi Soetaredjo ◽  
Shella Permatasari Santoso ◽  
Wenny Irawaty ◽  
...  

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