antibacterial efficacy
Recently Published Documents


TOTAL DOCUMENTS

803
(FIVE YEARS 307)

H-INDEX

43
(FIVE YEARS 10)

2022 ◽  
Vol 52 ◽  
pp. 182-191
Author(s):  
Susanne Meile ◽  
Jiemin Du ◽  
Matthew Dunne ◽  
Samuel Kilcher ◽  
Martin J Loessner

2022 ◽  
Author(s):  
Mina Biria ◽  
Yasaman Rezvani ◽  
Romina Roodgarian ◽  
Abbas Rabbani ◽  
Parastoo Iranparvar

Abstract Background: The inclusion of herbal antibacterial agents in the composition of toothpastes is becoming increasingly popular, due to lower side effects. The present study intended to investigate the antibacterial efficacy of a herbal toothpaste containing Bamboo salt on cariogenic oral bacteria. Methods: The present double-blinded parallel randomized controlled clinical trial was conducted on 60 dental students (age range: 18-30). Following the baseline saliva sampling, the participants were randomly assigned into the case and control groups, to use the Bamboo salt herbal toothpaste and conventional non-herbal toothpaste, respectively. They were instructed to brush their teeth twice a day using the Bass technique. Saliva sampling was repeated after four weeks. The salivary counts of Streptococcus mutans and Lactobacillus at baseline and 4-week follow-up were determined and presented as the logarithm of colony-forming units per milliliter (log CFU/mL). statistical analysis was performed using independent samples t-test and paired sample t-test (P<0.05). Results: A significant decrease in salivary Streptococcus mutans and Lactobacillus was observed using both toothpastes (*P<0.001). The difference between the antibacterial efficacy of two toothpaste types on Streptococcus mutans and Lactobacillus was not statistically significant (P=0.530, and P=0.137, respectively). Conclusion: Due to the comparable efficacy of the investigated herbal toothpaste with conventional toothpaste, it potentially qualifies as a complementary agent for self-care oral hygiene procedures. Trial registration: This trial was registered in the “Iranian Registry of Clinical Trials” (IRCT20210414050964N1) on 21/06/2021.


2022 ◽  
Author(s):  
Nabil A. Ibrahim ◽  
Basma M. Eid ◽  
El-Amir M. Emam

AbstractA green facile nano-finishing route was developed to impart high antibacterial efficacy, UV-protection, self-cleaning and anti-wrinkle functions to cotton/wool and viscose/wool blends using TiO2, and/or Ag-NPs, as active ingredients, along with citric acid and/or succinic acid/ SHP as ester-crosslinking/fixing systems. The data so obtained demonstrated that outstanding durable functional properties can be achieved using the following formulation: TiO2/Ag-NPs (20 g/L each), citric acid/SHP (50 g/L/30 g/L) and the pad- dry microwave fixation at 1300 W for 5 min. SEM and EDX analysis for selected samples as well mode of interactions among the nominated finishing ingredients and the treated substrates were also investigated.


Pharmaceutics ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 130
Author(s):  
Reem E. Alarfaj ◽  
Manal M. Alkhulaifi ◽  
Ahmed J. Al-Fahad ◽  
Shokran Aljihani ◽  
Alaa Eldeen B. Yassin ◽  
...  

The antibacterial activity and biofilm reduction capability of liposome formulations encapsulating tobramycin (TL), and Tobramycin-N-acetylcysteine (TNL) were tested against tobramycin-resistant strains of E. coli, K. pneumoniae and A. baumannii in the presence of several resistant genes. All antibacterial activity were assessed against tobramycin-resistant bacterial clinical isolate strains, which were fully characterized by whole-genome sequencing (WGS). All isolates acquired one or more of AMEs genes, efflux pump genes, OMP genes, and biofilm formation genes. TL formulation inhibited the growth of EC_089 and KP_002 isolates from 64 mg/L and 1024 mg/L to 8 mg/L. TNL formulation reduced the MIC of the same isolates to 16 mg/L. TNL formulation was the only effective formulation against all A. baumannii strains compared with TL and conventional tobramycin (in the plektonic environment). Biofilm reduction was significantly observed when TL and TNL formulations were used against E. coli and K. pneumoniae strains. TNL formulation reduced biofilm formation at a low concentration of 16 mg/L compared with TL and conventional tobramycin. In conclusion, TL and TNL formulations particularly need to be tested on animal models, where they may pave the way to considering drug delivery for the treatment of serious infectious diseases.


2021 ◽  
Vol 22 (3) ◽  
pp. 341-345
Author(s):  
Aparajita Gupta ◽  
Mandeep Kaur

In the present study antibacterial efficacy of  aqueous and methanol extract obtained from leaves and stem of Ocimum sanctum L. was evaluated against certain test bacterial species viz. Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, and Bacillus cereus. It is a traditional medicinal herb, commonly used for the treatment of various human health disorders.  The antibacterial activity was determined by using agar well diffusion method. Among the solvent extracts tested, aqueous extract of leaves exhibited higher antibacterial activity as compared to methanolic extract of leaves. Maximum antibacterial activity was recorded 17.6 mm against Bacillus cereus and minimum value was recorded 14 mm against S. aureus. Maximum antibacterial efficacy of O. sanctum leaves was found 7.3mm against P. aeruginosa and minimum value was 5mm against B. cereus in methanolic extract. Similar trend has been observed in extract of stem of O. sanctum in aqueous and methanolic solvent. The antibacterial efficacy has been found nil in methanolic extract. However in aqueous extract moderate activity has been recorded i.e. 9.3 mm against E.coli and minimum 7.3 mm against K. pneumoniae. The trend of phytochemicals revealed non significant variation. Phytochemical analysis of leaves and stem extracts of O. sanctum revealed the presence of various phytoconstituents i.e. alkaloids, flavonoids, saponins, tanins, glycosides.


Author(s):  
Aniruddha Das ◽  
Puja C Yavagal

Syzygium cumini leaf extract possess a range of pharmacological properties such as anti-diabetic, anti-inflammatory, antiulcerogenic, cardioprotective, antidiarrheal, antimicrobial, antioxidant and hepatoprotective activities. Objective of the study was to evaluate and compare the antibacterial efficacy of 0.4% Syzygium cumini leaf extract and 0.2% chlorhexidine containing mouthwashes on salivary Streptococcus mutans among children aged 7-8 years in a hospital setting. Methods: Twenty-four school children aged 7-8 years, fulfilling the eligibility criteria, were randomized into two groups. Group 1: received 0.4% S. cumini leaf extract mouth wash and Group 2: received 0.2% chlorhexidine mouth wash. Saliva samples of the children were collected before and one hour after mouth rinsing with 10 ml of interventional mouthwash, for S. mutans count analysis. Results: The results of the study showed that there was significant reduction in salivary S. mutans counts in both the groups post mouth rinsing with interventional solutions (p=0.002). However, intergroup comparison reveled that in Chlorhexidine group there was significantly more reduction in Salivary S mutans counts compared to Syzygium cumini mouth rinsing group. (p=0.03) Conclusion: There was reduction in salivary S mutans counts after mouth rinsing with Syzygium cumini leaf extract. Hence, Syzygium cumini leaf extract mouthwash could be an effective aid for prevention and control of dental caries since it is safe, culturally acceptable and feasible.


Sign in / Sign up

Export Citation Format

Share Document