scholarly journals Correction to “Complementary Genomic Bioinformatics and Chemical Approaches Facilitate the Absolute Structure Assignment of Ionostatin, a Linear Polyketide from a Rare Marine-Derived Actinomycete”

2021 ◽  
Author(s):  
Min Cheol Kim ◽  
Jaclyn M. Winter ◽  
Henrique Machado ◽  
Reiko Cullum ◽  
Zhifei Li ◽  
...  
Keyword(s):  
The Absolute ◽  
Structure Assignment ◽  
Absolute Structure

Using thet-distribution to improve the absolute structure assignment with likelihood calculations

2010 ◽  
Vol 43 (4) ◽  
pp. 665-668 ◽  
Author(s):  
Rob W. W. Hooft ◽  
Leo H. Straver ◽  
Anthony L. Spek
Keyword(s):  
Structure Determination ◽  
Systematic Errors ◽  
Error Distribution ◽  
Good Data ◽  
The Absolute ◽  
Non Gaussian ◽  
Structure Assignment ◽  
Absolute Structure

The previously described method for absolute structure determination [Hooft, Straver & Spek (2008).J. Appl. Cryst.41, 96–103] assumes a Gaussian error distribution. The method is now extended to make it robust against poor data with large systematic errors with the introduction of the Studentt-distribution. It is shown that this modification makes very little difference for good data but dramatically improves results for data with a non-Gaussian error distribution.

Total synthesis and absolute structure of N55, a positive modulator of GLP-1 signaling

2020 ◽  
Vol 18 (43) ◽  
pp. 8899-8907
Author(s):  
Nai-Pin Lin ◽  
Rong-Jie Chein
Keyword(s):  
Total Synthesis ◽  
Positive Modulator ◽  
Glucagon Like Peptide ◽  
The Absolute ◽  
Glucagon Like Peptide 1 ◽  
Absolute Structure

The absolute structure of N55, a positive modulator of Glucagon-like peptide-1 (GLP-1) signaling, was determined by a 7-step total synthesis with 29% overall yield.

scholarly journals Absolute structure determination of compounds with axial and planar chirality using the crystalline sponge method

2015 ◽  
Vol 6 (7) ◽  
pp. 3765-3768 ◽  
Author(s):  
Shota Yoshioka ◽  
Yasuhide Inokuma ◽  
Manabu Hoshino ◽  
Takashi Sato ◽  
Makoto Fujita
Keyword(s):  
Structure Determination ◽  
Asymmetric Syntheses ◽  
Planar Chirality ◽  
The Absolute ◽  
Absolute Structure

The absolute structure determination of compounds with axial and planar chirality obtained by recently developed asymmetric syntheses was achieved using the crystalline sponge method without using any reference compounds or synthetic modifications.

scholarly journals The absolute structure and synthesis of wenjine isolated from Curcuma wenyujin.

1991 ◽  
Vol 39 (4) ◽  
pp. 854-856 ◽  
Author(s):  
Ji-Fu GAO ◽  
Ji-Hong XIE ◽  
Kenzo HARIMAYA ◽  
Takeshi KAWAMATA ◽  
Yoichi IITAKA ◽  
...  
Keyword(s):  
The Absolute ◽  
Absolute Structure

Chiral Crystalline Sponges for the Absolute Structure Determination of Chiral Guests

2017 ◽  
Vol 139 (33) ◽  
pp. 11341-11344 ◽  
Author(s):  
KaKing Yan ◽  
Ritesh Dubey ◽  
Tatsuhiko Arai ◽  
Yasuhide Inokuma ◽  
Makoto Fujita
Keyword(s):  
Structure Determination ◽  
The Absolute ◽  
Absolute Structure

Absolute chirality of the γ-polymorph of glycine: correlation of the absolute structure with the optical rotation

2012 ◽  
Vol 48 (48) ◽  
pp. 6031 ◽  
Author(s):  
Kazuhiko Ishikawa ◽  
Masahito Tanaka ◽  
Toshiya Suzuki ◽  
Akiko Sekine ◽  
Tsuneomi Kawasaki ◽  
...  
Keyword(s):  
Optical Rotation ◽  
The Absolute ◽  
Absolute Chirality ◽  
Absolute Structure

Enzymatic Synthesis of Four Stereoisomers of 7-0xo-biopterin and Determination of the Absolute Structure of Ichthyopterin

Pteridines ◽  
1990 ◽  
Vol 2 (3) ◽  
pp. 151-156 ◽  
Author(s):  
Shin Ichiro Takikawa ◽  
Sadao Matsuura
Keyword(s):  
Enzymatic Synthesis ◽  
Side Chain ◽  
Side Chains ◽  
Enzymatic Conversion ◽  
Cd Spectra ◽  
The Absolute ◽  
Chiral Centers ◽  
Absolute Structure

Summary Enzymatic conversion of stereoisomers of biopterin (3a-d) to the 7-oxo-biopterin isomers (4a-d) was performed with a new pterin 7-oxidase extracted from carp skin. The chiral centers of the 6-side chains of biopterin isomers were preserved during the conversion, and the four possible stereoisomers of 7-oxo-biopterin (4a-d) were obtained from the corresponding biopterin isomers (3a-d). HPLC and CD spectra studies showed that natural ichthyopterin is 2-amino-6-(L-erythro-1',2' -dihydroxypropyl)-4, 7(3H,8H)-pteridinedione (4a) which has the same L-erythro structure at the side chain as natural biopterin (3a). This fact suggests that ichthyopterin is biologically derived from biopterin in these fishes.

scholarly journals Structure of Equilenin at 100 K: an estrone-related steroid

2017 ◽  
Vol 73 (8) ◽  
pp. 1223-1226
Author(s):  
Christopher S. Frampton ◽  
David D. MacNicol
Keyword(s):  
Hydrogen Bonds ◽  
Resonant Scattering ◽  
Methyl Group ◽  
Axis Direction ◽  
Envelope Conformation ◽  
The Absolute ◽  
Absolute Structure

The structure of the estrone-related steroid, Equilenin, C18H18O2 (systematic name 3-hydroxy-13-methyl-11,12,13,14,15,16-hexahydrocyclopenta[a]phenanthren-17-one), has been determined at 100 K. The crystals are orthorhombic, P212121, and the absolute structure of the molecule in the crystal has been determined by resonant scattering [Flack parameter = −0.05 (4)]. The C atoms of the A and B rings are almost coplanar, with an r.m.s. deviation from planarity of 0.0104 Å. The C ring has a sofa conformation, while the D ring has an envelope conformation with the methine C atom as the flap. The keto O atom and the methyl group are translated 0.78 and 0.79 Å, respectively, from the equivalent positions on 17β-estrone. In the crystal, molecules are linked by O—H...O hydrogen bonds, forming chains parallel to the c-axis direction.

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