Total synthesis and absolute structure of N55, a positive modulator of GLP-1 signaling

2020 ◽  
Vol 18 (43) ◽  
pp. 8899-8907
Author(s):  
Nai-Pin Lin ◽  
Rong-Jie Chein
Keyword(s):  
Total Synthesis ◽  
Positive Modulator ◽  
Glucagon Like Peptide ◽  
The Absolute ◽  
Glucagon Like Peptide 1 ◽  
Absolute Structure

The absolute structure of N55, a positive modulator of Glucagon-like peptide-1 (GLP-1) signaling, was determined by a 7-step total synthesis with 29% overall yield.

The First Total Synthesis of Cochleamycin A and Determination of the Absolute Structure.

ChemInform ◽  
2003 ◽  
Vol 34 (48) ◽  
Author(s):  
Kuniaki Tatsuta ◽  
Fumie Narazaki ◽  
Nobusuke Kashiki ◽  
Jun-Ichiro Yamamoto ◽  
Satoshi Nakano
Keyword(s):  
Total Synthesis ◽  
The Absolute ◽  
Absolute Structure

scholarly journals The First Total Synthesis of Cochleamycin A and Determination of the Absolute Structure

2003 ◽  
Vol 56 (6) ◽  
pp. 584-590 ◽  
Author(s):  
KUNIAKI TATSUTA ◽  
FUMIE NARAZAKI ◽  
NOBUSUKE KASHIKI ◽  
JUN-ICHIRO YAMAMOTO ◽  
SATOSHI NAKANO
Keyword(s):  
Total Synthesis ◽  
The Absolute ◽  
Absolute Structure

scholarly journals Isolation of Positive Modulator of Glucagon-like Peptide-1 Signaling fromTrigonella foenum-graecum(Fenugreek) Seed

2015 ◽  
Vol 290 (43) ◽  
pp. 26235-26248 ◽  
Author(s):  
Klim King ◽  
Nai-Pin Lin ◽  
Yu-Hong Cheng ◽  
Gao-Hui Chen ◽  
Rong-Jie Chein
Keyword(s):  
Fenugreek Seed ◽  
Positive Modulator ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

Effects of glucagon-like peptide-1 (GLP-1) on gastric accommodation, emptying and satiety in humans

2001 ◽  
Vol 120 (5) ◽  
pp. A74-A74
Author(s):  
S AROS ◽  
D KIM ◽  
D BURTON ◽  
G THOMFORDE ◽  
A VELLA ◽  
...  
Keyword(s):  
Gastric Accommodation ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

Eine häufige genetische Variation in WFS1 bedingt eine gestörte Glucagon-like Peptide-1-induzierte Insulinsekretion

2009 ◽  
Vol 4 (S 01) ◽  
Author(s):  
K Müssig ◽  
SA Schäfer ◽  
H Staiger ◽  
F Machicao ◽  
N Stefan ◽  
...  
Keyword(s):  
Genetische Variation ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

Dulaglutide, a glucagon-like peptide-1 receptor agonist: in the search for survival molecule

2020 ◽  
Vol 9 (2) ◽  
pp. 49-58
Author(s):  
A.S. Ametov ◽  
◽  
A.O. Nevolnikova ◽  
E.A. Tertychnaya ◽  
O.A. Mishra ◽  
...  
Keyword(s):  
Receptor Agonist ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

Liraglutide, a glucagon-like peptide-1 receptor agonist, improves bone mass and architecture in ovariectomised mice

2014 ◽  
Author(s):  
Marie Pereira ◽  
Jeshmi Jeyabalan ◽  
Camilla Sofie Jorgensen ◽  
Mark Cleasby ◽  
Mark Hopkinson ◽  
...  
Keyword(s):  
Bone Mass ◽  
Receptor Agonist ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1
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